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METHYL BENZO[B]THIOPHENE-2-CARBOXYLATE

Application
Product Name
METHYL BENZO[B]THIOPHENE-2-CARBOXYLATE
CAS No.
22913-24-2
Chemical Name
METHYL BENZO[B]THIOPHENE-2-CARBOXYLATE
Synonyms
AKOS 91623;BUTTPARK 86\18-02;Methyl benzo[b<;RARECHEM AL BF 0483;Thianaphthene-2-carboxylate;Methyl Benzothiophene Carboxylate;METHYL THIANAPHTHENE-2-CARBOXYLATE;Methyl 2-benzothiophenecarboxylate;methyl 1-benzothiophene-2-carboxylate;METHYL BENZO[B]THIOPHENE-2-CARBOXYLATE
CBNumber
CB5203938
Molecular Formula
C10H8O2S
Formula Weight
192.23
MOL File
22913-24-2.mol
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METHYL BENZO[B]THIOPHENE-2-CARBOXYLATE Property

Melting point:
70-74 °C
Boiling point:
304.6±15.0 °C(Predicted)
Density 
1.273±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
form 
solid
Appearance
Light yellow to yellow Solid
BRN 
142166
InChI
InChI=1S/C10H8O2S/c1-12-10(11)9-6-7-4-2-3-5-8(7)13-9/h2-6H,1H3
InChIKey
KRRAZMUPVIGDCU-UHFFFAOYSA-N
SMILES
C12=CC=CC=C1C=C(C(OC)=O)S2
CAS DataBase Reference
22913-24-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26
WGK Germany 
3
HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
666432
Product name
Methyl benzo[b]thiophene-2-carboxylate
Purity
97%
Packaging
10g
Price
$116
Updated
2025/07/31
Sigma-Aldrich
Product number
666432
Product name
Methyl benzo[b]thiophene-2-carboxylate
Purity
97%
Packaging
1g
Price
$48.9
Updated
2023/06/20
TRC
Product number
M650000
Product name
Methyl benzo[b]thiophene-2-carboxylate
Packaging
500mg
Price
$75
Updated
2021/12/16
Apolloscientific
Product number
OR951927
Product name
Methyl benzo[b]thiophene-2-carboxylate
Purity
95%
Packaging
1g
Price
$90
Updated
2021/12/16
Matrix Scientific
Product number
156020
Product name
Methyl 1-benzothiophene-2-carboxylate
Packaging
0.500g
Price
$160
Updated
2021/12/16
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METHYL BENZO[B]THIOPHENE-2-CARBOXYLATE Chemical Properties,Usage,Production

Application

Methylbenzothiophene-2-carboxaldehyde is an organic synthesis intermediate used in laboratory research and development processes and in chemical and pharmaceutical synthesis. It is obtained by esterification of benzothiophene-2-carboxylate. It can be used to synthesize 2-substituted-1,3,4-oxadiazine ones – compound 4.

Synthesis

67-56-1

6314-28-9

22913-24-2

General procedure for the synthesis of methylbenzothiophene-2-carbaldehyde from methanol and benzothiophene-2-carboxylic acid: 2-benzothiophenecarboxylic acid (1.0 g, 5.61 mmol, 1.0 eq.) was dissolved in 20 mL of methanol, followed by the addition of concentrated sulfuric acid (0.1 g) as catalyst. The reaction mixture was stirred at 60 °C for 16 hours. Upon completion of the reaction, 50 mL of saturated aqueous sodium bicarbonate was added to the reaction mixture to neutralize the acidic conditions. Subsequently, the organic phase was separated by extraction with ethyl acetate. The organic phase was sequentially washed with saturated brine and dried over anhydrous sodium sulfate. Finally, the organic phase was concentrated under reduced pressure to afford the target product methyl 2-benzothiophenecarboxylate (1.05 g, 97.4% yield) as a white solid.

References

[1] Synlett, 2004, # 6, p. 1113 - 1116
[2] Patent: CN107383024, 2017, A. Location in patent: Paragraph 0407

METHYL BENZO[B]THIOPHENE-2-CARBOXYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

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METHYL BENZO[B]THIOPHENE-2-CARBOXYLATE Suppliers

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View Lastest Price from METHYL BENZO[B]THIOPHENE-2-CARBOXYLATE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
METHYL BENZO[B]THIOPHENE-2-CARBOXYLATE 22913-24-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
METHYL BENZO[B]THIOPHENE-2-CARBOXYLATE 22913-24-2
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000KGS
Release date
2020-01-08

22913-24-2, METHYL BENZO[B]THIOPHENE-2-CARBOXYLATERelated Search:


  • RARECHEM AL BF 0483
  • BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER
  • BUTTPARK 86\18-02
  • AKOS 91623
  • Benzo[b]thiophene-2-carboxylic acid methyl ester~Methyl thianaphthene-2-carboxylate~Thianaphthene-2-carboxylic acid methyl ester
  • Benzothiophene-2-Carboxylic Acid Methyl Ester
  • Benzo(b)thiophene-2-cyrboxylic acid methylester
  • Benzo[b]thiophene-2-carboxylicacidmethylester~Methylthianaphthene-2-carboxylate~Thianaphthene-2-carboxylicacidmeth
  • Methylbenzo&Auml;b&Uuml;thiophene-2-carboxylate,97%
  • Methyl benzobüthiophene-2-carboxylate, 97%
  • Benzo[b]thiophene-2-carboxylic acid methyl ester, Methyl thianaphthene-2-carboxylate
  • methyl 1-benzothiophene-2-carboxylate
  • Methyl Benzothiophene Carboxylate
  • Thianaphthene-2-carboxylate
  • Thianaphthene-2-carboxylic acid methyl ester
  • METHYL BENZO[B]THIOPHENE-2-CARBOXYLATE
  • METHYL THIANAPHTHENE-2-CARBOXYLATE
  • 2-benzothiophene-1-carboxylic acid methyl ester
  • METHYL BENZO[B]THIOPHENE-2-CARBOXYLATE ISO 9001:2015 REACH
  • Methyl benzo[b]thiophene-2-carboxylate-98%
  • Methyl 2-benzothiophenecarboxylate
  • Methyl benzo[<I>b<
  • Methyl benzo[<i>b</i>]thiophene-2-carboxylate
  • 22913-24-2
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  • Benzothiophenes
  • Heterocyclic Building Blocks