S-TRITYL-3-MERCAPTOPROPIONIC ACID

Product Name: S-TRITYL-3-MERCAPTOPROPIONIC ACID
CAS No.: 27144-18-9
Chemical Name: S-TRITYL-3-MERCAPTOPROPIONIC ACID
Synonyms: Mpa(Trt);Mpa(Trt)-OH;Mpr(trt);MPR(TRT)-OH;3-(Tritylthio)propanoic acid;3-(Tritylthio)propionic acid;3-MPA(Trt);3-TRITYLMERCAPTO PROPIONIC ACID;Nsc96707;Trt-Mpa-OH
CBNumber: CB4192048
Molecular Formula: C22H20O2S
Formula Weight: 348.46
MOL File: 27144-18-9.mol

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S-TRITYL-3-MERCAPTOPROPIONIC ACID Property

Melting point:: 211-213°C
Boiling point:: 503.8±38.0 °C(Predicted)
Density: 1?+-.0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
solubility: Chloroform (Slightly, Heated), DMSO (Soluble), Methanol (Slightly)
pka: 4.59±0.10(Predicted)
form: Solid
color: Off-White
Water Solubility: Partly miscible in water.
Sensitive: Air Sensitive
InChI: InChI=1S/C22H20O2S/c23-21(24)16-17-25-22(18-10-4-1-5-11-18,19-12-6-2-7-13-19)20-14-8-3-9-15-20/h1-15H,16-17H2,(H,23,24)
InChIKey: AECGEIVNZGQBJT-UHFFFAOYSA-N
SMILES: C(O)(=O)CCSC(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1
CAS DataBase Reference: 27144-18-9(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22-36/37/38
Safety Statements: 26
WGK Germany: 3
F: 10-23

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 53695
Product name: 3-(Tritylthio)propionic acid
Purity: ≥97.0% (T)
Packaging: 1g
Price: $136
Updated: 2025/07/31

Sigma-Aldrich

Product number: 53695
Product name: 3-(Tritylthio)propionic acid
Purity: ≥97.0% (T)
Packaging: 1g-f
Price: $117
Updated: 2021/12/16

TCI Chemical

Product number: T2179
Product name: 3-(Tritylthio)propanoic Acid
Packaging: 5G
Price: $30
Updated: 2025/07/31

TCI Chemical

Product number: T2179
Product name: 3-(Tritylthio)propanoic Acid
Packaging: 25G
Price: $90
Updated: 2025/07/31

TRC

Product number: T889475
Product name: 3-TritylsulfanylpropionicAcid
Packaging: 5g
Price: $60
Updated: 2021/12/16

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S-TRITYL-3-MERCAPTOPROPIONIC ACID Chemical Properties,Usage,Production

Chemical Properties

White to off-white powder

Uses

Preparation and structural modification of 3-Tritylsulfanylpropionic Acid possesses antileukemic activity against leukemia.

Synthesis

76-84-6

107-96-0

27144-18-9

General procedure for the synthesis of 3-(triphenylmethylthio)propionic acid from triphenylmethanol and 3-mercaptopropionic acid: 1. 100 g of 3-mercaptopropionic acid (942.15 mmol) was dissolved in 300 mL of glacial acetic acid at room temperature. 2. 245.27 g of triphenylmethanol (942.15 mmol) was dissolved in 736.79 mL of tetrahydrofuran (THF) at room temperature. 3. Slowly add the solution obtained from step 1 to the solution from step 2. 4. 16.62 g of concentrated sulfuric acid (98%, 169.587 mmol) is added slowly and dropwise at 28° C to 30° C. The reaction mixture is insulated. 5. The reaction mixture was stirred under insulating conditions for 4 hours. 6. Upon completion of the reaction, 360 g of solid crude product was obtained by filtration. 7. The crude product was dissolved in 720 mL of N,N-dimethylformamide (DMF). 8. 5 times the volume of water was added to the solution, filtered and dried to give 295.5 g of refined product in 90% yield. 9. The structure of the product was confirmed by infrared spectroscopy (IR) and nuclear magnetic resonance (NMR).

