2-Bromo-6-fluorobenzaldehyde

Product Name: 2-Bromo-6-fluorobenzaldehyde
CAS No.: 360575-28-6
Chemical Name: 2-Bromo-6-fluorobenzaldehyde
Synonyms: 2-Bromo-6-fL;2-Bromo-6-flurobenzaldehyde;2-BROMO-6-FLUOROBENZALDEHYDE;Benzaldehyde,2-broMo-6-fluoro-;2-BroMo-6-fluorobenzaldehyde 96%;2-BroMo-6-fluorobenzaldehyde, 95+%;2-BROMO-6-FLUOROBENZENECARBALDEHYDE;Structure Search 2-Bromo-4-fluorobenzaldehyde;2-BROMO-6-FLUOROBENZALDEHYDE CAS: 360575-28-6;2-Bromo-6-fluorobenzaldehyde ISO 9001：2015 REACH
CBNumber: CB5249008
Molecular Formula: C7H4BrFO
Formula Weight: 203.01
MOL File: 360575-28-6.mol

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2-Bromo-6-fluorobenzaldehyde Property

Melting point:: 43-47 °C
Boiling point:: 100-102℃/8mm
Density: 1.70
Flash point:: >110°(230°F)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
solubility: Chlorofrom (Slightly), Ethyl Acetate (Slightly)
form: Solid
Appearance: White to light brown Solid
Water Solubility: Slightly soluble in water.
Sensitive: Light Sensitive
InChI: InChI=1S/C7H4BrFO/c8-6-2-1-3-7(9)5(6)4-10/h1-4H
InChIKey: PJNILWKRAKKEQM-UHFFFAOYSA-N
SMILES: C(=O)C1=C(F)C=CC=C1Br
CAS DataBase Reference: 360575-28-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 22-36/37/38
Safety Statements: 26-36
RIDADR: UN 3335
WGK Germany: 3
Hazard Note: Irritant
HazardClass: 9
HS Code: 29130000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 709824
Product name: 2-Bromo-6-fluorobenzaldehyde
Purity: 96%
Packaging: 1g
Price: $38.2
Updated: 2025/07/31

TRC

Product number: B683305
Product name: 2-Bromo-6-fluorobenzaldehyde
Packaging: 1g
Price: $45
Updated: 2021/12/16

TRC

Product number: B683305
Product name: 2-Bromo-6-fluorobenzaldehyde
Packaging: 10g
Price: $110
Updated: 2021/12/16

Oakwood

Product number: 036235
Product name: 2-Bromo-6-fluorobenzaldehyde
Packaging: 1g
Price: $10
Updated: 2021/12/16

Apolloscientific

Product number: PC7441
Product name: 2-Bromo-6-fluorobenzaldehyde
Purity: 97%
Packaging: 5g
Price: $16
Updated: 2021/12/16

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2-Bromo-6-fluorobenzaldehyde Chemical Properties,Usage,Production

Uses

It is a important raw material and intermediate used in organic synthesis agrochemical, pharmaceutical and dyestuff field.

Synthesis

1073-06-9

68-12-2

360575-28-6

To a stirred solution of iPr2NH (2.25 mL, 1.63 g, 16.1 mmol) in THF (20 mL) containing a 50 mL three-necked flask under the protection of dry argon gas was added dropwise nBuLi (6.3 mL, 2.35 M in hexane, 14.7 mmol). The reaction mixture was stirred at 0°C for 10 min. Subsequently, after continued stirring at 0°C for 20 min, the mixture was cooled to -78°C and a solution of 1-bromo-3-fluorobenzene (2.45 g, 14.0 mmol) in THF (10 mL) was added dropwise over a 12-minute period, maintaining the temperature in the range of -85 to -75°C, to give a deep red solution. After stirring at -78°C for 1 h, a THF (7 mL) solution of DMF (1.32 g, 18.2 mmol) was added dropwise over 5 min and stirring was continued for 1 h at -78°C. The reaction mixture was quenched with AcOH (2.5 mL) and slowly warmed to room temperature. The reaction mixture was poured into a mixture of 0.2 M HCl (40 mL) and MeOAc (50 mL) and the organic layer was separated. The aqueous layer was extracted with MeOAc (30 mL), and the combined organic phases were washed with brine (60 mL), dried over Na2SO4, filtered and concentrated under reduced pressure to give an orange colored oil. The oil was purified by recrystallization from hexane to afford the target product 2-bromo-6-fluorobenzaldehyde SI-1f (2.31 g, 11.4 mmol, 81% yield).

