irisolidone
- Product Name
- irisolidone
- CAS No.
- 2345-17-7
- Chemical Name
- irisolidone
- Synonyms
- irisoidone;irisolidone;4'-Methoxytectorigenin;4'-O-Methyltectorigenin;5,7-Dihydroxy-6,4'-dimethoxyisoflavon;5,7-dihydroxy-6-methoxy-3-(4-methoxyphenyl)-4H-chromen-4-one;5,7-Dihydroxy-6-methoxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 5,7-dihydroxy-6-methoxy-3-(4-methoxyphenyl)-;Chloride Channel,Cl? Channels,Inhibitor,hepatoprotective,inhibit,VRAC,Irisolidone
- CBNumber
- CB51330783
- Molecular Formula
- C17H14O6
- Formula Weight
- 314.29
- MOL File
- 2345-17-7.mol
irisolidone Property
- Melting point:
- 190-191 °C
- Boiling point:
- 565.5±50.0 °C(Predicted)
- Density
- 1.402±0.06 g/cm3(Predicted)
- storage temp.
- 4°C, protect from light
- solubility
- Chloroform (Slightly), DMSO (Slightly)
- form
- Solid
- pka
- 6.48±0.20(Predicted)
- color
- Off-White to Pale Yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- SY232783
- Product name
- 5,7-Dihydroxy-6-methoxy-3-(4-methoxyphenyl)-4H-chromen-4-one
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $619.09
- Updated
- 2021/12/16
- Product number
- AS671770
- Product name
- Irisolidone
- Purity
- 98%
- Packaging
- 100mg
- Price
- $787
- Updated
- 2021/12/16
irisolidone Chemical Properties,Usage,Production
Description
Irisolidone is a hydrolyzed product of kudzurin. Studies have shown that it can significantly dilate coronary arteries, cerebral arteries and peripheral blood vessels and microvessels, and can reduce vascular resistance, cholesterol and blood viscosity.
Chemical Properties
Light yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from kudzu.
Uses
Irisolidone has anti-inflammatory, antioxidant, antibacterial, anti-tumor, estrogen-like effects, and protects liver damage caused by alcoholism.
Definition
ChEBI: Irisolidone is a member of 4'-methoxyisoflavones.
Biological Activity
Irisolidone is the main isoflavone in pueraria. Irisolidone has strong hepatoprotective activity. It has a highly effective blocking effect on the anion channel VRAC.
in vitro
Irisolidone shows the high efficacy for Volume-regulated anion channels (VRAC) blockade with an IC 50 of 9.8 μM in HEK293 cells.
It can inhibit endothelial cell proliferation.
irisolidone Preparation Products And Raw materials
Raw materials
Preparation Products
irisolidone Suppliers
- Tel
- +1-+1(833)-552-7181
- sales@aladdinsci.com
- Country
- United States
- ProdList
- 52925
- Advantage
- 58
- Tel
- support@targetmol.com
- Country
- United States
- ProdList
- 38632
- Advantage
- 58
- Tel
- --
- Fax
- --
- sales@medchemexpress.com
- Country
- United States
- ProdList
- 6398
- Advantage
- 58
- Tel
- --
- Fax
- --
- sales@qualityphytochemicalsllc.com
- Country
- United States
- ProdList
- 1461
- Advantage
- 50