2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid

ChemicalBook > CAS DataBase List > 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid

2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid

Product Name: 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid
CAS No.: 890842-28-1
Chemical Name: 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid
Synonyms: CS-1142;GSK 650394;GSK650394 (Free base);SGK inhibitor GS650394;6-O-α-D-Glucopyranosyl-D-glucose;2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid;Benzoic acid, 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-
CBNumber: CB52518968
Molecular Formula: C25H22N2O2
Formula Weight: 382.45
MOL File: 890842-28-1.mol

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2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Property

storage temp.: room temp
solubility: DMSO: soluble20mg/mL, clear
form: powder
color: white to beige

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0773
Product name: GSK-650394
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $150
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0773
Product name: GSK-650394
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $598
Updated: 2024/03/01

Cayman Chemical

Product number: 17001
Product name: GSK650394
Purity: ≥98%
Packaging: 5mg
Price: $106
Updated: 2024/03/01

Cayman Chemical

Product number: 17001
Product name: GSK650394
Purity: ≥98%
Packaging: 10mg
Price: $198
Updated: 2024/03/01

Cayman Chemical

Product number: 17001
Product name: GSK650394
Purity: ≥98%
Packaging: 25mg
Price: $467
Updated: 2024/03/01

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2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Chemical Properties,Usage,Production

Uses

GSK-650394 has been used as a serum and glucocorticoid-activated kinase (SGK1) inhibitor.

Definition

ChEBI: 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid is a phenylpyridine.

Biochem/physiol Actions

GSK-650394 has an IC50 value of 62?nM for serum and glucocorticoid-activated kinase-1 (SGK1) and 103?nM for SGK2. It has an ability to stop viral replication at concentrations that are nontoxic to cells.

storage

Store at RT

2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Suppliers

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GSK650394 (Free base)

2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid

GSK 650394

SGK inhibitor GS650394

CS-1142

Benzoic acid, 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-

6-O-α-D-Glucopyranosyl-D-glucose

890842-28-1

Inhibitors