jolkinolide B

Product Name: jolkinolide B
CAS No.: 37905-08-1
Chemical Name: jolkinolide B
Synonyms: Ritacin-P;Ritacin P;jolkinolide B;Jolkinolide B, 10 mM in DMSO;2'',3'':3,4]phenanthro[3,2-b]furan-9(7aH)-one;(4aR,6aS,7aR,10aR,11aR,11bR,11cR)-4,4,8,11c-tetramethyl-1,2,...;1,4-dibutyl-N-(2,6-dimethylphenyl)piperazine-2-carboxamide,nitrous acid;(4aR,6aS,7aR,10aR,11aR,11bR,11cR)-4,4,8,11c-Tetramethyl-1,2,3,4,4a,5,6,11a,11b,11c-decahydrobis(oxireno)[2',3':1,10a;(4aR,6aS,7aβ,10aR)-1,2,3,4,4aα,5,6,11aβ,11bα,11c-Decahydro-4,4,8,11cβ-tetramethylbisoxireno[1,10a:3,4]phenanthro[3,2-b]furan-9(7aH)-one;Bisoxireno[1,10a:3,4]phenanthro[3,2-b]furan-9(7aH)-one, 1,2,3,4,4a,5,6,11a,11b,11c-decahydro-4,4,8,11c-tetramethyl-, (4aR,6aS,7aR,10aR,11aR,11bR,11cR)-
CBNumber: CB51306403
Molecular Formula: C20H26O4
Formula Weight: 330.42
MOL File: 37905-08-1.mol

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jolkinolide B Property

Melting point:: 213-215℃
Boiling point:: 497.1±45.0 °C(Predicted)
Density: 1.28±0.1 g/cm3 (20 ºC 760 Torr)
storage temp.: -10 to -25°C
solubility: DMSO: 2mg/mL, clear (Warmed)
form: Solid
color: White to off-white
InChI: InChI=1S/C20H26O4/c1-10-12-14-19(22-14)9-6-11-17(2,3)7-5-8-18(11,4)13(19)15-20(12,23-15)24-16(10)21/h11,13-15H,5-9H2,1-4H3/t11-,13+,14-,15-,18-,19+,20-/m1/s1
InChIKey: SOVOCMGDFRGRKF-MCDHERAVSA-N

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML3615
Product name: Jolkinolide B
Purity: ≥95% (HPLC)
Packaging: 5 mg
Price: $77.42
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML3615
Product name: Jolkinolide B
Purity: ≥95% (HPLC)
Packaging: 25 mg
Price: $329
Updated: 2025/07/31

Usbiological

Product number: 300515
Product name: Jolkinolide B
Packaging: 10mg
Price: $468
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb259336
Product name: Jolkinolide B
Purity: 98%
Packaging: 10mg
Price: $499.8
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb259336
Product name: Jolkinolide B
Purity: 98%
Packaging: 20mg
Price: $634.1
Updated: 2021/12/16

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jolkinolide B Chemical Properties,Usage,Production

Uses

Jolkinolide B, a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud, is known to induce apoptosis in cancer cells[1].

Definition

ChEBI: A natural product found in Euphorbia fischeriana.

Biological Activity

Jolkinolide B is a diterpenoid isolated from the dried root of Euphorbia fischeriana steud th at exhibits anticancer, anti-inflammatory and immunomodulatory activities. Jolkinolide B induces apoptosis in numerous human cancer cell lines including breast cancer MDA-MB-231, MCF7, chronic myeloid leukemia K562, leukemic U937 and LNCaP cells. Apparently, it induces apoptosis in mouse melanoma B16F10 cells through downregulation of mRNA expression.

References

[1] Wang, J., Zhou, Y., Bai, X. et al. Jolkinolide B from Euphorbia fischeriana Steud induces apoptosis in human leukemic U937 cells through PI3K/Akt and XIAP pathways. Mol Cells 32, 451–457 (2011). DOI:10.1007/s10059-011-0137-0

jolkinolide B Preparation Products And Raw materials

Raw materials

Preparation Products

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jolkinolide B Suppliers

China 125 United States 10 Global 135

Nanjing Dasf Biotechnology Co., Ltd.

Tel: 025-025-+86-02585846866 +86-18094231287
Fax: 025-83144123
Email: 1773155960@qq.com
Country: China
ProdList: 1992
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Huzhou ZhanShu Biotechnology Co.,Ltd

Tel: 0572-8889530 18167260939
Email: zsubio@163.com
Country: China
ProdList: 392
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Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11705
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Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4747
Advantage: 58

Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
Fax: 028-86757656
Email: 800078821@qq.com
Country: China
ProdList: 9718
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Chengdu Biopurify Phytochemicals Ltd.

Tel: +86-028-82633397 18982077548
Fax: +86-28-82633165
Email: cwb1@biopurify.cn
Country: China
ProdList: 2376
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Chengdu Climax Biotech Co., Ltd.

Tel: 028-83311324 1278112614
Fax: 028-83311324
Email: climaxbiotech@gmail.com
Country: China
ProdList: 925
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Shanghai Ruji Biology Technology Co., Ltd.

Tel: +86-21-65211385-8001 36031160
Fax: +86-21-65211385-8004
Email: sales@shruji.com
Country: China
ProdList: 3224
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Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3988
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AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2782
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View Lastest Price from jolkinolide B manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Jolkinolide B 37905-08-1
Price: US $0.00/mg
Min. Order: 20mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-03-16

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jolkinolide B

(4aR,6aS,7aβ,10aR)-1,2,3,4,4aα,5,6,11aβ,11bα,11c-Decahydro-4,4,8,11cβ-tetramethylbisoxireno[1,10a:3,4]phenanthro[3,2-b]furan-9(7aH)-one

1,4-dibutyl-N-(2,6-dimethylphenyl)piperazine-2-carboxamide,nitrous acid

Bisoxireno[1,10a:3,4]phenanthro[3,2-b]furan-9(7aH)-one, 1,2,3,4,4a,5,6,11a,11b,11c-decahydro-4,4,8,11c-tetramethyl-, (4aR,6aS,7aR,10aR,11aR,11bR,11cR)-

(4aR,6aS,7aR,10aR,11aR,11bR,11cR)-4,4,8,11c-tetramethyl-1,2,...

Ritacin P

Ritacin-P

Jolkinolide B, 10 mM in DMSO

(4aR,6aS,7aR,10aR,11aR,11bR,11cR)-4,4,8,11c-Tetramethyl-1,2,3,4,4a,5,6,11a,11b,11c-decahydrobis(oxireno)[2',3':1,10a

2'',3'':3,4]phenanthro[3,2-b]furan-9(7aH)-one

37905-08-1

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract