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Prasugrel Hydrochloride

Product Name
Prasugrel Hydrochloride
CAS No.
389574-19-0
Chemical Name
Prasugrel Hydrochloride
Synonyms
Prasugrel HCl;Prasugrenhydrochloride;2-[2-(Acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)ethanone hydrochloride;Ridomil 72WP;Prasugrel HCI;Unii-G89jq59I13;Effient Hydrochloride;Prasugrel hydrochloric;PRASUGREL HYDROCHLORIDE;LY 640315 Hydrochloride
CBNumber
CB52465251
Molecular Formula
C20H20FNO3S.ClH
Formula Weight
409.907
MOL File
389574-19-0.mol
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Prasugrel Hydrochloride Property

Melting point:
>173?C (dec.)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly)
form 
Solid
color 
White to Pale Brown
InChI
InChI=1S/C20H20FNO3S.ClH/c1-12(23)25-18-10-14-11-22(9-8-17(14)26-18)19(20(24)13-6-7-13)15-4-2-3-5-16(15)21;/h2-5,10,13,19H,6-9,11H2,1H3;1H
InChIKey
JALHGCPDPSNJNY-UHFFFAOYSA-N
SMILES
N1(CCC2SC(OC(C)=O)=CC=2C1)C(C1C=CC=CC=1F)C(=O)C1CC1.Cl
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Safety

HS Code 
2934990002
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
1554104
Product name
Prasugrel Hydrochloride
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
150MG
Price
$715
Updated
2024/03/01
Usbiological
Product number
P5620
Product name
Prasugrel Hydrochloride
Packaging
100mg
Price
$262
Updated
2021/12/16
TRC
Product number
P701150
Product name
PrasugrelHydrochloride
Packaging
1g
Price
$690
Updated
2021/12/16
TRC
Product number
P701150
Product name
PrasugrelHydrochloride
Packaging
10mg
Price
$60
Updated
2021/12/16
TRC
Product number
P701150
Product name
PrasugrelHydrochloride
Packaging
50mg
Price
$150
Updated
2021/12/16
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Prasugrel Hydrochloride Chemical Properties,Usage,Production

Description

Prasugrel hydrochloride (PCR 4099 hydrochloride), a thienopyridine and proagent, inhibits platelet function. Prasugrel hydrochloride is an orally active and potent P2Y12 receptor antagonist and inhibits ADP-induced platelet aggregation.

Chemical Properties

White to Off-White Solid

Uses

A novel antiplatelet agent; it is a third-generation thienopyridine. Antiplatelet agent Prasugrel showed greater platelet inhibition and decreased incidence of ischemic events than Clopidogrel but may induce increased incidence of bleeding in patient with acute coronary syndrome

in vivo

In rat platelets, Prasugrel hydrochloride active metabolite inhibits in vitro platelet aggregation induced by adenosine ADP (10μM) with an IC50 value of 1.8 μM. Prasugrel hydrochloride acts faster and is significantly more potent than Clopidogrel in vivo. Prasugrel hydrochloride is an inactive prodrug that requires metabolic processing in vivo to generate the active antiplatelet metabolite. Prasugrel hydrochloride is rapidly absorbed from the gut. After oral administration of standard-loading doses of 60 mg, maximum plasma levels of the active metabolite are achieved within 1 h, effective, maximum inhibition of platelet aggregation at 1-2 h.

Prasugrel Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Prasugrel Hydrochloride Suppliers

TEVA PHARMACEUTICAL INDUSTRIES LTD
Tel
--
Fax
--
Email
megan.carroll@tevapharm.com
Country
Israel
ProdList
296
Advantage
58
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View Lastest Price from Prasugrel Hydrochloride manufacturers

BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
Product
Prasugrel Hydrochloride 389574-19-0
Price
US $0.00/g
Min. Order
1g
Purity
More Than 99%
Supply Ability
100kg/Month
Release date
2024-09-25
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Prasugrel hydrochloride 389574-19-0
Price
US $0.00/g
Min. Order
50g
Purity
98%min
Supply Ability
10kg
Release date
2022-12-29
Hebei Weibang Biotechnology Co., Ltd
Product
PRASUGREL HYDROCHLORIDE 389574-19-0
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-06

389574-19-0, Prasugrel HydrochlorideRelated Search:


  • PRASUGREL HYDROCHLORIDE
  • 2-[2-(Acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)ethanone hydrochloride
  • Unii-G89jq59I13
  • Prasugrenhydrochloride
  • Prasugrel HCl
  • 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-2H,4H,5H,6H,7H,7aH-thieno[3,2-c]pyridin-2-one
  • acetic acid [5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-2-yl] ester
  • Prasugrel (Discontinued)
  • Ethanone,2-[2-(acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)-,hydrochloride (1:1)
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  • [5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-2-yl] acetate,hydrochloride
  • Effient Hydrochloride
  • LY 640315 Hydrochloride
  • PCR 4099 (hydrochloride)
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  • Prasugrel Hydrochloride (PCR 4099
  • Prasugrel HydrochlorideQ: What is Prasugrel Hydrochloride Q: What is the CAS Number of Prasugrel Hydrochloride Q: What are the applications of Prasugrel Hydrochloride
  • TIANFU-CHEM--PRASUGREL HYDROCHLORIDE
  • Ridomil 72WP
  • Prasugrel Hydrochloride 5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4,5,6,7- tetrahydrothieno[3,2-c]pyridin-2-yl acetate hydrochloride
  • Prasugrel HCI
  • 389574-19-0
  • 89574-19-0
  • C20H20FNO3SHCl
  • C20H20FNO3SClH
  • API