5'-DEOXYADENOSINE

Description

Product Name: 5'-DEOXYADENOSINE
CAS No.: 4754-39-6
Chemical Name: 5'-DEOXYADENOSINE
Synonyms: 5′-dAdo;5'-DEOXYADENOSINE;5’-deoxy-adenosin;5'-DEOXYADENOSINE;Adenosine, 5'-deoxy-;2'-Deoxycytidine Monohydrate(2'-dC ? H?O);9-(5-Deoxy-β-D-ribofuranosyl)-9H-purine-6-amine;6-Amino-9-(5-deoxy-β-D-ribofuranosyl)-9H-purine;(2R,3R,4R,5R)-2-(6-aminopurin-9-yl)-5-methyl-oxolane-3,4-diol;(2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-methyltetrahydrofuran-3,4-diol
CBNumber: CB5163003
Molecular Formula: C10H13N5O3
Formula Weight: 251.24
MOL File: 4754-39-6.mol

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5'-DEOXYADENOSINE Property

Melting point:: 210-212 °C
Boiling point:: 595.0±60.0 °C(Predicted)
Density: 1.93±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.20 mg/ml; DMSO: 15 mg/ml
form: A crystalline solid
pka: 13.29±0.70(Predicted)
InChIKey: XGYIMTFOTBMPFP-KQYNXXCUSA-N

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Safety

WGK Germany: 3
RTECS: AU7358650

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D1771
Product name: 5′-Deoxyadenosine
Purity: methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase substrate
Packaging: 25mg
Price: $264
Updated: 2024/03/01

Cayman Chemical

Product number: 29619
Product name: 5''-Deoxyadenosine
Packaging: 10mg
Price: $40
Updated: 2024/03/01

Cayman Chemical

Product number: 29619
Product name: 5''-Deoxyadenosine
Packaging: 250mg
Price: $541
Updated: 2024/03/01

Cayman Chemical

Product number: 29619
Product name: 5''-Deoxyadenosine
Packaging: 50mg
Price: $158
Updated: 2024/03/01

Cayman Chemical

Product number: 29619
Product name: 5''-Deoxyadenosine
Packaging: 100mg
Price: $296
Updated: 2024/03/01

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5'-DEOXYADENOSINE Chemical Properties,Usage,Production

Description

5'-Deoxyadenosine is an oxidized nucleoside found in the urine of normal subjects. Oxidized nucleosides represent excellent biomarkers for determining the extent of damage in genetic material, which has long been of interest in understanding the mechanism of aging, neurodegenerative diseases, and carcinogenesis.

Uses

5′-Deoxyadenosine has been used:

as a standard in mass spectroscopy
as an inhibitor for screening thymidine phosphorylase activity
as a substrate in 5′-Deoxyadenosine deaminase (DadD) assay

Definition

ChEBI: A 5'-deoxyribonucleoside compound having adenosine as the nucleobase.

Biochem/physiol Actions

5′-Deoxyadenosine is a substrate for the enzyme methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase in microbes. 5′-Deoxyadenosine is a byproduct of cleavage of S-adenosylmethionine (SAM). High levels of 5′-Deoxyadenosine inhibits SAM dependent enzymes. It also inhibits biotin synthase (BioB) and lipoyl synthase (LipA) enzymes.

5'-DEOXYADENOSINE Preparation Products And Raw materials

Raw materials

Preparation Products

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5'-DEOXYADENOSINE Suppliers

Canada 1 China 44 Germany 1 Switzerland 1 United Kingdom 2 United States 7 USA 1 Global 57

Fuyang Ziyi Biological Pharmaceutical Co., Ltd.

Tel: 19308655899
Fax: -
Email: 2677609105@qq.com
Country: China
ProdList: 461
Advantage: 58

Hangzhou Sage Chemical Co., Ltd.

Tel: +86057186818502 13588463833
Fax: Pls mail us for more information!
Email: info@sagechem.com
Country: China
ProdList: 10269
Advantage: 58

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9442
Advantage: 58

Zouping Mingxing Chemical Co.,Ltd.

Tel: 86-13605431940 13605431940
Fax: 0086-0543-2240079
Email: zpmxchemical@126.com
Country: China
ProdList: 2002
Advantage: 62

Hubei XinyuanShun Chemical Co., Ltd.

Tel: 13971561712, 13995564702, 027-50664929
Fax: 027-50664927
Email: hbeixys2001@163.com
Country: China
ProdList: 3123
Advantage: 55

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 15878
Advantage: 55

Hangzhou J&H Chemical Co., Ltd.

Tel: +86-571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 10015
Advantage: 53

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51471
Advantage: 80

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131981
Advantage: 58

Anhui kuer Bioengineering Co., Ltd

Tel: 0551-65171243 13810511747
Email: kuer@kuerhuaxue.com
Country: China
ProdList: 2997
Advantage: 55

4754-39-6, 5'-DEOXYADENOSINERelated Search:

N6,N6-DIMETHYLADENOSINE ADENOSINE 2' -& 3'-MONOPHOSPHATE FREE 2',3'-O-Isopropylideneadenosine 5'-Tosyladenosine 5'-(Methylthio)-5'-deoxyadenosine N6-BENZYLADENOSINE 2-Chloroadenosine Cyclic AMP Vidarabine Adenosine 5'-monophosphate monohydrate Bucladesine sodium 3'-ADENYLIC ACID 8-BROMOADENOSINE ADENOSINE-2':3'-CYCLIC MONOPHOSPHATE, SODIUM SALT 5'-IODO-5'-DEOXYADENOSINE N6-BENZOYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYADENOSINE DMT-dA(bz) Phosphoramidite N6-BZ-2'-DEOXYADENOSINE

5’-deoxy-adenosin

(2R,3R,4R,5R)-2-(6-aminopurin-9-yl)-5-methyl-oxolane-3,4-diol

6-Amino-9-(5-deoxy-β-D-ribofuranosyl)-9H-purine

9-(5-Deoxy-β-D-ribofuranosyl)-9H-purine-6-amine

5'-DEOXYADENOSINE

Adenosine, 5'-deoxy-

5′-dAdo

2'-Deoxycytidine Monohydrate(2'-dC ? H?O)

5'-Deoxyadenosine methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase substrate

(2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-methyltetrahydrofuran-3,4-diol

inhibit,5'DEOXYADENOSINE,5'-Deoxyadenosine,Endogenous Metabolite,Inhibitor,Orthopoxvirus,5' DEOXYADENOSINE

5'-DEOXYADENOSINE

4754-39-6

BioChemical

Biochemicals and Reagents

Nucleoside Analogs

Nucleosides, Nucleotides, Oligonucleotides

Biochemicals and Reagents

Nucleoside Analogs

Nucleosides, Nucleotides, Oligonucleotides