ChemicalBook > CAS DataBase List > 2-Chloromethylbenzimidazole

2-Chloromethylbenzimidazole

Product Name
2-Chloromethylbenzimidazole
CAS No.
4857-04-9
Chemical Name
2-Chloromethylbenzimidazole
Synonyms
2-(chloroMethyl)-1H-benzo[d]iMidazole;2-(CHLOROMETHYL)BENZIMIDAZOLE;TIMTEC-BB S;AKOS BBS-00003999;TIMTEC-BB SBB001845;ASINEX-REAG BAS 05306272;CHLOROMETHYLBENZIMIDAZOLE;2-Chloromethylbenzimidazole,95%;2-CHLOROMETHYL-1H-BENZOIMIDAZOLE;2-(CHLOROMETHYL)-1H-BENZIMIDAZOLE
CBNumber
CB5128718
Molecular Formula
C8H7ClN2
Formula Weight
166.61
MOL File
4857-04-9.mol
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2-Chloromethylbenzimidazole Property

Melting point:
146-148 °C (dec.)(lit.)
Boiling point:
274.83°C (rough estimate)
Density 
1.2387 (rough estimate)
refractive index 
1.5500 (estimate)
storage temp. 
Storage temp. -20°C
pka
11.18±0.10(Predicted)
form 
Powder
color 
Beige to dark yellow
Water Solubility 
Insoluble in water.
InChI
InChI=1S/C8H7ClN2/c9-5-8-10-6-3-1-2-4-7(6)11-8/h1-4H,5H2,(H,10,11)
InChIKey
SPMLMLQATWNZEE-UHFFFAOYSA-N
SMILES
C1(CCl)NC2=CC=CC=C2N=1
CAS DataBase Reference
4857-04-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38
Safety Statements 
26-37/39-36
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C52055
Product name
2-(Chloromethyl)benzimidazole
Purity
96%
Packaging
5g
Price
$55.8
Updated
2025/07/31
Sigma-Aldrich
Product number
C52055
Product name
2-(Chloromethyl)benzimidazole
Purity
96%
Packaging
25g
Price
$60.5
Updated
2025/07/31
Biosynth Carbosynth
Product number
FC03143
Product name
2-Chloromethyl benzimidazole
Packaging
10g
Price
$150
Updated
2021/12/16
Matrix Scientific
Product number
018702
Product name
2-(Chloromethyl)-1H-1,3-benzimidazole
Packaging
5g
Price
$62
Updated
2021/12/16
AK Scientific
Product number
J95938
Product name
2-Chloromethylbenzimidazole
Packaging
25g
Price
$60
Updated
2021/12/16
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2-Chloromethylbenzimidazole Chemical Properties,Usage,Production

Chemical Properties

beige to dark yellow powder

Uses

2-(Chloromethyl)benzimidazole is used as intermediate in pharmaceutical , in organic synthesis .

Synthesis

79-11-8

95-54-5

4857-04-9

GENERAL METHOD: A mixture of o-phenylenediamine (0.1 mol) and chloroacetic acid (0.15 mol) in 100 mL of 5N HCl was heated to reflux and stirred continuously for 3-5 hours. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently neutralized with sodium bicarbonate solution. The precipitate of 2-chloromethylbenzimidazole formed was collected by filtration, washed several times with water and finally dried to obtain the pure product.

References

[1] Collection of Czechoslovak Chemical Communications, 1991, vol. 56, # 6, p. 1358 - 1360
[2] Revue Roumaine de Chimie, 2016, vol. 61, # 1, p. 15 - 22
[3] Oriental Journal of Chemistry, 2017, vol. 33, # 6, p. 3138 - 3143
[4] Heterocycles, 2002, vol. 57, # 8, p. 1423 - 1432
[5] Journal of the Korean Chemical Society, 2010, vol. 54, # 5, p. 589 - 593

2-Chloromethylbenzimidazole Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-Chloromethylbenzimidazole manufacturers

PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD
Product
2-Chloromethylbenzimidazole 4857-04-9
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
500 kgs
Release date
2024-07-08
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-Chloromethylbenzimidazole 4857-04-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
2-Chloromethylbenzimidazole 4857-04-9
Price
US $8.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10tons
Release date
2018-12-23

4857-04-9, 2-ChloromethylbenzimidazoleRelated Search:

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