2-(Trifluoromethyl)benzoyl chloride

Product Name: 2-(Trifluoromethyl)benzoyl chloride
CAS No.: 312-94-7
Chemical Name: 2-(Trifluoromethyl)benzoyl chloride
Synonyms: alpha,alpha,alpha-Trifluoro-o-toluoyl chloride;à;OTF-BOC;TIMTEC-BB SBB006689;TrifluoroMethyl)benzoyl chlori;α,α,α-trifluoro-o-toluoyl chloride;à,à,à-trifluoro-o-toluoyl chloride;2-(TrifluoroMehtyl)benzoylcholride;2-(TRIFLUOROMETHYL)BENZOYL CHLORIDE;O-(TRIFLUOROMETHYL)BENZOYL CHLORIDE
CBNumber: CB5193552
Molecular Formula: C8H4ClF3O
Formula Weight: 208.57
MOL File: 312-94-7.mol

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2-(Trifluoromethyl)benzoyl chloride Property

Melting point:: -22 °C
Boiling point:: 84-85 °C16 mm Hg(lit.)
Density: 1.416 g/mL at 25 °C(lit.)
vapor pressure: 60.66Pa at 25℃
refractive index: n20/D 1.479(lit.)
Flash point:: 204 °F
storage temp.: Inert atmosphere,Room Temperature
form: Liquid
Specific Gravity: 1.416
color: Clear pink or yellow
Water Solubility: decomposes
Sensitive: Lachrymatory
BRN: 881040
LogP: 2.086
CAS DataBase Reference: 312-94-7(CAS DataBase Reference)
NIST Chemistry Reference: 2-(Trifluoromethyl)benzoyl chloride(312-94-7)

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Safety

Hazard Codes: C
Risk Statements: 34-37-29
Safety Statements: 26-36/37/39-45-8
RIDADR: UN 3265 8/PG 2
WGK Germany: 3
F: 19-21
Hazard Note: Corrosive/Lachrymatory
HazardClass: 8
PackingGroup: II
HS Code: 29163990
Toxicity: skn-rbt 500 mg/24H MOD FCTXAV 13,681,75

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H290May be corrosive to metals

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

Precautionary statements

P234Keep only in original container.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P309IF exposed or if you feel unwell:

P310Immediately call a POISON CENTER or doctor/physician.

P390Absorb spillage to prevent material damage.

P405Store locked up.

P406Store in corrosive resistant/… container with a resistant inner liner.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 249483
Product name: 2-(Trifluoromethyl)benzoyl chloride
Purity: 99%
Packaging: 25g
Price: $271
Updated: 2023/01/07

TCI Chemical

Product number: T1280
Product name: 2-(Trifluoromethyl)benzoyl Chloride
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $36
Updated: 2025/07/31

TRC

Product number: T791135
Product name: 2-(Trifluoromethyl)benzoyl chloride
Packaging: 100g
Price: $495
Updated: 2021/12/16

TRC

Product number: T791135
Product name: 2-(Trifluoromethyl)benzoyl chloride
Packaging: 25g
Price: $165
Updated: 2021/12/16

Apolloscientific

Product number: PC7590
Product name: 2-(Trifluoromethyl)benzoyl chloride
Purity: 98%
Packaging: 500g
Price: $280
Updated: 2021/12/16

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2-(Trifluoromethyl)benzoyl chloride Chemical Properties,Usage,Production

Chemical Properties

colorlesstolightyellowliqui

Uses

2-(Trifluoromethyl)benzoyl chloride may be used in chemical synthesis.

Safety Profile

A skin irritant. When heated todecomposition it emits acrid smoke and irritating fumes.

Synthesis

433-97-6

312-94-7

Step 2: Synthesis of 2-(trifluoromethyl)benzoyl chloride Oxalyl chloride (36.72 mg, 0.29 mmol) was slowly added to a stirred solution of 2-(trifluoromethyl)benzoic acid (50 mg, 0.26 mmol) in dichloromethane (3 mL) followed by dropwise addition of N,N-dimethylformamide (DMF, 4 drops). The resulting reaction mixture was stirred at room temperature for 1 hour. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure and 2-(trifluoromethyl)benzoyl chloride (95.6 mg, 100% yield) was obtained quantitatively, which was used directly in the subsequent reaction without purification.

