BOC-CYS(TRT)-OSU

Product Name: BOC-CYS(TRT)-OSU
CAS No.: 75179-29-2
Chemical Name: BOC-CYS(TRT)-OSU
Synonyms: BOC-CYS(TRT)-OSU;Boc-L-Cys(Trt)-OSu;(Tert-Butoxy)Carbonyl Cys(Trt)-OSu;BOC-S-TRITYL-L-CYSTEINE N-HYDROXYSUCCINIMIDE ESTER;N-tert-Butoxycarbonyl-S-cysteine N-hydroxysuccinimide ester;N-alpha-t-Butyloxycarbonyl-S-trityl-L-cysteine succinimidyl ester;L-Cysteine, N-[(1,1-dimethylethoxy)carbonyl]-S-(triphenylmethyl)-, 2,5-dioxo-1-pyrrolidinyl ester;2,5-dioxopyrrolidin-1-yl (2R)-2-{[(tert-butoxy)carbonyl]amino}-3-[(triphenylmethyl)sulfanyl]propanoate
CBNumber: CB5248021
Molecular Formula: C31H32N2O6S
Formula Weight: 560.66
MOL File: 75179-29-2.mol

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BOC-CYS(TRT)-OSU Property

Density: 1.30±0.1 g/cm3(Predicted)
storage temp.: Inert atmosphere,2-8°C
pka: 10.57±0.46(Predicted)
Appearance: White to off-white Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Activate Scientific

Product number: AS112982
Product name: Boc-Cys(Trt)-OSu
Purity: 96%
Packaging: 1g
Price: $32
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB166897
Product name: Boc-cys(trt)-osu
Packaging: 5G
Price: $60
Updated: 2021/12/16

AK Scientific

Product number: 1301CV
Product name: Boc-cys(trt)-osu
Packaging: 1g
Price: $80
Updated: 2021/12/16

Activate Scientific

Product number: AS112982
Product name: Boc-Cys(Trt)-OSu
Purity: 96%
Packaging: 5G
Price: $88
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB166897
Product name: Boc-cys(trt)-osu
Packaging: 10g
Price: $100
Updated: 2021/12/16

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BOC-CYS(TRT)-OSU Chemical Properties,Usage,Production

Synthesis

6066-82-6

21947-98-8

87242-61-3

General procedure for the synthesis of the compound (CAS: 87242-61-3) from N-hydroxybutanediimide (NHS) and N-tert-butoxycarbonyl-S-trityl-L-cysteine: under argon protection, N-tert-butoxycarbonyl-S-trityl-L-cysteine (4 g, 10 mmol) and NHS (2.25 g, 19.5 mmol) were dissolved in acetonitrile (40 mL) and cooled to 0°C. Subsequently, N,N'-dicyclohexylcarbodiimide (DCC, 4 g, 19.5 mmol) was added to the solution and the reaction mixture was stirred at 0 °C for 2 hours. After that, the reaction mixture was gradually warmed up to room temperature and stirring was continued for 12 hours. Upon completion of the reaction, the resulting dicyclohexylurea (DCU) was removed by filtration and the filtrate was concentrated under vacuum to remove the solvent. The obtained residue was dissolved in ether and filtered again to remove insoluble matter. Finally, the filtrate was concentrated to give the target compound (5 g, 90% yield) as a yellow to light colored foam. The product was characterized by 1H NMR (CDCl3) and MALDI-TOF MS: 1H NMR (CDCl3) δ 1.43 (s, 9H, 3 × CH3), 2.65-2.82 (m, 6H, 3 × CH2), 4.25-4.38 (m, 1H, CH), 5.83 (br s, 1H, NH), 7.15-7.46 ( m, 15H, triphenylmethyl-H); MALDI-TOF MS: m/z 561.8 [M+H]+, calculated molecular weight of C31H32N2O6S is 560.66.

References

[1] ChemistryOpen, 2018, vol. 7, # 3, p. 256 - 261
[2] European Journal of Medicinal Chemistry, 2012, vol. 50, p. 383 - 392
[3] Organic and Biomolecular Chemistry, 2011, vol. 9, # 3, p. 820 - 833
[4] Organic and Biomolecular Chemistry, 2018, vol. 16, # 28, p. 5102 - 5106

BOC-CYS(TRT)-OSU Preparation Products And Raw materials

Raw materials

Preparation Products

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BOC-CYS(TRT)-OSU Suppliers

China 41 Germany 1 India 1 United Kingdom 1 United States 4 Global 48

NINGBO INNO PHARMCHEM CO.,LTD.

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75179-29-2, BOC-CYS(TRT)-OSURelated Search:

(S)-1-Phenylethanethiol Boc-S-Benzyl-L-cysteine S-Trityl-L-cysteine BOC-CYS(BZL)-OL Boc-S-benzyl-L-cysteine N-hydroxysuccinimide ester BOC-CYS(ET)-OH ALPHA,ALPHA-DIMETHYLBENZYL MERCAPTAN BOC-CYS(ME)-OH N-Boc-S-Trityl-L-cysteine S-TRITYL-3-MERCAPTOPROPIONIC ACID Triphenylmethanethiol L-Cysteine H-CYS(DPM)-OH L-S-T-BUTYLCYSTEINE BOC-CYS(DPM)-OH BOC-CYS(TRT)-OSU H-D-CYS(BZL)-OH BOC-CYS(TBU)-OH

N-tert-Butoxycarbonyl-S-cysteine N-hydroxysuccinimide ester

Boc-L-Cys(Trt)-OSu

N-alpha-t-Butyloxycarbonyl-S-trityl-L-cysteine succinimidyl ester

BOC-S-TRITYL-L-CYSTEINE N-HYDROXYSUCCINIMIDE ESTER

BOC-CYS(TRT)-OSU

(Tert-Butoxy)Carbonyl Cys(Trt)-OSu

2,5-dioxopyrrolidin-1-yl (2R)-2-{[(tert-butoxy)carbonyl]amino}-3-[(triphenylmethyl)sulfanyl]propanoate

L-Cysteine, N-[(1,1-dimethylethoxy)carbonyl]-S-(triphenylmethyl)-, 2,5-dioxo-1-pyrrolidinyl ester

75179-29-2

75197-29-2

C31H32N2O6S

Amino Acids