5-(Aminomethyl)-2-chloropyridine
- Product Name
- 5-(Aminomethyl)-2-chloropyridine
- CAS No.
- 97004-04-1
- Chemical Name
- 5-(Aminomethyl)-2-chloropyridine
- Synonyms
- (6-CHLOROPYRIDIN-3-YL)METHANAMINE;C-(6-Chloro-pyridin-3-yl)-methylamine;)-2-chL;Albb-008885;MFCD17976995;RARECHEM AL BW 0722;6-Chloro-3-Picolylamine;5-(Aminomethyl)-2-chlorop...;6-Chloro-3-pyridylmethylamine;6-chloro-3-pyridinemethanamine
- CBNumber
- CB5214246
- Molecular Formula
- C6H7ClN2
- Formula Weight
- 142.59
- MOL File
- 97004-04-1.mol
5-(Aminomethyl)-2-chloropyridine Property
- Melting point:
- 28-34 °C
- Boiling point:
- 101-102°C 1mm
- Density
- 1.244±0.06 g/cm3(Predicted)
- Flash point:
- >230 °F
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- pka
- 7.78±0.29(Predicted)
- form
- Oil to Low-Melting Solid
- color
- Off-White to Light Brown
- Sensitive
- Hygroscopic
- BRN
- 8308740
- Stability:
- Hygroscopic
- InChI
- InChI=1S/C6H7ClN2/c7-6-2-1-5(3-8)4-9-6/h1-2,4H,3,8H2
- InChIKey
- XPARFBOWIYMLMY-UHFFFAOYSA-N
- SMILES
- C1=NC(Cl)=CC=C1CN
- CAS DataBase Reference
- 97004-04-1(CAS DataBase Reference)
Safety
- Hazard Codes
- T,C
- Risk Statements
- 25-37/38-41-43-34
- Safety Statements
- 26-36/37/39-45-20
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- HazardClass
- 8
- PackingGroup
- III
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H317May cause an allergic skin reaction
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 536008
- Product name
- 5-(Aminomethyl)-2-chloropyridine
- Purity
- 97%
- Packaging
- 5g
- Price
- $152
- Updated
- 2025/07/31
- Product number
- 536008
- Product name
- 5-(Aminomethyl)-2-chloropyridine
- Purity
- 97%
- Packaging
- 25g
- Price
- $362.63
- Updated
- 2025/07/31
- Product number
- A2155
- Product name
- 5-(Aminomethyl)-2-chloropyridine
- Purity
- min. 97.0 %
- Packaging
- 1G
- Price
- $93
- Updated
- 2025/07/31
- Product number
- A2155
- Product name
- 5-(Aminomethyl)-2-chloropyridine
- Purity
- min. 97.0 %
- Packaging
- 5G
- Price
- $369
- Updated
- 2025/07/31
- Product number
- A615370
- Product name
- 5-Aminomethyl-2-chloropyridine
- Packaging
- 25g
- Price
- $545
- Updated
- 2021/12/16
5-(Aminomethyl)-2-chloropyridine Chemical Properties,Usage,Production
Chemical Properties
White to Off-white crystal
Uses
5-Aminomethyl-2-chloropyridine is a reagent that is used in the synthesis of macamides and analogs that have FAAH (fatty acid amide hydrolase) inhibitory activity.
Synthesis
1080018-12-7
97004-04-1
General procedure for the synthesis of 5-aminomethyl-2-chloropyridine from the compound (CAS:1080018-12-7) (Example 5): preparation of (2-chloropyridin-5-yl)methylamine (4). To 0.77 g (1.66 mmol) of 1,3,5-tris[(2-chloropyridin-5-yl)methyl]-1,3,5-perhydrotriazine (II-4) were sequentially added 0.40 g of methanol and 1.83 g of concentrated hydrochloric acid, and the resultant mixture was stirred for 6 hr. at 75 to 80° C. The reaction was carried out with the aid of a liquid chromatograph. After completion of the reaction, the reaction mixture was diluted with chloroform and adjusted to basicity by addition of 28% aqueous sodium hydroxide. The chloroform layer was separated and concentrated to give 0.68 g (yield: 95%) of the target product (2-chloropyridin-5-yl)methylamine (III-1).
References
[1] Patent: EP2141149, 2010, A1. Location in patent: Page/Page column 17
[2] Patent: US2010/121054, 2010, A1. Location in patent: Page/Page column 9
5-(Aminomethyl)-2-chloropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-(Aminomethyl)-2-chloropyridine manufacturers
- Product
- 5-(Aminomethyl)-2-chloropyridine 97004-04-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%-100%
- Supply Ability
- 1
- Release date
- 2018-08-10