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LOCHNERINE

Product Name
LOCHNERINE
CAS No.
522-47-4
Chemical Name
LOCHNERINE
Synonyms
LOCHNERINE;Lochenerine;Luo Ke alkali;(+)-Lochnerine;(+)-Lochenerine;10-O-Methylsarpagine;10-Methoxynormacusine B;10-Methoxysarpagan-17-ol;Sarpagan-17-ol, 10-methoxy-;6,10-Methanoindolo[3,2-b]quinolizine-11-methanol,9-ethylidene-5,6,8,9,10,11,11a,12-octahydro-2-methoxy-,(6S,7R,9E,10R,11R,11aS)-
CBNumber
CB51442961
Molecular Formula
C20H24N2O2
Formula Weight
324.422
MOL File
522-47-4.mol
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LOCHNERINE Property

Melting point:
202.5-203.5°C
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Arctom
Product number
CFN98852
Product name
Lochnerine
Packaging
5mg
Price
$463
Updated
2021/12/16
Crysdot
Product number
CD32001115
Product name
Lochnerine
Purity
95+%
Packaging
5mg
Price
$730
Updated
2021/12/16
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LOCHNERINE Chemical Properties,Usage,Production

Description

This carboline alkaloid has been obtained from Lochnera rosea and is also present in curare (Strychnos toxifera). Early preparations have been designated Alkaloid 'C' and C-Alkaloid T. It has [α]D + 56° (pyridine) or + n° (EtOH) and forms a crystalline picrate with a double melting point of 177-9°C and 243-5°C (dec.). The methiodide is identical with lochneram iodide, m.p. 235-8°C. A characteristic p-toluenesulphonyl derivative has been prepared, m.p. 153-4°C. One primary alcoholic hydroxyl is present and the alkaloid yields the O-acetate as colourless needles, m.p. 243°C; [α]D - 5.6° ± 3.0° (c 0.36, pyridine). The structure is that of O-methylsarpagine.

References

Janot, LeMen., Cornpt. rend., 243, 1789 (1956)
Mors et at., Chern. Ind., 173 (1956)
Arnold et at., Helv. Chirn. Acta, 40, 705 (1957)
Arnold et al., ibid, 41, 1505 (1958)
Karrer et at., Angew. Chern., 70,644 (1958)

LOCHNERINE Preparation Products And Raw materials

Raw materials

Preparation Products

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522-47-4, LOCHNERINERelated Search:


  • LOCHNERINE
  • (+)-Lochenerine
  • 10-Methoxysarpagan-17-ol
  • Lochenerine
  • 10-Methoxynormacusine B
  • 10-O-Methylsarpagine
  • Luo Ke alkali
  • 6,10-Methanoindolo[3,2-b]quinolizine-11-methanol,9-ethylidene-5,6,8,9,10,11,11a,12-octahydro-2-methoxy-,(6S,7R,9E,10R,11R,11aS)-
  • Sarpagan-17-ol, 10-methoxy-
  • (+)-Lochnerine
  • 522-47-4