ChemicalBook > CAS DataBase List > 3-Oxoolean-12-en-28-oic acid methyl ester

3-Oxoolean-12-en-28-oic acid methyl ester

Product Name
3-Oxoolean-12-en-28-oic acid methyl ester
CAS No.
1721-58-0
Chemical Name
3-Oxoolean-12-en-28-oic acid methyl ester
Synonyms
Methyl oleanonate;methyl 3-oxooleanolate;3-Oxoolean-12-en-28-oic acid methyl ester;Olean-12-en-28-oic acid, 3-oxo-, methyl ester;agonist,oleanolic acid derivative,PPAR,Methyl oleanonate,Inhibitor,MCF-7,HeLa,inhibit,Peroxisome proliferator-activated receptors,PPARγ,Anticancer effect
CBNumber
CB52247756
Molecular Formula
C31H48O3
Formula Weight
468.71
MOL File
1721-58-0.mol
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3-Oxoolean-12-en-28-oic acid methyl ester Property

Melting point:
184 °C
Boiling point:
523.9±50.0 °C(Predicted)
Density 
1.06±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0134812
Product name
Methyloleanonate
Purity
99.49%
Packaging
1mg
Price
$130
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
SHG0005739
Product name
3-OXO-OLEAN-12-EN-28-OIC ACID METHYL ESTER
Purity
95.00%
Packaging
5MG
Price
$499.35
Updated
2021/12/16
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3-Oxoolean-12-en-28-oic acid methyl ester Chemical Properties,Usage,Production

Uses

Methyl oleanonate is a natural triterpene PPARγ agonist isolated from the species of Pistacia lentiscus var. Chia[1]. Methyl oleanonate is a modified oleanolic acid derivative with anti-cancer effects[2].

IC 50

PPARγ

References

[1] Rasmus K Petersen, et al. Pharmacophore-driven identification of PPARγ agonists from natural sources. J Comput Aided Mol Des. 2011 Feb;25(2):107-16. DOI:10.1007/s10822-010-9398-5
[2] Barbara Bednarczyk-Cwynar, et al. Anticancer effect of A-ring or/and C-ring modified oleanolic acid derivatives on KB, MCF-7 and HeLa cell lines. Org Biomol Chem. 2012 Mar 21;10(11):2201-5 DOI:10.1039/c2ob06923g

3-Oxoolean-12-en-28-oic acid methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Oxoolean-12-en-28-oic acid methyl ester Suppliers

J & K SCIENTIFIC LTD.
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