ChemicalBook > CAS DataBase List > 3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester

3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester

Product Name
3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester
CAS No.
35286-58-9
Chemical Name
3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester
Synonyms
Gouguside 7;Kudinoside H;Zigu-glucoside I;Ziyu-glycoside Ⅰ;Ulmus pumila saponin I;3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester;Urs-12-en-28-oic acid, 3-(α-L-arabinopyranosyloxy)-19-hydroxy-, β-D-glucopyranosyl ester, (3β)-;3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester(Kudinoside H:Ziyuglycoside I);[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1R,2R,4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-1-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-10-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxy-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate
CBNumber
CB52462159
Molecular Formula
C41H66O13
Formula Weight
766.95
MOL File
35286-58-9.mol
More
Less

3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester Property

Melting point:
198-202 ºC
Boiling point:
841.9±65.0 °C(Predicted)
Density 
1.35
storage temp. 
-20°C, protect from light
solubility 
Soluble in acetonitrile and methanol;
form 
powder
pka
12.52±0.70(Predicted)
color 
White
Water Solubility 
insoluble in water
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL84269
Product name
Ziyuglycoside I
Purity
phyproof? Reference Substance
Packaging
10MG
Price
$435
Updated
2023/06/20
Biosynth Carbosynth
Product number
MZ44395
Product name
Ziyuglycoside I
Packaging
50mg
Price
$470
Updated
2021/12/16
Biorbyt Ltd
Product number
orb573030
Product name
3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester
Purity
>98%,Standard References Grade
Packaging
1g
Price
$3432.3
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
107509
Product name
ZiyuglycosideI
Packaging
10mg
Price
$556
Updated
2021/12/16
ChemScene
Product number
CS-0008893
Product name
ZiyuglycosideI
Purity
98.51%
Packaging
5mg
Price
$50
Updated
2021/12/16
More
Less

3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester Chemical Properties,Usage,Production

Chemical Properties

White crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Burnet.

Uses

Used for content determination/identification/pharmacological experiments, etc.

Biological Activity

Ziyuglycoside I, isolated from the roots of S. officinalis, has anti-wrinkle activity and increases collagen type I expression. It can be used as an active ingredient in cosmetics and induces p53-mediated cell cycle arrest and apoptosis (apoptosis), which can be used in the study of triple-negative breast cancer.

Physiological effects

Ziyuglycoside I has the functions of vasoconstriction, hemostasis and antifungal.

in vitro

Ziyuglycoside I (5-160 μM; 24 hours) reveals a marked anti-proliferation activity with an IC 50 value of 13.96 μM in MDA-MB-231 cells. Ziyuglycoside I ( 5-20 μM; 24 hours) induces MDA-MB-231 cell apoptosis by increasing the percentage of apoptotic cells from 2.43% to 44.76% at 20 μM. Ziyuglycoside I (5-20 μM; 24 hours) induces the cleavage of caspas- 8, caspase-9, and caspase-3, up-regulates the pro-apoptotic protein Bax, and down-regulates anti-apoptotic protein Bal-2, dose-dependently reduces the level of mito-cyto c expression.

Cell Viability Assay

Cell Line: MDA-MB-231 cells < /td>
Concentration: 5 μM, 10 μM, 20 μM, 40 μM, 80 μM, and 160 μM
Incubation Time: 24 hours
Result: Showed cytotoxicity on MDA-MB-231 cells.

Cell Cycle Analysis

Cell Line: MDA-MB-231 cells
Concentration: 5 μM, 10 μM, and 20 μM
Incubation Time: 24 hours
Result: Induced G2/M phase arrest and apoptosis on MDA-MB-231 Cells

Western Blot Analysis

Cell Line: MDA-MB-231 cells
Concentration: 5 μM, 10 μM, and 20 μM
Incubation Time: 24 hours
Result: Induced apoptosis in MDA-MB-231 Cells through Intrinsic and Extrinsic Pathways.