References

[1] Organic Letters, 2017, vol. 19, # 12, p. 3195 - 3198
[2] Patent: CN106380430, 2017, A. Location in patent: Paragraph 0017; 0018; 0019; 0020
[3] Chemical Communications, 2014, vol. 50, # 35, p. 4571 - 4574
[4] Australian Journal of Chemistry, 1990, vol. 43, # 3, p. 629 - 634
[5] Journal of Medicinal Chemistry, 2000, vol. 43, # 8, p. 1448 - 1455

S-TRITYL-3-MERCAPTOPROPIONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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S-TRITYL-3-MERCAPTOPROPIONIC ACID Suppliers

China 195 Germany 3 India 5 Japan 2 Switzerland 1 United Kingdom 3 United States 15 Global 224

J & K SCIENTIFIC LTD.

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View Lastest Price from S-TRITYL-3-MERCAPTOPROPIONIC ACID manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 3-(Tritylthio)propionic acid 27144-18-9
Price: US $3.00-9.00/KG
Min. Order: 0.1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2025-06-23

Hebei Chuanghai Biotechnology Co., Ltd

Product: S-TRITYL-3-MERCAPTOPROPIONIC ACID 27144-18-9
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2024-11-07

Henan Bao Enluo International TradeCo.，LTD

Product: S-TRITYL-3-MERCAPTOPROPIONIC ACID 27144-18-9
Price: US $50.00/kg
Min. Order: 1kg
Purity: 99.9%
Supply Ability: 10000MT
Release date: 2023-08-15

27144-18-9, S-TRITYL-3-MERCAPTOPROPIONIC ACIDRelated Search:

N-Boc-S-Trityl-L-cysteine N-Fmoc-S-trityl-D-cysteine FMOC-CYS(MMT)-OH S-TRITYL-3-MERCAPTOPROPIONIC ACID FMOC-CYS(TRT)-OPFP FMOC-D-PEN(TRT)-OH FMOC-S-trityl-L-cysteine Fmoc-S-Trityl-L-penicillamine S-Trityl-L-cysteine 3-Mercaptopropionic acid TRT-CYS(TRT)-OH H-PEN(TRT)-OH TRT-CYS(TRT)-OH DEA BOC-PEN(TRT)-OH Fmoc-D-Cys(Trt)- OPfp BOC-D-PEN(TRT)-OH H-D-PEN(TRT)-OH AC-CYS(TRT)-OH

3-TRITYLMERCAPTO PROPIONIC ACID

3-TRITYLSULFANYL-PROPIONIC ACID

S-TRITYL-3-MERCAPTOPROPIONIC ACID

S-TRITYL-BETA-MERCAPTOPROPIONIC ACID

(TRT)SCH2CH2COOH

3-(Tritylthio)propionic acid

S-TRITYL-3-MERCAPTOPROPIONIC ACID 98+%

Mpa(Trt)

3-Tritymercaptopropionic]

3-Tritylmercapto-Propionic acid (Trt)SCH2CH2COOH

S-TRITYL-B-MERCAPTOPROPIONIC ACID

S-TRITYL-3-MERCAPTOPROPIONIC

3-MPA(Trt)

3-tritymercapto-propiomic

Nsc96707

Mpa(Trt)-OH

3-[(triphenylMethyl)sulfanyl]propanoic acid

Mpr(Trt)-OH, Mpa(Trt)-OH, S-Trityl-deaMino-cysteine

3-(Tritylthio)propanoic acid

Tritylthio)propionic ac

3-(threephenyl Methylsulfhydryl)propionic acid

MPR(TRT)-OH

Mpr(trt)

3-(Tritylthio)propionic acid≥ 98% (HPLC)

3-tritylsulfanylpropanoic acid

3-(Tritylthio)propionic acid >=97.0% (T)

Mpa(Trt) 3-Tritylmercapto-Propionic acid (Trt)SCH2CH2COOH

3-[[2-(diphenylmethyl)phenyl]thio]propanoic acid

Propanoic acid, 3-[(triphenylmethyl)thio]-

3-tritylsulfanylpropanoicaci

S-trityl-β-mercaptopropionic acid

3-(Tritylthio)propionic acid, 97%,

3-[(Triphenylmethyl)thio]propanoic acid

Glycine Impurity 14

Valine Impurity 31

Trt-Mpa-OH

27144-18-9

C22H20O2S

Organic Building Blocks

C13 to C42+

Carbonyl Compounds

Carboxylic Acids

Building Blocks

Other Reagents