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6-Acetamidohexanoic acid

Product Name
6-Acetamidohexanoic acid
CAS No.
57-08-9
Chemical Name
6-Acetamidohexanoic acid
Synonyms
AACA;CY 153;AceMin;Plastenan;Acexamic Acid;Acetaminocaproic acid;6-Acetamidocaproic acid;e-Acetamidocaproic Acid;6-acetylaminocaproicacid;6-ACETAMINOHEXANOIC ACID
CBNumber
CB5168240
Molecular Formula
C8H15NO3
Formula Weight
173.21
MOL File
57-08-9.mol
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6-Acetamidohexanoic acid Property

Melting point:
102-104 °C(lit.)
Boiling point:
303.86°C (rough estimate)
Density 
1.1599 (rough estimate)
refractive index 
1.4590 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Sparingly), Methanol (Slightly)
pka
4.75±0.10(Predicted)
form 
Solid
color 
White to Off-White
Merck 
14,45
LogP
-0.500 (est)
CAS DataBase Reference
57-08-9(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29241900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Alfa Aesar
Product number
B23623
Product name
6-Acetamidohexanoic acid hydrate, 99%
Packaging
5g
Price
$25.65
Updated
2024/03/01
Alfa Aesar
Product number
B23623
Product name
6-Acetamidohexanoic acid hydrate, 99%
Packaging
25g
Price
$61.65
Updated
2024/03/01
TRC
Product number
A158410
Product name
6-AcetamidohexanoicAcid
Packaging
2.5g
Price
$65
Updated
2021/12/16
TRC
Product number
A158410
Product name
6-AcetamidohexanoicAcid
Packaging
10g
Price
$110
Updated
2021/12/16
TRC
Product number
A158410
Product name
6-AcetamidohexanoicAcid
Packaging
100g
Price
$340
Updated
2021/12/16
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6-Acetamidohexanoic acid Chemical Properties,Usage,Production

Chemical Properties

WHITE POWDER

Originator

Acexamic acid ,Flamma

Uses

wound healing agent

Uses

6-Acetamidohexanoic acid is used after oral administration of an antiulcer agent, zinc acexamate (ZAC) for treatment of gastric ulcer or small bowel inflammation.

Definition

ChEBI: Acexamic acid is a medium-chain fatty acid.

Manufacturing Process

400 L of demineralized water, 5.0 kg of calcium hydroxide, and 155.0 kg (1000 moles) of acetyl-caprolactame are introduced under stirring and at a temperature of about 25°C into a 1000 L stainless double walled reactor.
The temperature is raised to 30°C. 75.0 kg of calcium hydroxide are introduced stepwise in the form of successive amounts of 2.0 kg each in the medium, under stirring and at a temperature adjusted and maintained 25°- 30°C through external cooling, in a manner such that the time required to introduce into the reactor the whole amount of calcium hydroxide approximates 1.5 h. When the stirring is stopped, the pH is about 7.5-7.8.
The obtained mixture is stirred continuously at a temperature of 30°C during 14 h. At the end of this operation the pH is again adjusted at a value 7.5-7.8.
The hydrolysate is filtered on a 60 x 60 pressfilter comprising 6 compartments and equipped with fabrics of the polyester known under the designation TERGAL which have been previously coated with a suspension of a cellulose commercialized under the trademark SOLKA FLOX BW20. The duration of filtration is of 1.5 h. 580 L of the filtrate are recovered and subjected to a concentration under reduced pressure in an evaporator the volume of which is of 750 L, at a distillation temperature ranging from 45°-50°C under a reduced pressure of 10-15 Torr.
The operation is ran until concentration of the solution to 280 L, the concentrated solution being then left standing. The crystallisation is already considerable 2 h after the end of the operation of concentration. Crystallisation is ended after 16-24 h.
The crystals are centrifuged at a speed of 700 revolutions/minute. The centrifuged crystals of calcium acexamate are washed twice on the centrifuge with 20 l of acetone. 107.0 kg of crystals are obtained, which are dried under vacuum at 40°C. The 96.0 kg of dry calcium acexamate obtained are ground and sifted.
Acexamic acid may be produced by treatment of the calcium acexamate with HCl.

Therapeutic Function

Antifibrinolytic

6-Acetamidohexanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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6-Acetamidohexanoic acid Suppliers

Matrix Fine Chemicals GmbH
Tel
--
Fax
--
Email
nfo@matrix-fine-chemicals.com
Country
Switzerland
ProdList
6968
Advantage
58
SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
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View Lastest Price from 6-Acetamidohexanoic acid manufacturers

hebei hongtan Biotechnology Co., Ltd
Product
6-Acetamidohexanoic acid 57-08-9
Price
US $30.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
2000kg
Release date
2024-03-25
Hebei Weibang Biotechnology Co., Ltd
Product
6-Acetamidohexanoic acid 57-08-9
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-11-04
Hebei Mojin Biotechnology Co., Ltd
Product
6-Acetamidohexanoic acid 57-08-9
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-11-30

57-08-9, 6-Acetamidohexanoic acidRelated Search:


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