Oxetan-3-ol
- Product Name
- Oxetan-3-ol
- CAS No.
- 7748-36-9
- Chemical Name
- Oxetan-3-ol
- Synonyms
- 3-HYDROXYOXETANE;3-Oxetanol;Ooetan-3-ol;Oxetan-3-ol;3-Oxetanol>3-Oxocyclobutanol;Oxetan-3-ol, >=97%;1,3-Epoxy-2-propanol;3-Hydroxyoxetane 95%;3-Oxetanol - [O5686]
- CBNumber
- CB51235204
- Molecular Formula
- C3H6O2
- Formula Weight
- 74.08
- MOL File
- 7748-36-9.mol
Oxetan-3-ol Property
- Boiling point:
- 153℃
- Density
- 1.167
- refractive index
- 1.438
- Flash point:
- 87°(189°F)
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- Chloroform (Soluble), Methanol (Slightly)
- pka
- 13.68±0.20(Predicted)
- form
- Liquid
- color
- Clear colorless
- InChI
- InChI=1S/C3H6O2/c4-3-1-5-2-3/h3-4H,1-2H2
- InChIKey
- QMLWSAXEQSBAAQ-UHFFFAOYSA-N
- SMILES
- O1CC(O)C1
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-37/38-41
- Safety Statements
- 26-39
- RIDADR
- NA 1993 / PGIII
- WGK Germany
- 3
- TSCA
- No
- HS Code
- 29329990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 733296
- Product name
- 3-Hydroxyoxetane
- Purity
- 95%
- Packaging
- 1g
- Price
- $28.1
- Updated
- 2025/07/31
- Product number
- O0409
- Product name
- 3-Oxetanol
- Purity
- >96.0%(GC)
- Packaging
- 1g
- Price
- $27
- Updated
- 2025/07/31
- Product number
- O0409
- Product name
- 3-Oxetanol
- Purity
- >96.0%(GC)
- Packaging
- 5g
- Price
- $78
- Updated
- 2025/07/31
- Product number
- O846575
- Product name
- 3-Oxetanol
- Packaging
- 1g
- Price
- $55
- Updated
- 2021/12/16
- Product number
- O846575
- Product name
- 3-Oxetanol
- Packaging
- 25g
- Price
- $275
- Updated
- 2021/12/16
Oxetan-3-ol Chemical Properties,Usage,Production
Chemical Properties
Colorless Transparent Liquid
Uses
3-Oxetanol is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.
Synthesis
95257-22-0
7748-36-9
General procedure for the synthesis of oxetan-3-ol from 3-(phenylmethoxy)oxetane: 3-(phenylmethoxy)oxetane (59 g, 0.41 mol) and 10% palladium/carbon catalyst were added to methanol (1000 mL) in an autoclave. The hydrogenation reaction was completed by reacting under hydrogen atmosphere (10 atm) at 40°C for 24 hours. Upon completion of the reaction, the palladium/carbon catalyst was removed by filtration, followed by concentration under reduced pressure to remove the solvent. The colorless liquid product oxetan-3-ol (142.63 g) was obtained by distillation in 95.84% yield.
References
[1] Patent: CN103554064, 2016, B. Location in patent: Paragraph 0031; 0032; 0041; 0042
Oxetan-3-ol Preparation Products And Raw materials
Raw materials
Preparation Products
Oxetan-3-ol Suppliers
- Tel
- 800-4238616
- Fax
- +1-888-520-1075 / +1-503-283-1987
- sales@tciamerica.com
- Country
- Americas
- ProdList
- 23653
- Advantage
- 75
View Lastest Price from Oxetan-3-ol manufacturers
- Product
- Oxetan-3-ol 7748-36-9
- Price
- US $30.00-10.00/KG
- Min. Order
- 50KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-24
- Product
- Oxetan-3-ol 7748-36-9
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20 tons
- Release date
- 2023-11-28
- Product
- Oxetan-3-ol 7748-36-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 2000tons
- Release date
- 2019-12-31