ChemicalBook > CAS DataBase List > Ethyl 2-amino-4-methylthiazole-5-carboxylate

Ethyl 2-amino-4-methylthiazole-5-carboxylate

Product Name
Ethyl 2-amino-4-methylthiazole-5-carboxylate
CAS No.
7210-76-6
Chemical Name
Ethyl 2-amino-4-methylthiazole-5-carboxylate
Synonyms
AKOS BB-9152;AKOS B000345;ASISCHEM Y51232;BUTTPARK 34\01-17;IFLAB-BB F1920-0015;TIMTEC-BB SBB000257;OTAVA-BB BB0108540072;2-Amino-4-methyl-5-carbethoxythiazole;ETHYL 2-AMINO-4-METHYLTHIAZOLE-5-CARBOX&;2-Amino-4-methyl-5-ethoxycarbonyl-thiazole
CBNumber
CB5118669
Molecular Formula
C7H10N2O2S
Formula Weight
186.23
MOL File
7210-76-6.mol
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Ethyl 2-amino-4-methylthiazole-5-carboxylate Property

Melting point:
176-180 °C(lit.)
Boiling point:
313.1±22.0 °C(Predicted)
Density 
1.283±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml; Ethanol:PBS pH 7.2 (1:1): 0.5 mg/ml
form 
powder to crystal
pka
3.90±0.10(Predicted)
color 
White to Almost white
Water Solubility 
insoluble
InChI
InChI=1S/C7H10N2O2S/c1-3-11-6(10)5-4(2)9-7(8)12-5/h3H2,1-2H3,(H2,8,9)
InChIKey
WZHUPCREDVWLKC-UHFFFAOYSA-N
SMILES
S1C(C(OCC)=O)=C(C)N=C1N
CAS DataBase Reference
7210-76-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-36-36/37/39-22
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
E0898
Product name
Ethyl 2-Amino-4-methylthiazole-5-carboxylate
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$26
Updated
2025/07/31
TCI Chemical
Product number
E0898
Product name
Ethyl 2-Amino-4-methylthiazole-5-carboxylate
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$88
Updated
2025/07/31
Cayman Chemical
Product number
13059
Product name
Ethyl 2-Amino-4-methylthiazole-5-carboxylate
Purity
≥98%
Packaging
1g
Price
$40
Updated
2024/03/01
Cayman Chemical
Product number
13059
Product name
Ethyl 2-Amino-4-methylthiazole-5-carboxylate
Purity
≥98%
Packaging
5g
Price
$177
Updated
2024/03/01
Cayman Chemical
Product number
13059
Product name
Ethyl 2-Amino-4-methylthiazole-5-carboxylate
Purity
≥98%
Packaging
250mg
Price
$14
Updated
2024/03/01
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Ethyl 2-amino-4-methylthiazole-5-carboxylate Chemical Properties,Usage,Production

Chemical Properties

off-white powder

Uses

Ethyl 2-amino-4-methylthiazole-5-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Synthesis

17356-08-0

609-15-4

7210-76-6

Thiourea (2.55 g, 0.033 mol, 1.1 eq.) was added to a solution of ethyl 2-chloro-3-oxobutanoate (5 g, 0.030 mol, 1 eq.) in ethanol (25 mL) at 25 °C. The reaction mixture was heated to reflux and kept for 3 hours. Upon completion of the reaction, the reaction mixture was slowly cooled to 25 °C under continuous stirring to induce precipitation of the product as a white solid. The precipitated solid was collected by filtration through a Büchner funnel and dried under vacuum to afford ethyl 2-amino-4-methylthiazole-5-carboxylate (4.8 g, 64% yield) as a final fine white powder.

References

[1] Patent: CN108570017, 2018, A. Location in patent: Paragraph 0030; 0031; 0033; 0035; 0037
[2] Chemical Biology and Drug Design, 2016, vol. 87, # 4, p. 508 - 516
[3] Patent: CN102942565, 2016, B. Location in patent: Paragraph 0028-0031; 0087-0088
[4] Archiv der Pharmazie, 2017, vol. 350, # 2,
[5] Acta Poloniae Pharmaceutica - Drug Research, 2017, vol. 74, # 6, p. 1699 - 1709

Ethyl 2-amino-4-methylthiazole-5-carboxylate Preparation Products And Raw materials

Raw materials

Ethanol Ethyl 2-chloroacetoacetate Thiourea

Preparation Products

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Ethyl 2-amino-4-methylthiazole-5-carboxylate Suppliers

Americas 1 Belgium 3 Canada 1 China 159 Europe 1 France 2 Germany 6 India 23 Japan 2 Russia 1 Switzerland 2 Ukraine 1 United Kingdom 21 United States 52 Global 275
Interchim SA
Tel
--
Fax
--
Email
him@interchim.com
Country
France
ProdList
2725
Advantage
58
Interchim S.A.
Tel
--
Fax
--
Email
interchim@interchim.com
Country
France
ProdList
6302
Advantage
76
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View Lastest Price from Ethyl 2-amino-4-methylthiazole-5-carboxylate manufacturers

Career Henan Chemical Co
Product
Ethyl 2-amino-4-methylthiazole-5-carboxylate 7210-76-6
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
150KG
Release date
2019-07-09

7210-76-6, Ethyl 2-amino-4-methylthiazole-5-carboxylateRelated Search:

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  • OTAVA-BB BB0108540072
  • TIMTEC-BB SBB000257
  • JR-6608, Ethyl 2-amino-4-methylthiazole-5-carboxylate, 97%
  • BUTTPARK 34\01-17
  • ASISCHEM Y51232
  • IFLAB-BB F1920-0015
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  • ETHYL 2-AMINO-4-METHYLTHIAZOLE-5-CARBOXYLATE
  • AKOS B000345
  • AKOS BB-9152
  • 2-AMINO-4-METHYL-5-THIAZOLECARBOXYLIC ACID ETHYL ESTER
  • 2-AMINO-4-METHYL-THIAZOLE-5-CARBOXYLIC ACID ETHYL ESTER
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  • ETHYL 2-AMINO-4-METHYLTHIAZOLE-5-CARBOX&
  • Ethyl 2-amino-4-methylthiazole-5-carboxylate 98%
  • 2-Amino-4-methyl-5-ethoxycarbonyl-thiazole
  • Ethyl 2-amino-4-methylthiazole-5-carboxylate,98%
  • 2-Amino-5-(ethoxycarbonyl)-4-methyl-1,3-thiazole
  • Ethyl 2-amino-4-methyl-1,3-thiazole-5-carboxylate 98%
  • Ethyl 2-AMino-4-Methylthiazole-5-carboxylate 7210-76-6
  • 2-Amino-4-methyl-5-carbethoxythiazole
  • 5-Thiazolecarboxylic acid, 2-amino-4-methyl-, ethyl ester
  • ethyl 2-amino-4-methyl-1,3-thiazole-5-carboxylate(SALTDATA: FREE)
  • Ethyl2-Amino-4-methylthiazole-5-carboxylate&gt
  • 5-Thiazolecarboxylic acid, 2-amino-4-methyl-, ethyl ester (7CI, 8CI, 9CI, ACI)
  • 2-amino-4-methyl-5-Thiazolecarboxylic acid ethyl ester (7CI 8CI 9CI ACI)
  • Ethyl 2-amino-4-methylthiazol-5-carboxylate
  • 7210-76-6
  • Building Blocks
  • Heterocyclic Building Blocks
  • Thiazoles
  • API intermediates
  • Building Blocks
  • Heterocyclic Building Blocks
  • Amines
  • blocks
  • Carboxes
  • Thiazoles