ChemicalBook > CAS DataBase List > METHYL 2-AMINO-5-METHOXYBENZOATE

METHYL 2-AMINO-5-METHOXYBENZOATE

Product Name
METHYL 2-AMINO-5-METHOXYBENZOATE
CAS No.
2475-80-1
Chemical Name
METHYL 2-AMINO-5-METHOXYBENZOATE
Synonyms
Methyl 6-amino-m-anisate;Methyl 5-methoxyanthranilate;Methyl2-amino-5-methoxybenzoate,96%;2-Amino-5-methoxybenzoic acid methyl ester;Benzoic acid, 2-aMino-5-Methoxy-, Methyl ester
CBNumber
CB51486729
Molecular Formula
C9H11NO3
Formula Weight
181.19
MOL File
2475-80-1.mol
More
Less

METHYL 2-AMINO-5-METHOXYBENZOATE Property

Melting point:
37-38℃
Boiling point:
298.8±20.0 °C(Predicted)
Density 
1.179±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
2.70±0.10(Predicted)
Appearance
Light brown to brown Solid
Water Solubility 
Slightly Soluble (1.1 g/L) (25°C) in water.
More
Less

Safety

HS Code 
2922500090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

TRC
Product number
M328730
Product name
Methyl2-Amino-5-methoxybenzoate
Packaging
10g
Price
$330
Updated
2021/12/16
Apolloscientific
Product number
OR912063
Product name
Methyl2-amino-5-methoxybenzoate
Purity
98%
Packaging
1g
Price
$182
Updated
2021/12/16
Apolloscientific
Product number
OR912063
Product name
Methyl2-amino-5-methoxybenzoate
Purity
98%
Packaging
5g
Price
$573
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0122339
Product name
METHYL 2-AMINO-5-METHOXYBENZOATE
Purity
95.00%
Packaging
1G
Price
$721.57
Updated
2021/12/16
Apolloscientific
Product number
OR912063
Product name
Methyl2-amino-5-methoxybenzoate
Purity
98%
Packaging
10g
Price
$928
Updated
2021/12/16
More
Less

METHYL 2-AMINO-5-METHOXYBENZOATE Chemical Properties,Usage,Production

Uses

It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs.

Synthesis

2327-45-9

2475-80-1

The general procedure for the synthesis of methyl 2-amino-5-methoxybenzoate from methyl 5-methoxy-2-nitrobenzoate was as follows: methyl 5-methoxy-2-nitrobenzoate (1.60 g, 7.58 mmol) was dissolved in ethyl acetate (14 mL), and 10% palladium-carbon catalyst (containing 50% water, 320 mg) was added. The reaction was stirred at 20-25°C for 3 hours under hydrogen atmosphere (0.25 MPa). Upon completion of the reaction, the palladium-carbon catalyst was removed by filtration and the solvent was removed by distillation under reduced pressure. The resulting crude product was purified by silica gel column chromatography with hexane/ethyl acetate (10:1 to 5:1) as eluent to afford methyl 2-amino-5-methoxybenzoate (1.29 g, 94% yield). The product was characterized by 1H-NMR (CDCl3), δ: 3.76 (3H, s), 3.88 (3H, s), 5.37 (2H, br), 6.63 (1H, d, J = 8.8 Hz), 6.95 (1H, dd, J = 8.8, 3.1 Hz), 7.35 (1H, d, J = 3.1 Hz).

References

[1] Patent: EP1724268, 2006, A1. Location in patent: Page/Page column 50
[2] Synlett, 2016, vol. 27, # 8, p. 1237 - 1240
[3] Patent: EP1844768, 2007, A1. Location in patent: Page/Page column 25
[4] Patent: CN106478548, 2017, A. Location in patent: Paragraph 0089; 0090; 0121; 0122; 0137; 0138
[5] Australian Journal of Chemistry, 1972, vol. 25, p. 2621 - 2629

METHYL 2-AMINO-5-METHOXYBENZOATE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

