Derrone

Product Name: Derrone
CAS No.: 76166-59-1
Chemical Name: Derrone
Synonyms: Derrone;5-Hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-4H,8H-pyrano[2,3-f]chromen-4-one;5-Hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-4H,8H-benzo[1,2-b:3,4-b']dipyran-4-one;3-(4-Hydroxyphenyl)-5-hydroxy-8,8-dimethyl-4H,8H-benzo[1,2-b:3,4-b']dipyran-4-one;4H,8H-Benzo[1,2-b:3,4-b']dipyran-4-one, 5-hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-
CBNumber: CB52268663
Molecular Formula: C20H16O5
Formula Weight: 336.34
MOL File: 76166-59-1.mol

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Derrone Property

Boiling point:: 584.1±50.0 °C(Predicted)
Density: 1.368±0.06 g/cm3(Predicted)
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: powder
pka: 6.47±0.40(Predicted)
color: Yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Arctom

Product number: AS019084
Product name: Derrone
Packaging: 5mg
Price: $339
Updated: 2021/12/16

CSNpharm

Product number: CSN14824
Product name: Derrone
Packaging: 1mg
Price: $413
Updated: 2021/12/16

Arctom

Product number: CFN97689
Product name: Derrone
Purity: ≥98%
Packaging: 5mg
Price: $553
Updated: 2021/12/16

Crysdot

Product number: CD32000471
Product name: Derrone
Purity: 95+%
Packaging: 5mg
Price: $852
Updated: 2021/12/16

CSNpharm

Product number: CSN14824
Product name: Derrone
Packaging: 5mg
Price: $1033
Updated: 2021/12/16

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Derrone Chemical Properties,Usage,Production

Uses

Derrone, a prenylated isoflavones, is an Aurora kinase inhibitor, with IC50 values of 6 and 22.3 μM against Aurora B and Aurora A, respectively. Derrone shows anti-tumor activity[1][2].

target

Antifection

References

[1] Hoang NT, et al. In Vitro Characterization of Derrone as an Aurora Kinase Inhibitor. Biol Pharm Bull. 2016 Jun 1;39(6):935-45. DOI:10.1248/bpb.b15-00835
[2] Kang MJ, et al. Derrone induces autophagic cell death through induction of ROS and ERK in A549 cells. PLoS One. 2019 Jun 19;14(6):e0218659. DOI:10.1371/journal.pone.0218659

Derrone Preparation Products And Raw materials

Raw materials

Preparation Products

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Derrone Suppliers

China 36 United States 4 Global 40

Chembest Research Laboratories Limited

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BioBioPha Co., Ltd.

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Wuxi Zhongkun Biochemical Technology Co., Ltd.

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ALB Technology Limited

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Wuhan ChemFaces Biochemical Co., Ltd.

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EMMX Biotechnology LLC

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Shanghai YuanYe Biotechnology Co., Ltd.

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Nanjing Digger Medical Technology Co. Ltd.

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Labnetwork lnc.

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Hubei xin bonus chemical co. LTD

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76166-59-1, DerroneRelated Search:

MOSLOFLAVONE alpha-Cyperone Artemether 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one alpha-Terpineol (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one hydroxygenkwanin beta-Eudesmol beta-Sitosterol Hydroxyecdysone

3-(4-Hydroxyphenyl)-5-hydroxy-8,8-dimethyl-4H,8H-benzo[1,2-b:3,4-b']dipyran-4-one

Derrone

5-Hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-4H,8H-benzo[1,2-b:3,4-b']dipyran-4-one

4H,8H-Benzo[1,2-b:3,4-b']dipyran-4-one, 5-hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-

5-Hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-4H,8H-pyrano[2,3-f]chromen-4-one

76166-59-1