References

[1] Patent: US2010/160323, 2010, A1. Location in patent: Page/Page column 28
[2] Journal of the American Chemical Society, 1947, vol. 69, p. 2352
[3] Bulletin de la Societe Chimique de France, 1962, p. 587 - 593
[4] Journal of Medicinal Chemistry, 1982, vol. 25, # 2, p. 145 - 152
[5] Journal of Medicinal Chemistry, 1999, vol. 42, # 6, p. 981 - 991

2-(Trifluoromethyl)benzoyl chloride Preparation Products And Raw materials

Raw materials

2-(Trifluoromethyl)benzoic acid

Preparation Products

Flutolanil

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2-(Trifluoromethyl)benzoyl chloride Suppliers

Belgium 2 Canada 1 China 248 Europe 3 France 2 Germany 5 India 8 Italy 1 Japan 9 Slovakia 1 Switzerland 2 Ukraine 2 United Kingdom 20 United States 46 Global 350

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View Lastest Price from 2-(Trifluoromethyl)benzoyl chloride manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 2-(Trifluoromethyl)benzoyl chloride 312-94-7
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-06-24

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 2-(Trifluoromethyl)benzoyl chloride 312-94-7
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-25

Henan Fengda Chemical Co., Ltd

Product: 2-(Trifluoromethyl)benzoyl chloride 312-94-7
Price: US $8.00-0.80/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-01-22

312-94-7, 2-(Trifluoromethyl)benzoyl chlorideRelated Search:

3-(Trifluoromethyl)benzaldehyde Allylbenzene Trifluoromethanesulfonic acid Calcium chloride Polyvinyl chloride 2-Fluorobenzoyl chloride Benzoyl chloride 2-(Trifluoromethyl)benzoic acid 2-(Trifluoromethyl)benzaldehyde 2-Aminobenzotrifluoride 3-Methylbenzoyl chloride 4-(Chloromethyl)benzoyl chloride Choline chloride p-Toluoyl chloride 2-(Trifluoromethyl)benzyl chloride Benzene Benzoyl peroxide 2,4,6-Trimethylbenzoyl chloride

Benzoyl chloride, 2-(trifluoromethyl)-

TIMTEC-BB SBB006689

O-(TRIFLUOROMETHYL)BENZOYL CHLORIDE

OTF-BOC

o-Trifluoromethylbenzoyl Chloride 2-Trifluoromethylbenzoyl Chloride

alpha,alpha,alpha-Trifluoro-o-toluoyl chloride

2-(Trifluoromethyl)benzene-1-carbonyl chloride

2-(TRIFLUOROMETHYL)BENZOYL CHLORIDE

à,à,à-trifluoro-o-toluoyl chloride

α,α,α-trifluoro-o-toluoyl chloride

2-(Trifluoromethyl)benzoyl chloride 98%

2-(Trifluoromethyl)benzoylchloride98%

2-(Trifluoromethyl)benzoic acid chloride

à

O-(triflouromethyl)benzoyl Chloride

2-(Trifluoromethyl)benzoyl chloride,α,α,α-Trifluoro-o-toluoyl chloride

2-(TrifluoroMehtyl)benzoylcholride

2- threefluorine Methylbenzoyl chloride

(2-Chlorocarbonyl)benzotrifluoride, alpha,alpha,alpha-Trifluoro-o-toluoyl chloride

TrifluoroMethyl)benzoyl chlori

2-(Trifluoromethyl)benzoyl chloride,97%

312-94-7

331-94-7

321-97-4

331-94-7

F3CC6H4COCl

C8F3H4OCl

Building Blocks

Carbonyl Compounds

ACID CHLORIDE

Organic Building Blocks

Acid Halides

Aromatic Halides (substituted)

Trifluoromethylbenzene serise