METHYL 2-AMINO-5-METHOXYBENZOATE Suppliers

China 95 India 3 Switzerland 1 United Kingdom 2 United States 6 Global 107
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
Shanghai Harvest Chemical Industrial Co., Ltd.
Tel
021-31038972,31038973 17321035817
Fax
+86-21-51385350
Email
sales@harvest-chem.com
Country
China
ProdList
2816
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Beijing Eternalchem Co,. Ltd.
Tel
010-59484199 18611897322
Email
sales@eternalchem.com
Country
China
ProdList
4383
Advantage
60
Hangzhou Sage Chemical Co., Ltd.
Tel
+86057186818502 13588463833
Fax
Pls mail us for more information!
Email
info@sagechem.com
Country
China
ProdList
10266
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
SuZhou ShiYa Biopharmaceuticals, Inc.
Tel
86(512)5235 8471 17715136450
Fax
86(512)5235 6881
Email
sales@shiyabiopharm.com
Country
China
ProdList
4169
Advantage
58
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9546
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Mashilabs (Shanghai) Co.,Ltd.
Tel
19916721580
Fax
QQ：3154870176
Email
mafarm@126.com
Country
China
ProdList
4542
Advantage
58
Tianjin Anhao Biological Technology Co., Ltd.
Tel
Email
sales@ahpharmatech.com
Country
China
ProdList
5734
Advantage
55
Nanjing Derno Pharmaceutical Technology Co., Ltd.
Tel
025-86957866 13952093866
Fax
025-68661287
Email
sales@dernopharm.com
Country
China
ProdList
932
Advantage
58
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Chengdu Research Accelerators Technology Co., Ltd.
Tel
028-64353063
Fax
028-64353063 QQ:784253935
Email
reacchemical@163.com
Country
China
ProdList
5253
Advantage
58
Zhengzhou Alfachem Co., Ltd.
Tel
0371-53765687 18937137882
Fax
QQ:2885373884
Email
2853979813@qq.com
Country
China
ProdList
7991
Advantage
55
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9951
Advantage
56
ShangHai Angti Biotechnology Co., Ltd.
Tel
13764913901
Fax
-
Email
info@angtibio.com
Country
China
ProdList
4985
Advantage
55
Codow Chemical Co.,Ltd.
Tel
18620099427
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
6687
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Chengdu Huachun Technology Co., Ltd
Tel
400-1166-196 15982826727
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
14603
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shanghai CR Corporation Limited
Tel
13062833949; 4006653949 4006653949
Fax
QQ: 2136646215
Email
fred.wen@crcorporation.cn
Country
China
ProdList
9756
Advantage
58
Nanijing m&m biotechnology Co. ,Ltd.
Tel
025-87782433 18021532344
Fax
025-87782433
Email
1345332203@qq.com
Country
China
ProdList
4134
Advantage
58
Hangzhou Molcore Biopharmatech Co.,Ltd
Tel
400-711-5280 86-571-81025280
Fax
86-571-85806285
Email
sales@molcore.com
Country
China
ProdList
9967
Advantage
58
Shanghai Zhen Li Biological Technology Co., Ltd
Tel
021-16621358918; 18516310516
Fax
13045646768
Email
zhenlipharma888@163.com
Country
China
ProdList
19035
Advantage
58
Capot Chemical Co.,Ltd.
Tel
+86-（0）57185586718; +8613336195806
Fax
+86-571-85864795
Email
sales@capot.com
Country
China
ProdList
29735
Advantage
60
Suzhou Nuoouman Biological Technology Co., Ltd.
Tel
15026866316
Email
180642609@qq.com
Country
China
ProdList
4967
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 400821072
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
25000
Advantage
58
Suzhou Xiya Pharmaceutical Co., Ltd.
Tel
0512-87819718 18912655635
Email
2587879032@qq.com
Country
China
ProdList
1403
Advantage
58
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400-6387771-6039 18920764717
Email
sales@heowns.com
Country
China
ProdList
23771
Advantage
60
Jinan Yaoyan Pharmaceutical Co., Ltd.
Tel
Fax
-
Email
jnyaoyan@163.com
Country
China
ProdList
3069
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52687
Advantage
58
wuhan Dekray Biomedical Technology Co.,Ltd
Tel
027-69573188 18221423799
Email
1503407886@qq.com
Country
China
ProdList
1439
Advantage
58
Xinyi Kangda Biological Technology Co., Ltd.
Tel
13013943931 15152133928
Email
xinyikangda@163.com
Country
China
ProdList
610
Advantage
58
Jinan Carbotang Biotech Co.,Ltd.
Tel
+8615866703830
Email
figo.gao@foxmail.com
Country
China
ProdList
8497
Advantage
58
Xinyi Kaiwu Chemical Technology Co., Ltd.
Tel
0516-0516-88997009 18651776937
Email
4164357@qq.com
Country
China
ProdList
3204
Advantage
58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.
Tel
meitaochem@126.com
Email
meitaochem@126.com
Country
China
ProdList
19103
Advantage
58
CR Corporation Limited
Tel
+8613062833949
Email
fred.wen@crcorporation.cn
Country
China
ProdList
8645
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
+86-0551-65418671 +8618949823763
Fax
0551-65418697
Email
sales@tnjchem.com
Country
China
ProdList
34563
Advantage
58
Changzhou Helios Biomedical Science and Technology Co.,LTD.
Tel
+8618961213068
Email
gaoxue@czhelios.com
Country
China
ProdList
512
Advantage
58
CD Chemical Group Limited
Tel
+8615986615575
Fax
0086-13651442114
Email
info@codchem.com
Country
China
ProdList
20342
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
+86-0571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52846
Advantage
58
Win-Win chemical CO., Limited
Tel
+86-0086-577-64498589 +86-15355981851
Fax
0086-577-56994596
Email
sales@win-winchemical.com
Country
China
ProdList
14359
Advantage
58
HUNAN CHEMFISH SCIENTIFIC CO.,LTD
Tel
+86-0731-85567275 13298656710
Fax
QQ:3554193828
Email
sales05@chemfish.com
Country
China
ProdList
7448
Advantage
58
Chemwill Asia Co.,Ltd.
Tel
86-21-51086038
Fax
86-21-51861608
Email
chemwill_asia@126.com
Country
CHINA
ProdList
23912
Advantage
58
Zhejiang Lianshuo Biotechnology Co., Ltd.
Tel
18616526224
Email
lianshuo@vip.126.com
Country
China
ProdList
9607
Advantage
58
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Email
sales@accelachem.com
Country
China
ProdList
10467
Advantage
58
Chengdu Feibo Pharm Technology Co., Ltd
Tel
+86 028-84641798 15982321820
Email
abby@arkpharm.com
Country
China
ProdList
10000
Advantage
58
More
Less

