ChemicalBook > CAS DataBase List > (R)-(-)-N-BENZYL-1-(1-NAPHTHYL)ETHYLAMINE HYDROCHLORIDE

(R)-(-)-N-BENZYL-1-(1-NAPHTHYL)ETHYLAMINE HYDROCHLORIDE

Product Name
(R)-(-)-N-BENZYL-1-(1-NAPHTHYL)ETHYLAMINE HYDROCHLORIDE
CAS No.
163831-65-0
Chemical Name
(R)-(-)-N-BENZYL-1-(1-NAPHTHYL)ETHYLAMINE HYDROCHLORIDE
Synonyms
CicalcetImpurityBHCl;Cinacalcet Impurity B HCl;Cinacalcet Impurity B (HCl salt form);(R)-(-)-N-BENZYL-1-(1-NAPHTHYL)ETHYLAMI&;N-benzyl-1-(1-naphthyl)ethylamine hydrochloride;(R)-N-BENZYL 1-(1-NAPHTHYL)ETHYLAMINE HYDROCHLORIDE;benzyl-(1-naphthalen-1-yl-ethyl)-amine hydrochloride;(R)-N-[1-(1-NAPHTHYL)ETHYL]BENZYLAMINE HYDROCHLORIDE;(R)-(-)-N-BENZYL-1-(1-NAPHTHYL)ETHYLAMINE HYDROCHLORIDE;(R)-N-Benzyl-1-(naphthalen-1-yl)ethanamine hydrochloride
CBNumber
CB5125005
Molecular Formula
C19H20ClN
Formula Weight
297.82
MOL File
163831-65-0.mol
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(R)-(-)-N-BENZYL-1-(1-NAPHTHYL)ETHYLAMINE HYDROCHLORIDE Property

Melting point:
259-261 °C(lit.)
storage temp. 
Inert atmosphere,Room Temperature
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific
Product number
3146CW
Product name
(R)-(-)-N-Benzyl-1-(1-naphthyl)ethylaminehydrochloride
Packaging
250mg
Price
$149
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CCH0007177
Product name
(R)-(-)-N-BENZYL-1-(1-NAPHTHYL)ETHYLAMINE HYDROCHLORIDE
Purity
95.00%
Packaging
5MG
Price
$500.12
Updated
2021/12/16
AK Scientific
Product number
3146CW
Product name
(R)-(-)-N-Benzyl-1-(1-naphthyl)ethylaminehydrochloride
Packaging
1g
Price
$281
Updated
2021/12/16
Crysdot
Product number
CD12135812
Product name
(R)-N-Benzyl-1-(naphthalen-1-yl)ethanaminehydrochloride
Purity
95+%
Packaging
250mg
Price
$388
Updated
2021/12/16
Alichem
Product number
163831650
Product name
(R)-N-Benzyl-1-(naphthalen-1-yl)ethanaminehydrochloride
Packaging
250mg
Price
$435.12
Updated
2021/12/16
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(R)-(-)-N-BENZYL-1-(1-NAPHTHYL)ETHYLAMINE HYDROCHLORIDE Chemical Properties,Usage,Production

Synthesis

82572-04-1

4657-12-9

163831-65-0

GENERAL METHOD: (R)-1-(1-naphthalenyl)ethylamine hydrochloride (1 mmol) was dissolved in methanol (10 mL), and benzaldehyde sodium bisulfite adduct (1.12 mmol) was added. Sodium cyanoborohydride (NaCNBH3, 2.5 mmol) was slowly added to the resulting suspension and the reaction mixture was stirred at room temperature for 20 hours. After completion of the reaction, the solvent was removed by evaporation to obtain the residue. The residue was partitioned with 5N NaOH solution and ethyl acetate (EtOAc). The aqueous phase was further extracted with EtOAc and the organic phases were combined, dried over anhydrous sodium sulfate and the solvent was evaporated to give the crude product. The crude product was dissolved in ether (Et2O) and treated with 0.6N ether-HCl solution. The resulting suspension was cooled at 0°C for 13 h. The precipitated white solid was collected by filtration and dried in vacuum to afford the target product (R)-N-benzyl-1-(naphthalen-1-yl)ethanamine hydrochloride.

References

[1] Tetrahedron Letters, 2014, vol. 55, # 15, p. 2548 - 2550

(R)-(-)-N-BENZYL-1-(1-NAPHTHYL)ETHYLAMINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-(-)-N-BENZYL-1-(1-NAPHTHYL)ETHYLAMINE HYDROCHLORIDE Suppliers

Adamas Reagent, Ltd.
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400-6009262 16621234537
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China
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LABTER PHARMATECH(BEIJING) CO.,LTD
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163831-65-0, (R)-(-)-N-BENZYL-1-(1-NAPHTHYL)ETHYLAMINE HYDROCHLORIDERelated Search:


  • (R)-(-)-N-BENZYL-1-(1-NAPHTHYL)ETHYLAMI&
  • N-benzyl-1-(1-naphthyl)ethylamine hydrochloride
  • (R)-(-)-N-BENZYL-1-(1-NAPHTHYL)ETHYLAMINE HYDROCHLORIDE
  • (R)-N-BENZYL 1-(1-NAPHTHYL)ETHYLAMINE HYDROCHLORIDE
  • (R)-N-[1-(1-NAPHTHYL)ETHYL]BENZYLAMINE HYDROCHLORIDE
  • Cinacalcet Impurity B (HCl salt form)
  • (R)-N-Benzyl-1-(naphthalen-1-yl)ethanamine hydrochloride
  • Cinacalcet Impurity B HCl
  • benzyl-(1-naphthalen-1-yl-ethyl)-amine hydrochloride
  • Cinacalcet Impurity B-HClQ: What is Cinacalcet Impurity B-HCl Q: What is the CAS Number of Cinacalcet Impurity B-HCl Q: What is the storage condition of Cinacalcet Impurity B-HCl Q: What are the applications of Cinacalcet Impurity B-HCl
  • CicalcetImpurityBHCl
  • 163831-65-0
  • C10H7CHCH3NHCH2C6H5HCl
  • C19H19NClH
  • Chiral Resolving Reagents
  • Chiral Resolution Reagents
  • Asymmetric Synthesis