6-Acetamidohexanoic acid
- Product Name
- 6-Acetamidohexanoic acid
- CAS No.
- 57-08-9
- Chemical Name
- 6-Acetamidohexanoic acid
- Synonyms
- AACA;CY 153;AceMin;Plastenan;Acexamic Acid;Acetaminocaproic acid;6-Acetamidocaproic acid;e-Acetamidocaproic Acid;6-acetylaminocaproicacid;6-ACETAMINOHEXANOIC ACID
- CBNumber
- CB5168240
- Molecular Formula
- C8H15NO3
- Formula Weight
- 173.21
- MOL File
- 57-08-9.mol
6-Acetamidohexanoic acid Property
- Melting point:
- 102-104 °C(lit.)
- Boiling point:
- 303.86°C (rough estimate)
- Density
- 1.1599 (rough estimate)
- refractive index
- 1.4590 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO (Sparingly), Methanol (Slightly)
- pka
- 4.75±0.10(Predicted)
- form
- Solid
- color
- White to Off-White
- Merck
- 14,45
- InChI
- InChI=1S/C8H15NO3/c1-7(10)9-6-4-2-3-5-8(11)12/h2-6H2,1H3,(H,9,10)(H,11,12)
- InChIKey
- WDSCBUNMANHPFH-UHFFFAOYSA-N
- SMILES
- C(O)(=O)CCCCCNC(C)=O
- LogP
- -0.500 (est)
- CAS DataBase Reference
- 57-08-9(CAS DataBase Reference)
Safety
- Safety Statements
- 24/25
- WGK Germany
- 3
- HS Code
- 29241900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H317May cause an allergic skin reaction
H319Causes serious eye irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A158410
- Product name
- 6-AcetamidohexanoicAcid
- Packaging
- 10g
- Price
- $110
- Updated
- 2021/12/16
- Product number
- A158410
- Product name
- 6-AcetamidohexanoicAcid
- Packaging
- 2.5g
- Price
- $65
- Updated
- 2021/12/16
- Product number
- A158410
- Product name
- 6-AcetamidohexanoicAcid
- Packaging
- 100g
- Price
- $340
- Updated
- 2021/12/16
- Product number
- FA45117
- Product name
- 6-Acetamidohexanoic acid
- Packaging
- 500g
- Price
- $190
- Updated
- 2021/12/16
- Product number
- FA45117
- Product name
- 6-Acetamidohexanoic acid
- Packaging
- 1kg
- Price
- $300
- Updated
- 2021/12/16
6-Acetamidohexanoic acid Chemical Properties,Usage,Production
Chemical Properties
WHITE POWDER
Originator
Acexamic acid ,Flamma
Uses
wound healing agent
Uses
6-Acetamidohexanoic acid is used after oral administration of an antiulcer agent, zinc acexamate (ZAC) for treatment of gastric ulcer or small bowel inflammation.
Definition
ChEBI: Acexamic acid is a medium-chain fatty acid.
Manufacturing Process
400 L of demineralized water, 5.0 kg of calcium hydroxide, and 155.0 kg
(1000 moles) of acetyl-caprolactame are introduced under stirring and at a
temperature of about 25°C into a 1000 L stainless double walled reactor.
The temperature is raised to 30°C. 75.0 kg of calcium hydroxide are
introduced stepwise in the form of successive amounts of 2.0 kg each in the
medium, under stirring and at a temperature adjusted and maintained 25°-
30°C through external cooling, in a manner such that the time required to
introduce into the reactor the whole amount of calcium hydroxide
approximates 1.5 h. When the stirring is stopped, the pH is about 7.5-7.8.
The obtained mixture is stirred continuously at a temperature of 30°C during
14 h. At the end of this operation the pH is again adjusted at a value 7.5-7.8.
The hydrolysate is filtered on a 60 x 60 pressfilter comprising 6 compartments
and equipped with fabrics of the polyester known under the designation
TERGAL which have been previously coated with a suspension of a cellulose
commercialized under the trademark SOLKA FLOX BW20. The duration of
filtration is of 1.5 h. 580 L of the filtrate are recovered and subjected to a
concentration under reduced pressure in an evaporator the volume of which is
of 750 L, at a distillation temperature ranging from 45°-50°C under a reduced
pressure of 10-15 Torr.
The operation is ran until concentration of the solution to 280 L, the
concentrated solution being then left standing. The crystallisation is already
considerable 2 h after the end of the operation of concentration.
Crystallisation is ended after 16-24 h.
The crystals are centrifuged at a speed of 700 revolutions/minute. The
centrifuged crystals of calcium acexamate are washed twice on the centrifuge
with 20 l of acetone. 107.0 kg of crystals are obtained, which are dried under
vacuum at 40°C. The 96.0 kg of dry calcium acexamate obtained are ground
and sifted.
Acexamic acid may be produced by treatment of the calcium acexamate with
HCl.
Therapeutic Function
Antifibrinolytic
6-Acetamidohexanoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-Acetamidohexanoic acid manufacturers
- Product
- 6-Acetamidohexanoic acid 57-08-9
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-11-04
- Product
- 6-Acetamidohexanoic acid 57-08-9
- Price
- US $56.00/g/Bag
- Min. Order
- 5g
- Purity
- 99%
- Supply Ability
- 200KG
- Release date
- 2021-06-07
- Product
- 6-Acetamidohexanoic acid 57-08-9
- Price
- US $8.00/g
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 5ton/Month
- Release date
- 2021-11-26