View Lastest Price from METHYL 2-AMINO-5-METHOXYBENZOATE manufacturers

Career Henan Chemical Co
Product
METHYL 2-AMINO-5-METHOXYBENZOATE 2475-80-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2019-07-11

2475-80-1, METHYL 2-AMINO-5-METHOXYBENZOATERelated Search:

Methyl 2-amino-4,5-dimethoxybenzoate Methyl 2-nitro-3,4,5-trimethoxybenzoate ACIFLUORFEN METHYL ESTER ETHYL 2-AMINO-4,5-DIMETHOXYBENZOATE Methyl 4,5-dimethoxy-2-nitrobenzoate Methyl 2-amino-3,4,5-trimethoxybenzoate METHYL 5-METHOXY-2-NITROBENZOATE ETHYL 4,5-DIMETHOXY-2-NITROBENZOATE Bifenox 2-Amino-5-methoxybenzoic acid 6,7-DIMETHOXY-2-(3-NITROPHENYL)-4H-3,1-BENZOXAZIN-4-ONE Tritoqualine METHYL 2-AMINO-4,5-DIETHOXYBENZOATE CBI-BB ZERO/005500 458L 6,7-DIMETHOXY-2-METHYL-BENZO[D][1,3]OXAZIN-4-ONE RARECHEM AL BI 0176 6,7-DIMETHOXY-2-(4-METHYLPHENYL)-4H-3,1-BENZOXAZIN-4-ONE

  • Benzoic acid, 2-aMino-5-Methoxy-, Methyl ester
  • 2-Amino-5-methoxybenzoic acid methyl ester
  • Methyl 5-methoxyanthranilate
  • Methyl 6-amino-m-anisate
  • Methyl2-amino-5-methoxybenzoate,96%
  • 2475-80-1