ChemicalBook > CAS DataBase List > Oxetan-3-ol

Oxetan-3-ol

Product Name
Oxetan-3-ol
CAS No.
7748-36-9
Chemical Name
Oxetan-3-ol
Synonyms
3-HYDROXYOXETANE;3-Oxetanol;Ooetan-3-ol;Oxetan-3-ol;3-Oxetanol>3-Oxocyclobutanol;Oxetan-3-ol, >=97%;1,3-Epoxy-2-propanol;3-Hydroxyoxetane 95%;3-Oxetanol - [O5686]
CBNumber
CB51235204
Molecular Formula
C3H6O2
Formula Weight
74.08
MOL File
7748-36-9.mol
More
Less

Oxetan-3-ol Property

Boiling point:
153℃
Density 
1.167
refractive index 
1.438
Flash point:
87°(189°F)
storage temp. 
Inert atmosphere,2-8°C
solubility 
Chloroform (Soluble), Methanol (Slightly)
pka
13.68±0.20(Predicted)
form 
Liquid
color 
Clear colorless
InChI
InChI=1S/C3H6O2/c4-3-1-5-2-3/h3-4H,1-2H2
InChIKey
QMLWSAXEQSBAAQ-UHFFFAOYSA-N
SMILES
O1CC(O)C1
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22-37/38-41
Safety Statements 
26-39
RIDADR 
NA 1993 / PGIII
WGK Germany 
3
TSCA 
No
HS Code 
29329990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
733296
Product name
3-Hydroxyoxetane
Purity
95%
Packaging
1g
Price
$28.1
Updated
2025/07/31
TCI Chemical
Product number
O0409
Product name
3-Oxetanol
Purity
>96.0%(GC)
Packaging
1g
Price
$27
Updated
2025/07/31
TCI Chemical
Product number
O0409
Product name
3-Oxetanol
Purity
>96.0%(GC)
Packaging
5g
Price
$78
Updated
2025/07/31
TRC
Product number
O846575
Product name
3-Oxetanol
Packaging
25g
Price
$275
Updated
2021/12/16
TRC
Product number
O846575
Product name
3-Oxetanol
Packaging
1g
Price
$55
Updated
2021/12/16
More
Less

Oxetan-3-ol Chemical Properties,Usage,Production

Chemical Properties

Colorless Transparent Liquid

Uses

3-Oxetanol is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.

Synthesis

95257-22-0

7748-36-9

General procedure for the synthesis of oxetan-3-ol from 3-(phenylmethoxy)oxetane: 3-(phenylmethoxy)oxetane (59 g, 0.41 mol) and 10% palladium/carbon catalyst were added to methanol (1000 mL) in an autoclave. The hydrogenation reaction was completed by reacting under hydrogen atmosphere (10 atm) at 40°C for 24 hours. Upon completion of the reaction, the palladium/carbon catalyst was removed by filtration, followed by concentration under reduced pressure to remove the solvent. The colorless liquid product oxetan-3-ol (142.63 g) was obtained by distillation in 95.84% yield.

References

[1] Patent: CN103554064, 2016, B. Location in patent: Paragraph 0031; 0032; 0041; 0042

Oxetan-3-ol Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Oxetan-3-ol Suppliers

