Gemifioxacin mesylate
- Product Name
- Gemifioxacin mesylate
- CAS No.
- 210353-53-0
- Chemical Name
- Gemifioxacin mesylate
- Synonyms
- CS-775;LB-20304a;SB-265805S;LB-20304 Mesilate;GEMIFIOXACIN MESYLATE;(Z)-Gemifloxacin Mesilate;Gemifioxacin mesylate, 98.5%;Gemifloxacin Mesylate (300 mg);Gemifioxacin mesylate USP/EP/BP;Gemifloxacin,Inhibitor,inhibit,Gemifloxacin mesylate,Bacterial
- CBNumber
- CB5245303
- Molecular Formula
- C19H24FN5O7S
- Formula Weight
- 485.49
- MOL File
- 210353-53-0.mol
Gemifioxacin mesylate Property
- Melting point:
- 235-2370C
- storage temp.
- room temp
- solubility
- DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly)
- form
- powder
- color
- white to light brown
- Stability:
- Hygroscopic
- CAS DataBase Reference
- 210353-53-0(CAS DataBase Reference)
Safety
- Safety Statements
- 24/25
- HS Code
- 29339900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H341Suspected of causing genetic defects
H373May cause damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P202Do not handle until all safety precautions have been read and understood.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313IF exposed or concerned: Get medical advice/attention.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- SML1625
- Product name
- Gemifloxacin mesylate
- Purity
- ≥98% (HPLC)
- Packaging
- 5MG
- Price
- $105
- Updated
- 2023/06/20
- Product number
- SML1625
- Product name
- Gemifloxacin mesylate
- Purity
- ≥98% (HPLC)
- Packaging
- 25MG
- Price
- $424
- Updated
- 2023/06/20
- Product number
- 21047
- Product name
- Gemifloxacin (mesylate)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $37
- Updated
- 2024/03/01
- Product number
- 21047
- Product name
- Gemifloxacin (mesylate)
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $62
- Updated
- 2024/03/01
- Product number
- 21047
- Product name
- Gemifloxacin (mesylate)
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $119
- Updated
- 2024/03/01
Gemifioxacin mesylate Chemical Properties,Usage,Production
Description
Gemifloxacin is a new fluoroquinolone derivative that is active against both Grampositive and Gram-negative bacteria, and it was launched as an oral treatment for bacterial respiratory infections. Compared with other fluoroquinolones currently on the market, gemifloxacin possesses enhanced in vitro activity against Streptococcus pneumoniae, including isolates resistant to b-lactams, macrolides, and ciprofloxacin. Gemifloxacin is specifically indicated for treating community- acquired pneumonia (CAP) caused by multi-drug resistant S. pneumoniae and for treating acute bacterial exacerbations of chronic bronchitis (AECB). The recommended dose of gemifloxacin is 320 mg daily for 5 days for AECB and 320 mg daily for 7 days for CAP.
Chemical Properties
gemifloxacin mesylate is a synthetic broad-spectrum antibacterial agent for oral administration. Gemifloxacin, a compound related to the fluoroquinolone class of antibiotics, is available as the mesylate salt in the sesquihydrate form. The mesylate salt is a white to light brown solid with a molecular weight of 485.49. Gemifloxacin is considered freely soluble at neutral pH (350 μg/mL at 37oC, pH 7.0).
Originator
LG Life Sciences (S. Korea)
Uses
Third generation fluorinated quinolone antibacterial.
Definition
ChEBI: Gemifloxacin mesylate is the mesylate salt of gemifloxacin. It has a role as an antimicrobial agent and a topoisomerase IV inhibitor. It contains a gemifloxacin.
brand name
Factive
Biochem/physiol Actions
Gemifloxacin is a broad-spectrum quinolone antibacterial. Fluoroquinolones stabilize DNA strand breaks created by DNA gyrase and topoisomerase IV by binding to the enzyme-DNA complex generating persistent, covalent enzyme–DNA adducts, inhibiting DNA synthesis. Gemifloxacin is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. Gemifloxacin has also been found to inhibit migration and invasion of human colon cancer cells.
Gemifioxacin mesylate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Gemifioxacin mesylate manufacturers
- Product
- Gemifioxacin mesylate 210353-53-0
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2021-11-01
- Product
- Gemifioxacin mesylate 210353-53-0
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-08-18
- Product
- Gemifioxacin mesylate 210353-53-0
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons min
- Release date
- 2021-07-19