2-MERCAPTOPYRIDINE N-OXIDE Property

Melting point:

70-72 °C

Boiling point:

109 °C

Density 

1.22

form 

Granular Crystalline Powder

color 

Off-white to yellow

Merck 

14,7994

Safety

Hazard Codes 

Xn

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

RTECS 

UT9000000

F 

8-10-13-23

TSCA 

Yes

HS Code 

29333999

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

2-MERCAPTOPYRIDINE N-OXIDE Chemical Properties,Usage,Production

Chemical Properties

OFF-WHITE TO YELLOWISH GRANULAR CRYST. POWDER

Preparation

A solution of 60 gm (0.284) of 2-bromopyridine N-oxide hydrochloride is neutralized with 25% aqueous sodium hydroxide. In a well-ventilated hood, to this solution, heated with stirring on a steam bath, is added dropwise over a 1-hr period a solution of 32 gm (0.57 mole) of sodium hydrogen sulfide in 150 ml of water. After the addition has been com­pleted, heating is continued for 0.5 hr. The reaction mixture is cooled, filtered, and acidified with 6 Ν hydrochloric acid to afford 24 gm (67%), m.p. 65-68°C. Upon recrystallization from aqueous ethanol, the melting point is raised to 68-70°C.
Similar results were obtained when an equivalent quantity of sodium sulfide was substituted for sodium hydrogen sulfide.