References

[1] Journal of Organic Chemistry, 2013, vol. 78, # 15, p. 7741 - 7748
[2] Tetrahedron Letters, 2016, vol. 57, # 1, p. 11 - 14
[3] Patent: US2017/158680, 2017, A1. Location in patent: Paragraph 0361; 0362; 0363
[4] Patent: WO2014/169167, 2014, A1. Location in patent: Page/Page column 57; 58
[5] Bioorganic and Medicinal Chemistry Letters, 2005, vol. 15, # 12, p. 2998 - 3001

2-Bromo-6-fluorobenzaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Bromo-6-fluorobenzaldehyde Suppliers

China 287 India 5 Italy 1 United Kingdom 9 United States 29 Global 331

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View Lastest Price from 2-Bromo-6-fluorobenzaldehyde manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-Bromo-6-fluorobenzaldehyde 360575-28-6
Price: US $30.00-10.00/KG
Min. Order: 50KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-29

Hebei Yanxi Chemical Co., Ltd.

Product: 2-Bromo-6-fluorobenzaldehyde 360575-28-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 20 tons
Release date: 2023-11-27

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2-Bromo-6-fluorobenzaldehyde 360575-28-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

360575-28-6, 2-Bromo-6-fluorobenzaldehydeRelated Search:

2-Bromo-6-fluorobenzaldehyde 2-Bromo-3,4,5,6-tetrafluorobenzoic acid 6-bromo-2-fluoro-3-methoxybenzaldehyde 2-Bromo-6-fluorobenzoic acid 2-BROMO-3,4,5,6-TETRAFLUOROBENZOYL CHLORIDE 2-BROMO-5-FLUOROBENZALDEHYDE 2-BROMO-3-FLUOROBENZALDEHYDE 3-Bromo-5-fluorobenzaldehyde 98%,3-Bromo-5-fluorobenzaldehyde98%,3-BROMO-5-FLUOROBENZALDEHYDE 4-Bromo-2-fluorobenzaldehyde98%,4-Bromo-2-fluorobenzaldehyde 98%,4-Bromo-2-Fluorobenzaldehyde 2-Fluoro-4-Bromobenzaldehyde,4-BROMO-2-FLUOROBENZALDEHYDE 2-BROMO-3-FLUOROBENZALDEHYDE 2-BROMO-4-FLUOROBENZALDEHYDE 3-BROMO-4-FLUOROBENZALDEHYDE,3-Bromo-4-fluorobenzaldehyde98%,3-Bromo-4-fluorobenzaldehyde 98% 4-Bromo-3-fluorobenzaldehyde98%,4-Bromo-3-fluorobenzaldehyde 98%,4-BROMO-3-FLUOROBENZALDEHYDE 5-BROMO-2-FLUOROBENZALDEHYDE,5-Bromo-2-Fluorobenzaldehyde 2-Fluoro-5-Bromobenzaldehyde,5-Bromo-2-fluorobenzaldehyde 98%,5-Bromo-2-fluorobenzaldehyde98% 3,6-dibromo-2-fluorobenzaldehyde 6-Bromo-2,3,4-Trifluorobenzoic Acid 2,3-DIFLUORO-6-BROMOBENZOIC ACID 2,4-DIBROMO-6-FLUOROBENZOYL CHLORIDE

2-BROMO-6-FLUOROBENZALDEHYDE

2-BROMO-6-FLUOROBENZENECARBALDEHYDE

2-BroMo-6-fluorobenzaldehyde 96%

2-BroMo-6-fluorobenzaldehyde, 95+%

Benzaldehyde,2-broMo-6-fluoro-

Structure Search 2-Bromo-4-fluorobenzaldehyde

2-Bromo-6-fL

2-BROMO-6-FLUOROBENZALDEHYDE CAS: 360575-28-6

2-Bromo-6-fluorobenzaldehyde ISO 9001：2015 REACH

2-Bromo-6-flurobenzaldehyde

6-BroMo-2-fluorobe6-BroMo-2-fluorobenzaldehydenzaldehyde

360575-28-6

36057-28-6

Adehydes, Acetals & Ketones

Bromine Compounds

Fluorine Compounds

Benzene series

Benzaldehyde