Ganoderenic acid D
- Product Name
- Ganoderenic acid D
- CAS No.
- 100665-43-8
- Chemical Name
- Ganoderenic acid D
- Synonyms
- Ganoderenic acid d;Apoptosis,Inhibitor,inhibit,Ganoderenic acid D;(20E)-7β-Hydroxy-3,11,15,23-tetraoxolanosta-8,20(22)-diene-26-oic acid;(20E)-7β-Hydroxy-3,11,15,23-tetraoxo-5α-lanosta-8,20(22)-dien-26-oic acid;(7beta,20E)-7-Hydroxy-3,11,15,23-tetraoxolanosta-8,20(22)-dien-26-oic acid;Lanosta-8,20(22)-dien-26-oic acid, 7-hydroxy-3,11,15,23-tetraoxo-, (7β,20E)-;(E)-6-((5R,7S,10S,13R,14R,17R)-7-Hydroxy-4,4,10,13,14-pentamethyl-3,11,15-trioxo-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methyl-4-oxohept-5-enoic acid
- CBNumber
- CB52192797
- Molecular Formula
- C30H40O7
- Formula Weight
- 512.6344
- MOL File
- 100665-43-8.mol
Ganoderenic acid D Property
- Melting point:
- 218-220℃
- Boiling point:
- 702.3±60.0 °C(Predicted)
- Density
- 1.24±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
- pka
- 4.63±0.23(Predicted)
- color
- White to off-white
N-Bromosuccinimide Price
- Product number
- 300301
- Product name
- Ganoderenic acid D
- Packaging
- 10mg
- Price
- $490
- Updated
- 2021/12/16
- Product number
- orb259246
- Product name
- Ganoderenic acid D
- Purity
- 98%
- Packaging
- 5mg
- Price
- $654.5
- Updated
- 2021/12/16
- Product number
- 3481
- Product name
- Ganoderenic acid D
- Packaging
- 10mg
- Price
- $590
- Updated
- 2021/12/16
- Product number
- 3481
- Product name
- Ganoderenic acid D
- Packaging
- 2mg
- Price
- $249
- Updated
- 2021/12/16
- Product number
- CFN90300
- Product name
- GanoderenicacidD
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $476
- Updated
- 2021/12/16
Ganoderenic acid D Chemical Properties,Usage,Production
Uses
Ganoderic acid D, a highly oxygenated tetracyclic triterpenoid, is the major active component of Ganoderma lucidum. Ganoderic acid D upregulates the protein expression of SIRT3 and induces the deacetylated cyclophilin D (CypD) by SIRT3. It inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate production, pyruvate and acetyl-coenzyme production in colon cancer cells. It also induces HeLa human cervical carcinoma apoptosis.
Definition
ChEBI: Ganoderenic acid D is a triterpenoid.
Biological Activity
Ganoderenic acid D is a triterpenoid originally isolated from G. lucidum and has diverse biological activities. It inhibits angiotensin-converting enzyme (ACE; IC50 = 734 μM). Ganoderenic acid D is cytotoxic to HepG2 liver, HeLa cervical, and Caco-2 colon cancer cells (IC50s = 0.14, 0.18, and 0.26 mg/ml, respectively). It inhibits LPS-induced nitric oxide (NO) production in BV-2 microglia (IC50 = 13.77 μM).
Ganoderenic acid D Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Ganoderenic acid D manufacturers
- Product
- Ganoderenic acid D 100665-43-8
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-04-13
- Product
- Ganoderenic acid D 100665-43-8
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1kg , 5kg, 50kg
- Release date
- 2020-01-17