Americas 1 Belgium 1 China 288 Europe 1 Germany 3 India 11 Japan 1 The Netherlands 1 United Kingdom 3 United States 26 Global 336
Zhenjiang D&A Biological Technology Co., Ltd.
Tel
18912101619
Email
wxf2005a@126.com
Country
China
ProdList
94
Advantage
58
NanJing FineTech Chemical Co., Ltd
Tel
025-52078417 17701591256
Email
sales@fine-chemtech.com
Country
China
ProdList
288
Advantage
58
Jinan Shuhong Biotechnology Co., Ltd.
Tel
15665870163 15665870163
Email
6348314@qq.com
Country
China
ProdList
11
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
ChemFuture PharmaTech (Jiangsu) Ltd
Tel
5108538618
Fax
86 510 85386988-8017
Email
suger.wang@chemfuture.com
Country
China
ProdList
832
Advantage
65
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6003
Advantage
61
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
shanghai science Bio-Pharmceutical.co,ltd.
Tel
021-021-57872719 13761402923
Fax
02157872719
Email
245662540@qq.com
Country
China
ProdList
310
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
Advantage
59
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9883
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
16077
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527621225
Email
1791901229@qq.com
Country
China
ProdList
6945
Advantage
52
Shanghai Ennopharm Co., Ltd.
Tel
+86 (21) 6435-5022
Country
China
ProdList
4267
Advantage
65
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
SpringPharma Tech Co.,Ltd
Tel
+86-25-68710855, +86-25-68710897
Fax
025-68710856
Email
sales@springpharma.net
Country
China
ProdList
1261
Advantage
62
Shanghai Chem-Milestone Co., Ltd
Tel
021-50273253 13641951838
Fax
+86-21-61294436
Email
chemmilestone@163.com
Country
China
ProdList
151
Advantage
62
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8669
Advantage
57
Nanjing Vital Chemical Co., Ltd.
Tel
Please Send Email 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
4378
Advantage
65
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
Sphinx Scientific Laboratory (Tianjin) Co., Ltd.
Tel
022-66211289-843 13672102692
Fax
QQ：2377893365
Email
contact@sphinxpharm.com
Country
China
ProdList
361
Advantage
62
Heterochem
Tel
027-88041443 13072715837
Fax
027-51829379
Email
sales@hetero-chem.com
Country
China
ProdList
696
Advantage
58
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Suzhou Sibian Chemical Technology Co.,Ltd.
Tel
0512-65617459 18915409046
Fax
0512-65617459
Email
sales@sibian-chem.com
Country
China
ProdList
1922
Advantage
55
Shanghai Junye chemical Co., Ltd
Tel
021-021-50318666 18516602538
Fax
+86-21-61924293
Email
shlip@163.com
Country
China
ProdList
58
Advantage
58
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
Nanjing Norris-Pharm Technology Co., Ltd
Tel
18652989687
Fax
+86-25-52131256
Email
sales@norris-pharm.com
Country
China
ProdList
8878
Advantage
55
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
150-2103-5486 18017383231
Fax
qq：2817624287
Email
983544897@qq.com
Country
China
ProdList
9342
Advantage
55
Nantong Ayeschem Co., Ltd
Tel
+86-513-86760116
Fax
+86-513-86760116;
Email
sales@ayeschem.com
Country
China
ProdList
99
Advantage
58
Candia Thamtech Company Limited
Tel
0371-86615086 18203638366 0371-86159066 13526786601
Fax
0371-86159066
Country
China
ProdList
2015
Advantage
60
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9546
Advantage
55
Changzhou Chemscaler Pharmtech Co., Ltd.
Tel
0519-81096292 15312577869
Email
chemscaler@yahoo.com.cn
Country
China
ProdList
311
Advantage
60
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
+86-28-85122536 85324413
Fax
+86-28-85326443
Email
market@astatech.cn
Country
China
ProdList
8026
Advantage
55
Chem-Stone Co.,Ltd.
Tel
020-82185713,82185709 13418171485
Fax
020-82185696
Email
sales@chem-stone.com
Country
China
ProdList
744
Advantage
56
Quzhou Juhua Friendship Co., Ltd
Tel
0570-3066667
Fax
0570-3063388
Country
China
ProdList
3930
Advantage
58
Valiant Co., Ltd.
Tel
0535-6101880
Fax
0535-6386989
Email
liutao@valiant-cn.com
Country
China
ProdList
292
Advantage
60
Amatek Scientific Co. Ltd.
Tel
0512-56316828 4008675858
Fax
+86-512-56316826
Email
sales@amateksci.com
Country
China
ProdList
9874
Advantage
55
More
Less

View Lastest Price from Oxetan-3-ol manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
Oxetan-3-ol 7748-36-9
Price
US $30.00-10.00/KG
Min. Order
50KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-24
Hebei Yanxi Chemical Co., Ltd.
Product
Oxetan-3-ol 7748-36-9
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-11-28
Shaanxi Dideu Medichem Co. Ltd
Product
Oxetan-3-ol 7748-36-9
Price
US $0.00-0.00/KG
Min. Order
1g
Purity
99%
Supply Ability
2000tons
Release date
2019-12-31

7748-36-9, Oxetan-3-olRelated Search:

3-Methyl butynol Ketorolac tromethamine Fosfomycin tromethamine 3-Oxetanemethanol oxetane-3-carbaldehyde methyl oxetane-3-carboxylate ethyl 2-(oxetan-3-ylidene)acetate 4,4,5,5-TetraMethyl-2-(oxetan-3-yl)-1,3,2-dioxaborolane oxetan-3-ylmethanol Hydrogenated Cottonseed Oil oxetan-3-yl-acetic acid ethyl ester Ethyl oxetane-3-carboxylate 3-Oxetanethiol 3-OXETANECARBOXYLIC ACID 2-aminomethyloxetane TOLUENE-4-SULFONIC ACID OXETAN-2-YLMETHYL ESTER Oxetan-3-ylmethyl 4-methylbenzenesulfonate Benzyl oxetan-3-ylcarbamate

  • 3-Oxetanol
  • Ooetan-3-ol
  • Oxetan-3-ol, 1,3-Epoxypropan-2-ol
  • 3-Hydroxyoxetane 95%
  • 3 - hydroxyl oxygen heterocyclic butane
  • 1,3-Epoxy-2-propanol
  • Oxetan-3-ol, >=97%
  • Oxetan-3-ol
  • 3-HYDROXYOXETANE
  • 3-Oxetanol&gt
  • 3-Oxetanol (9CI, ACI)
  • 3-Oxocyclobutanol
  • 3-Oxetanol - [O5686]
  • 7748-36-9
  • 748-36-9
  • API intermediates
  • Alcohols and Derivatives
  • Heterocycles
  • Building Blocks/Intermediates
  • Pyridines
  • 1