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PHA-793887

Product Name
PHA-793887
CAS No.
718630-59-2
Chemical Name
PHA-793887
Synonyms
CS-350;PHA-793887;PHA-793887 USP/EP/BP;PHA-793887;PHA793887;3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c];N-(6,6-dimethyl-5-(1-methylpiperidine-4-carbonyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-3-methylbutanamide;N-(6,6-dimethyl-5-(1-methylpiperidine-4-carbonyl)-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-3-methylbutanamide;3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide;Butanamide, 3-methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]-;PHA-793887 3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide
CBNumber
CB52516232
Molecular Formula
C19H31N5O2
Formula Weight
361.48
MOL File
718630-59-2.mol
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PHA-793887 Property

Melting point:
>147°C (dec.)
Boiling point:
596.2±50.0 °C(Predicted)
Density 
1.176±0.06 g/cm3(Predicted)
storage temp. 
Hygroscopic, Refrigerator, under inert atmosphere
solubility 
DMSO (Slightly), Methanol(Slightly)
pka
13.74±0.40(Predicted)
form 
Solid
color 
Off-White to Pale Yellow
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
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N-Bromosuccinimide Price

Cayman Chemical
Product number
18388
Product name
PHA-793887
Purity
≥95%
Packaging
5mg
Price
$46
Updated
2024/03/01
Cayman Chemical
Product number
18388
Product name
PHA-793887
Purity
≥95%
Packaging
1mg
Price
$43
Updated
2023/06/20
Cayman Chemical
Product number
18388
Product name
PHA-793887
Purity
≥95%
Packaging
10mg
Price
$88
Updated
2024/03/01
Cayman Chemical
Product number
18388
Product name
PHA-793887
Purity
≥95%
Packaging
50mg
Price
$230
Updated
2024/03/01
TRC
Product number
P294480
Product name
PHA-793887
Packaging
10mg
Price
$225
Updated
2021/12/16
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PHA-793887 Chemical Properties,Usage,Production

Chemical Properties

White to Off-White Solid

Uses

PHA-793887 is a potent CDK (cyclin-dependent kinase) inhibitor. Recent studies shows that PHA-793887 has promising therapeutic activity against acute leukemias in vitro and in vivo. PHA-793887 was used to successfully modulate E2F transcriptional factor-dependent cell cycle, DNA replication, mitosis and apoptosis related gene in both tumors and skin biopsy from patients with solid tumors.

Definition

ChEBI: N-[6,6-dimethyl-5-[(1-methyl-4-piperidinyl)-oxomethyl]-1,4-dihydropyrrolo[3,4-c]pyrazol-3-yl]-3-methylbutanamide is a piperidinecarboxamide.

target

CDK5/p25

PHA-793887 Preparation Products And Raw materials

Raw materials

Preparation Products

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PHA-793887 Suppliers

Canada 1 China 76 China Hong Kong 1 India 2 United Kingdom 1 United States 14 Global 95
Toronto Research Chemicals
Tel
--
Fax
--
Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
71
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View Lastest Price from PHA-793887 manufacturers

Career Henan Chemical Co
Product
3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide 718630-59-2
Price
US $6.68/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
1kg-1000kg
Release date
2020-01-08

718630-59-2, PHA-793887Related Search:

Danusertib N-Methylbenzylamine 2-Methylaminoethanol N-Methyl pyrrole N-Methylbenzamide 2,2-DIMETHYLTETRAHYDROFURAN CX-4945 SNS-032 (2S)-1-[3-Ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-2-piperidineethanol Veliparib Roscovitine Olaparib

  • N-(6,6-dimethyl-5-(1-methylpiperidine-4-carbonyl)-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-3-methylbutanamide
  • CS-350
  • 3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide
  • PHA-793887
  • N-(6,6-dimethyl-5-(1-methylpiperidine-4-carbonyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-3-methylbutanamide
  • 3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide PHA-793887
  • PHA-793887 3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide
  • PHA-793887;PHA793887
  • 3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]
  • Butanamide, 3-methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]-
  • PHA-793887 USP/EP/BP
  • 718630-59-2
  • Inhibitors
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Protein Kinase Inhibitors and Activators
  • Apis