Fmoc-S-Trityl-L-penicillamine

Product Name: Fmoc-S-Trityl-L-penicillamine
CAS No.: 201531-88-6
Chemical Name: Fmoc-S-Trityl-L-penicillamine
Synonyms: FMOC-PEN(TRT)-OH;FMoc-pen(trt);FMOC-L-PEN(TRT)-OH;Fmoc-L-Pen（Ttr）-OH;FMOC-CYSME 2(TRT)-OH;FMOC-PEN(TRT)-OH 1 G;FMOC-PEN(TRT)-OH 5 G;Fmoc-Pen(Trt)-OH, >=99%;FMOC-PENICILLAMINE(TRT)-OH;FMOC-Pen(Trt)-OHC39H35NO4S
CBNumber: CB6175744
Molecular Formula: C39H35NO4S
Formula Weight: 613.76
MOL File: 201531-88-6.mol

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Fmoc-S-Trityl-L-penicillamine Property

Boiling point:: 768.8±60.0 °C(Predicted)
alpha: 33 º (c=1 in methanol)
Density: 1.242±0.06 g/cm3(Predicted)
storage temp.: Store at -15°C to -25°C.
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: Powder
pka: 3.70±0.10(Predicted)
color: White to off-white
optical activity: [α]/D +33±2°, c = 1 in methanol
Major Application: peptide synthesis
InChI: InChI=1S/C39H35NO4S/c1-38(2,45-39(27-16-6-3-7-17-27,28-18-8-4-9-19-28)29-20-10-5-11-21-29)35(36(41)42)40-37(43)44-26-34-32-24-14-12-22-30(32)31-23-13-15-25-33(31)34/h3-25,34-35H,26H2,1-2H3,(H,40,43)(H,41,42)/t35-/m1/s1
InChIKey: XSGMGAINOILNJR-PGUFJCEWSA-N
SMILES: C(O)(=O)[C@H](C(SC(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1)(C)C)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
CAS DataBase Reference: 201531-88-6(CAS DataBase Reference)

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Safety

WGK Germany: 3
HS Code: 2930 90 16
HazardClass: IRRITANT
Storage Class: 11 - Combustible Solids

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.52339
Product name: Fmoc-Pen(Trt)-OH
Purity: Novabiochem?
Packaging: 1g
Price: $187
Updated: 2025/07/31

Sigma-Aldrich

Product number: 8.52339
Product name: Fmoc-Pen(Trt)-OH
Purity: Novabiochem?
Packaging: 5G
Price: $736
Updated: 2025/07/31

Sigma-Aldrich

Product number: 670642
Product name: Fmoc-Pen(Trt)-OH
Purity: 96%
Packaging: 500mg
Price: $151
Updated: 2025/07/31

TRC

Product number: F861075
Product name: Fmoc-s-trityl-l-penicillamine
Packaging: 250mg
Price: $165
Updated: 2021/12/16

Usbiological

Product number: 277050
Product name: Fmoc-S-trityl-L-penicillamine
Packaging: 250mg
Price: $355
Updated: 2021/12/16

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Fmoc-S-Trityl-L-penicillamine Chemical Properties,Usage,Production

Description

Fmoc-S-trityl-L-penicillamine is a coordination compound that contains a thiolate and amide group. It has been used as a model system for studying the interaction between proteins and metal ions, with the cyclic structure mimicking the active site of enzymes. The coordination of Fmoc-S-trityl-L-penicillamine to proteins is affected by trypsin, an enzyme that cleaves peptides at carboxyl side chains. Trypsin can also lead to dehydration of Fmoc-S-trityl-L-penicillamine, forming an eliminations product. This compound also reacts with lysine residues in proteins, resulting in an alkene byproduct that can be removed by hydrogenation.

Chemical Properties

White to off-white powder

Uses

Fmoc-s-trityl-l-penicillamine is a new peptidomimetic furin inhibitors with potent anti-infectious activity.

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

Synthesis

11mmol, 1.1eq Fmoc-Cl was added dropwise to a solution of dichloromethane containing 10mmol, 1eq of S-trityl-L-cysteine and 30ml of sodium bicarbonate containing 13mmol, 1.3eq of sodium bicarbonate under an ice-salt bath, and the reaction solution was brought up to room temperature after dropwise addition. The reaction was finished for 12h. The reaction solution was filtered and the filter cake plus washed with dichloromethane and the organic phase was combined. The organic phase was washed once with 20 ml of dilute sodium bicarbonate solution, 20 ml, 0.5 M dilute hydrochloric acid and 30 ml of saturated saline, then the organic phase was dried with anhydrous sodium sulfate for 2h, filtered, spin-dried solvent, the target product Fmoc-S-trityl-L-penicillamine was obtained.

Fmoc-S-Trityl-L-penicillamine Preparation Products And Raw materials

Raw materials

Preparation Products

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Fmoc-S-Trityl-L-penicillamine Suppliers

China 208 Germany 4 India 2 Japan 2 Switzerland 1 United Kingdom 2 United States 17 Global 236

SICHUAN TONGSHENG BIOPHARMACEUTICAL CO., LTD

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Apeloa Pharmaceutical Co., Ltd.

