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riddelline

Product Name
riddelline
CAS No.
23246-96-0
Chemical Name
riddelline
Synonyms
RIDELLINE;Aids020850;riddelline;RIDDELLIINE;Aids-020850;13,19-Didehydro-12,18-dihydroxysenecionan-11,16-dione;[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-(hydroxymethyl)-5-methylene-, (3Z,6S,14aR,14bR)-
CBNumber
CB51327734
Molecular Formula
C18H23NO6
Formula Weight
349.38
MOL File
23246-96-0.mol
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riddelline Property

Melting point:
197.5°C (rough estimate)
Boiling point:
483.56°C (rough estimate)
Density 
1.2966 (rough estimate)
refractive index 
1.5740 (estimate)
pka
11.62±0.20(Predicted)
IARC
2B (Vol. 10, Sup 7, 82) 2002
EPA Substance Registry System
Riddelline (23246-96-0)
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Safety

RIDADR 
1544
HazardClass 
6.1(b)
PackingGroup 
III
Hazardous Substances Data
23246-96-0(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Medical Isotopes, Inc.
Product number
48587
Product name
Riddelline
Packaging
10mg
Price
$2200
Updated
2021/12/16
Arctom
Product number
CFN00421
Product name
Riddelline
Packaging
5mg
Price
$418
Updated
2021/12/16
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riddelline Chemical Properties,Usage,Production

Chemical Properties

Colorless to yellowish crystalline solid. Starts turning brown at approximately 165℃; turns blackish- brown at 187℃.

Uses

Riddelliine-containing plants are not used for food in the United States, and riddelliine and riddelliine N-oxide have no known commercial uses. However, the riddelliine-containing plant Senecio longilobus has been used in medicinal herb preparations in the United States, and S. jacobaea and S. vulgaris, both of which have been shown to contain riddelliine, are used in medicinal preparations in other parts of the world (Mattocks 1986).

Definition

ChEBI: A macrolide that is 13,19-didehydrosenecionan bearing two additional hydroxy substituents at positions 12 and 18 as well as two additional oxo groups at positions 11 and 16.

General Description

Colorless to off-white crystalline solid. Starts turning brown at approximately 329°F; is blackish-brown at melting point.

Air & Water Reactions

Exposure to light and air can cause gradual oxidation. Insoluble in water.

Reactivity Profile

riddelline reacts readily with oxidizing agents (slowly with atmospheric oxygen). On contact with bases, hydrolysis will probably occur .

Fire Hazard

Flash point data for riddelline are not available; however, riddelline is probably combustible.

Potential Exposure

Riddelline is a natural alkaloid product used a laboratory chemical and reference standard.

Carcinogenicity

Riddelliine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals and supporting data from studies on mechanisms of carcinogenesis.

Shipping

UN1544 Alkaloids, solid, n.o.s. or Alkaloid salts, solid, n.o.s. poisonous, Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

Incompatibilities

Riddelline is sensitive to light, air, and heat, causing oxidation; reacts slowly with atmospheric oxygen. This chemical is probably combustible; dust mixed with air may be explosive. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, and epoxides. Contact with alkalis and bases may cause hydrolysis.

Waste Disposal

It is inappropriate and possi- bly dangerous to the environment to dispose of expired or waste product such as lab chemicals by flushing them down the toilet or discarding them to the trash. Larger quantities shall carefully take into consideration applicable EPA, and FDA regulations. If possible return the lab che- micals to the manufacturer for proper disposal being careful to properly label and securely package the material. Alternatively, the waste lab chemicals shall be labeled, securely packaged and transported by a state licensed medi- cal waste contractor to dispose by burial in a licensed haz- ardous or toxic waste landfill or incinerator.

riddelline Preparation Products And Raw materials

Raw materials

Preparation Products

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riddelline Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7887
Advantage
56
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Wuhan ChemFaces Biochemical Co., Ltd.
Tel
18607101326 15172504745
Fax
+86-27-84254680
Email
aileen@chemfaces.com
Country
China
ProdList
7057
Advantage
55
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
Shenzhen Regent Biochemical Technology Co., Ltd.
Tel
0755-0755-85201366 18938635012
Fax
0755-85201366
Email
sales@regentsciences.com
Country
China
ProdList
9353
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57423
Advantage
58
Wuxi Helen Biotechnology Co., Ltd.,
Tel
0510-85629785 18013409632
Fax
0510-85625359
Email
sales@reading-chemicals.com
Country
China
ProdList
14081
Advantage
58
Changzhou Furuisi Biotechnology Co., Ltd
Tel
0519-85524369
Email
3477467573@qq.com
Country
China
ProdList
8617
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58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29774
Advantage
58

23246-96-0, riddellineRelated Search:


  • riddelline
  • RIDELLINE
  • [1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-(hydroxymethyl)-5-methylene-, (3Z,6S,14aR,14bR)-
  • RIDDELLIINE
  • 13,19-Didehydro-12,18-dihydroxysenecionan-11,16-dione
  • Aids020850
  • Aids-020850
  • 23246-96-0