5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzo[d]thiazole

Product Name: 5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzo[d]thiazole
CAS No.: 1073354-91-2
Chemical Name: 5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzo[d]thiazole
Synonyms: 5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzo[d]thiazole
CBNumber: CB82598509
Molecular Formula: C13H16BNO2S
Formula Weight: 261.15
MOL File: 1073354-91-2.mol

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5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzo[d]thiazole Property

Boiling point:: 380.6±15.0 °C(Predicted)
Density: 1.17±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 0.60±0.10(Predicted)
InChI: InChI=1S/C13H16BNO2S/c1-12(2)13(3,4)17-14(16-12)9-5-6-11-10(7-9)15-8-18-11/h5-8H,1-4H3
InChIKey: MGOKEBHEDJCRQN-UHFFFAOYSA-N
SMILES: S1C2=CC=C(B3OC(C)(C)C(C)(C)O3)C=C2N=C1

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Safety

HS Code: 2934208090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: B206843
Product name: Benzothiazole-5-boronicAcidPinacolEster
Packaging: 500mg
Price: $230
Updated: 2021/12/16

TRC

Product number: B206843
Product name: Benzothiazole-5-boronicAcidPinacolEster
Packaging: 1g
Price: $330
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: BOR0003661
Product name: 5-BENZOTHIAZOLE BORONIC ACID PINACOL ESTER
Purity: 95.00%
Packaging: 1G
Price: $340.2
Updated: 2021/12/16

AK Scientific

Product number: Y6969
Product name: 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]thiazole
Packaging: 5g
Price: $382
Updated: 2021/12/16

Matrix Scientific

Product number: 091589
Product name: 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]thiazole
Purity: 95+%
Packaging: 1g
Price: $504
Updated: 2021/12/16

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5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzo[d]thiazole Chemical Properties,Usage,Production

Synthesis

768-11-6

73183-34-3

1073354-91-2

A mixture was prepared from 5-bromobenzo[d]thiazole (428 mg, 2.00 mmol), bis(pinacolato)diboron (558 mg, 2.20 mmol) and potassium acetate (588 mg, 6.00 mmol) in dimethylsulfoxide (7 mL). The mixture was stirred under nitrogen protection for 5 min. Subsequently, [1,1'-bis(diphenylphosphino)ferrocene]palladium(II) dichloride dichloromethane complex (293 mg, 0.40 mmol) was added and the reaction mixture was stirred for 3 hours at 85 °C. Upon completion of the reaction, the mixture was filtered through a diatomaceous earth pad and the filter cake was washed with ethyl acetate (75 mL) followed by water (20 mL). The filtrate was diluted with ethyl acetate (100 mL) and washed sequentially with water (2 x 75 mL) and brine (75 mL). The organic phase was dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The residue was purified by column chromatography (silica gel as stationary phase, eluent was a mixture of dichloromethane and ethyl acetate, gradient elution, volume fraction of ethyl acetate was increased from 0% to 50%) to afford the target product 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]thiazole (200 mg, 38% yield) as a light brown solid. The structure of the product was confirmed by 1H NMR (300 MHz, DMSO-d6) and ESI MS: 1H NMR δ 9.41 (s, 1H), 8.32 (s, 1H), 8.18 (d, 1H, J = 8.0 Hz), 7.72 (d, 1H, J = 8.0 Hz), 1.33 (s, 12H); ESI MS m/z 262.1 [M + H ]+.

References

[1] Patent: WO2010/68257, 2010, A1. Location in patent: Page/Page column 92-93
[2] Patent: WO2009/14637, 2009, A2. Location in patent: Page/Page column 173-174
[3] Patent: WO2011/66211, 2011, A1. Location in patent: Page/Page column 86-87
[4] Patent: CN108707139, 2018, A. Location in patent: Paragraph 0612; 0614; 0655; 0656; 0657; 0658

5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzo[d]thiazole Preparation Products And Raw materials

Raw materials

Preparation Products

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5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzo[d]thiazole Suppliers

China 56 India 1 United States 7 Global 64

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View Lastest Price from 5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzo[d]thiazole manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzo[d]thiazole 1073354-91-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-03-28

Career Henan Chemical Co

Product: 5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzo[d]thiazole 1073354-91-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2020-01-08

1073354-91-2, 5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzo[d]thiazoleRelated Search:

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5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzo[d]thiazole

1073354-91-2