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GL Biochem (Shanghai) Ltd

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Shanghai GL Peptide Ltd.

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Shanghai Menglan Pharmaceutical Technology Co., Ltd

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Shandong fen Boyu Biotechnology Co.,LTD

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Tiantai Yisheng Biochemical Technology Co., Ltd

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CAS Aldone(Dalian) Pharmaceutical Science and Technology Co, Ltd.

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Shanghai Galedo Biotechnology Co., Ltd.

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Xi'an Manareco New Materials Co., Ltd.

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View Lastest Price from Fmoc-S-Trityl-L-penicillamine manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: Fmoc-S-Trityl-L-penicillamine 201531-88-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-10-08

Henan Fengda Chemical Co., Ltd

Product: Fmoc-S-Trityl-L-penicillamine 201531-88-6
Price: US $8.00-2.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-24

GL Biochem (Shanghai) Ltd.

Product: Fmoc-Pen(Trt)-OH 201531-88-6
Price: US $0.00-0.00/KG
Min. Order: 5g
Purity: 98%; 99%
Supply Ability: 500 Kg
Release date: 2021-04-23

201531-88-6, Fmoc-S-Trityl-L-penicillamineRelated Search:

p-Toluic acid 1,1'-Carbonyldiimidazole Triphenylmethyl Chloride Fmoc-N'-methyltrityl-L-lysine Trityl candesartan cilexetil 9-Fluorenylmethyl chloroformate L-Penicillamine Fmoc-8-amino-3,6-dioxaoctanoic acid Dimethyl fumarate FMOC-S-trityl-L-cysteine FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE Fmoc-Phe(4-CF2H)-OH L-Phenylalanine, 3-[(1,1-dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]- Fmoc-OSu D-Penicillamine FMOC-THR(TBU)-OL FMOC-ASU-OH Fmoc-phe(2-Ae-Z)-OH

FMOC-PEN(TRT)-OH

FMOC-PENICILLAMINE(TRT)-OH

FMOC-S-TRITYL-BETA,BETA-DIMETHYL-L-CYS-OH

FMOC-S-TRITYL-L-PENICILLAMINE

FMOC-CYSME 2(TRT)-OH

FMOC-L-PEN(TRT)-OH

FMOC-BETA,BETA-DIMETHYL-CYS(TRT)-OH

N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-S-TRITYL-3,3-DIMETHYL-L-CYSTEINE

N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-S-TRITYL-L-PENICILLAMINE

N-ALPHA-FMOC-S-TRITYL-L-PENICILLAMINE

N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-S-TRITYL-L-PENICILLAMINE

FMoc-b,b-diMethyl-Cys(Trt)-OH

Fmoc-β,β-dimethyl-Cys(Trt)-OH, Fmoc-S-trityl-L-penicillamine

FMOC-Pen(Trt)-OHC39H35NO4S

(R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-methyl-3-(tritylthio)butanoic acid

Fmoc-β,β-dimethyl-Cys(Trt)-OH

N-alpha-(9-Fluorenylmethyloxycarbonyl)-S-trityl-L-penicillamine, Fmoc-beta,beta-dimethyl-L-Cys(Trt)-OH

N-Fmoc-3-(trityl-thio)-L-valine

2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-3-methyl-3-[(triphenylmethyl)thio]butanoic acid

(2R)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-methyl-3-[(triphenylmethyl)sulfanyl]butanoic acid

FMoc-pen(trt)

Fmoc-S-trityl-L-penicillamine≥ 98% (HPLC)

Fmoc-S-trityl-β,β-dimethyl-L-Cys-OH

L-Valine,N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-[(triphenylmethyl)thio]-

(9H-Fluoren-9-yl)MethOxy]Carbonyl Pen(Trt)-OH

Fmoc-Pen(Trt)-OH (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-methyl-3-(tritylthio)butanoic acid

Fmoc-Pen(Trt)-OH, >=99%

FMOC-PEN(TRT)-OH 1 G

FMOC-PEN(TRT)-OH 5 G

(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methyl-3-tritylsulfanylbutanoicaci

Fmoc-S-Trityl-L-penicillamine USP/EP/BP

(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methyl-3-tritylsulfanylbutanoic acid

Fmoc-Pen(Trt)-OH?201531-88-6

201531-88-6---Fmoc-S-Trityl-L-penicillamine

Fmoc-β,β-dimethyl-Cys(Trt)-OH, Fmoc-S-trityl-L-penicillamine

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-[(triphenylmethyl)thio]-L-valine

(R)-2-((((9H-fluorene-9-yl)methoxy)oxo)amino)-3-methyl-3-(tribenzylsulfyl)butanoic acid

Fmoc-L-Pen（Ttr）-OH

201531-88-6

Unusual Amino Acids

Fmoc-Amino acid series