PYRAZOLO[1,5-A]PYRIMIDINE
- Product Name
- PYRAZOLO[1,5-A]PYRIMIDINE
- CAS No.
- 274-71-5
- Chemical Name
- PYRAZOLO[1,5-A]PYRIMIDINE
- Synonyms
- pyrazolo[2,3-a]pyrimidine;PYRAZOLO[1,5-A]PYRIMIDINE;Pyrazolo[1,5-a]pyrimidine (8CI, 9CI, ACI)
- CBNumber
- CB52454983
- Molecular Formula
- C6H5N3
- Formula Weight
- 119.12
- MOL File
- 274-71-5.mol
PYRAZOLO[1,5-A]PYRIMIDINE Property
- Melting point:
- 105 °C
- Density
- 1.29±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 0.33±0.30(Predicted)
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P846520
- Product name
- Pyrazolo[1,5-a]pyrimidine
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- CHM0096801
- Product name
- PYRAZOLO[1,5-A]PYRIMIDINE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $1024.78
- Updated
- 2021/12/16
- Product number
- X7988
- Product name
- Pyrazolo[1,5-a]pyrimidine
- Packaging
- 5g
- Price
- $351
- Updated
- 2021/12/16
- Product number
- OR301222
- Product name
- Pyrazolo[1,5-a]pyrimidine
- Purity
- 98%
- Packaging
- 1g
- Price
- $95
- Updated
- 2021/12/16
- Product number
- 3H32-1-32
- Product name
- Pyrazolo[1,5-a]pyrimidine
- Purity
- 96%
- Packaging
- 1g
- Price
- $104
- Updated
- 2021/12/16
PYRAZOLO[1,5-A]PYRIMIDINE Chemical Properties,Usage,Production
Chemical Properties
Light yellow solid
Uses
Pyrazolo[1,5-a]pyrimidine is being researched as a protein kinase CK2 inhibitors.
Synthesis
1820-80-0
927-63-9
274-71-5
Preparation of compound 23a: 1H-pyrazol-3-ylamine (32 g, 0.386 mol) and (E)-3-dimethylaminoacrylaldehyde (38.2 g, 0.386 mol) were dissolved in ethanol (500 mL), and the reaction was carried out at reflux for 6 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure and the resulting residue was purified by column chromatography (eluent: petroleum ether/ethyl acetate = 10:1 to 2:1) to afford the target product, pyrazolo[1,5-a]pyrimidine 23a, as a white solid (30 g, 65% yield).
References
[1] Synthesis, 2006, # 1, p. 59 - 62
[2] Patent: WO2010/16005, 2010, A1. Location in patent: Page/Page column 116
PYRAZOLO[1,5-A]PYRIMIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
PYRAZOLO[1,5-A]PYRIMIDINE Suppliers
- Tel
- --
- Fax
- --
- sales@apolloscientific.co.uk
- Country
- United Kingdom
- ProdList
- 6084
- Advantage
- 88
View Lastest Price from PYRAZOLO[1,5-A]PYRIMIDINE manufacturers
- Product
- PYRAZOLO[1,5-A]PYRIMIDINE 274-71-5
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2018-12-24