3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester Suppliers

China 127 United Kingdom 1 United States 11 Global 139
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6009
Advantage
61
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11726
Advantage
57
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4667
Advantage
58
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5654
Advantage
65
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4941
Advantage
60
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9725
Advantage
55
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
Advantage
60
Tel
028-83311324 1278112614
Fax
028-83311324
Email
climaxbiotech@gmail.com
Country
China
ProdList
925
Advantage
58
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12338
Advantage
58
Tel
+86-21-65211385-8001 36031160
Fax
+86-21-65211385-8004
Email
sales@shruji.com
Country
China
ProdList
3224
Advantage
55
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
Country
China
ProdList
3989
Advantage
66
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7854
Advantage
58
Tel
028-82610909 13388174823
Fax
8171-1798
Email
scglp@glp-china.com
Country
China
ProdList
1064
Advantage
58
Tel
18981954830
Fax
086-28-85377358
Email
2355253622@qq.com
Country
China
ProdList
1104
Advantage
58
Tel
021-61119791,13386096464
Fax
021-50190009
Email
bzswkf@foxmail.com
Country
China
ProdList
3924
Advantage
50
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9986
Advantage
55
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15185
Advantage
58
Tel
021-61317773
Fax
021-61486878
Email
sales@aspirebio.com
Country
China
ProdList
2881
Advantage
58
Tel
86-021-61559134 15921386130
Fax
021-55068248
Email
3423497944@qq.com
Country
China
ProdList
8147
Advantage
55
Tel
025-58849295 18951903616;
Fax
025-68650336
Email
info@adooq.cn
Country
China
ProdList
2989
Advantage
60
Tel
18607101326 15172504745
Fax
+86-27-84254680
Email
aileen@chemfaces.com
Country
China
ProdList
7059
Advantage
55
Tel
021-61847300 13341622919
Fax
021-61847300
Email
shcss01@163.com
Country
China
ProdList
4809
Advantage
58
Tel
13391486464
Fax
QQ:14748090
Email
samwjf@163.com
Country
China
ProdList
3090
Advantage
55
Tel
010-50973130 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29795
Advantage
68
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12308
Advantage
58
Tel
17721395025
Fax
021-68882955
Email
2423903095@qq.com
Country
China
ProdList
3180
Advantage
58
Tel
021-36031160 13311776681
Email
3338195766@QQ.com
Country
China
ProdList
5175
Advantage
55
Tel
021-69955236-807 13918189704
Fax
021-65211385
Email
chinaruji@chinaruji.com
Country
China
ProdList
5176
Advantage
55
Tel
028-85370565-229 18080489829
Email
3004654993@qq.com
Country
China
ProdList
9218
Advantage
60
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28820
Advantage
58
Tel
028-85142057, 18030712385
Fax
028-85142057 QQ:3591697873
Email
sales@alfabiotech.com
Country
China
ProdList
1925
Advantage
58
Tel
021-021-57127007-6622-6622 15618937986
Fax
+86 (21) 5132-0077
Email
zhaok@nature-standard.com
Country
China
ProdList
3928
Advantage
58
Tel
86-21-50801717-301
Fax
86-21-50800509
Email
wangjh@sirc-tcm.sh.cn
Country
China
ProdList
2070
Advantage
58
Tel
400-400-1332688 18019345275
Fax
400-133-2688
Email
amy@rhawn.cn
Country
China
ProdList
15503
Advantage
58
Tel
17753923223
Fax
0539-6222546
Email
2805221329@qq.com
Country
China
ProdList
1474
Advantage
58
Tel
400-400-400-9004166 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52712
Advantage
58
Tel
15971444841
Fax
18327183813
Email
amber@biochempartner.com
Country
China
ProdList
3063
Advantage
58
Tel
025-025-51191215 18013836722
Fax
025-51191215
Email
2399235533@qq.com
Country
China
ProdList
4933
Advantage
58
Tel
13739298932
Email
531626407@qq.com
Country
China
ProdList
3008
Advantage
58
Tel
+86-400-002-6226 13028896684
Email
sales@rrkchem.com
Country
China
ProdList
56056
Advantage
58
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9730
Advantage
58
Tel
15805159960
Email
1211550495@qq.com
Country
China
ProdList
1795
Advantage
58
Tel
028-87075086 18030859262
Email
2851503756@qq.com
Country
China
ProdList
1922
Advantage
58
Tel
025-+86-02585846866 +86-18094231287
Fax
025-83144123
Email
eric@dasfbio.com
Country
China
ProdList
1987
Advantage
58
Tel
0551-65418671
Fax
0551-65418697
Email
sales@tnjchem.com
Country
China
ProdList
34571
Advantage
58
Tel
+86-27-50766799 +8618062016861
Email
contact@labnetwork.com
Country
China
ProdList
19994
Advantage
58
Tel
+8613367258412
Fax
18062427325
Email
ada@ipurechemical.com
Country
China
ProdList
10326
Advantage
58
Tel
86 18062405514 18062405514
Email
ada@ipurechemical.com
Country
CHINA
ProdList
3465
Advantage
58
Tel
028-85159085
Fax
86-28-85159085 Ex:604
Email
info@aktinchem.com
Country
CHINA
ProdList
1025
Advantage
58
Tel
+86-27-8439 4403 18971486879
Fax
+86-27-8439 4403
Email
sales@chemnorm.com
Country
CHINA
ProdList
2935
Advantage
58
More
Less

View Lastest Price from 3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester manufacturers

Changsha Staherb Natural Ingredients Co., Ltd.
Product
ziyu-glycoside I; 3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester 35286-58-9
Price
US $0.00/KG
Min. Order
1KG
Purity
60%-98% HPLC
Supply Ability
1000KG
Release date
2022-09-16
Shanghai Standard Technology Co., Ltd.
Product
Ziyuglycoside I 35286-58-9
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-11-20

35286-58-9, 3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl esterRelated Search:

Stearic acid Ziyuglycoside II roburic acid Carboxyatractyloside Pachymic acid Madecassoside ALLEOSIDE A Poricoic acid A(F) Madecassic acid dipotassium dihydrogen 15alpha-hydroxy-2beta-[[2-O-isovaleryl-3,4-di-O-sulphonato-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioate Terrestrosin K Terrestrosin D IMIPRAMINE Boron triiodide Garden Burnet Root SOPHORAE FLAVESCENTIS RADIX Itd

  • Ulmus pumila saponin I
  • 3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester
  • Kudinoside H
  • Zigu-glucoside I
  • Gouguside 7
  • Ziyu-glycoside Ⅰ
  • Urs-12-en-28-oic acid, 3-(α-L-arabinopyranosyloxy)-19-hydroxy-, β-D-glucopyranosyl ester, (3β)-
  • [(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1R,2R,4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-1-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-10-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxy-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate
  • 3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester(Kudinoside H:Ziyuglycoside I)
  • 35286-58-9
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract