ChemicalBook > CAS DataBase List > Carbamic acid, N-(cis-3-aminocyclobutyl)-, 1,1-dimethylethyl ester

Carbamic acid, N-(cis-3-aminocyclobutyl)-, 1,1-dimethylethyl ester

Product Name
Carbamic acid, N-(cis-3-aminocyclobutyl)-, 1,1-dimethylethyl ester
CAS No.
1212395-34-0
Chemical Name
Carbamic acid, N-(cis-3-aminocyclobutyl)-, 1,1-dimethylethyl ester
Synonyms
tert-butyl ((1s,3s)-3-aMinocyclobutyl)carbaMate;cis-N-Boc-1,3-diaMinocyclobutane;cis-N1-Boc-cyclobutane-1,3-diamine;cis-tert-butyl-3-aMinocyclobutylcarbaMate;cis-tert-Butyl 3-aMinocyclobutanecarbaMate;tert-Butyl N-(3-aMinocyclobutyl)-carbaMate;tert-butyl (cis-3-aMinocyclobutyl)carbaMate;tert-ButylN-(cis-3-aminocyclobutyl)carbamate;cis tert-Butyl N-(3-aMinocyclobutyl)carbaMate;real- TERT-BUTYL N-(3-AMINOCYCLOBUTYL)CARBAMATE, cis
CBNumber
CB52525258
Molecular Formula
C9H18N2O2
Formula Weight
186.25
MOL File
1212395-34-0.mol
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Carbamic acid, N-(cis-3-aminocyclobutyl)-, 1,1-dimethylethyl ester Property

Boiling point:
285.8±29.0 °C(Predicted)
Density 
1.06±0.1 g/cm3(Predicted)
storage temp. 
2-8°C, protect from light
pka
12.32±0.40(Predicted)
Appearance
White to yellow Solid
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Safety

HS Code 
2924297099
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Apolloscientific
Product number
OR308090
Product name
tert-Butyl (cis-3-aminocyclobutyl)carbamate
Packaging
100mg
Price
$237
Updated
2021/12/16
Matrix Scientific
Product number
068481
Product name
cis tert-Butyl N-(3-aminocyclobutyl)carbamate
Purity
>95%
Packaging
500mg
Price
$295
Updated
2021/12/16
Apolloscientific
Product number
OR308090
Product name
tert-Butyl (cis-3-aminocyclobutyl)carbamate
Packaging
250mg
Price
$412
Updated
2021/12/16
Matrix Scientific
Product number
068481
Product name
cis tert-Butyl N-(3-aminocyclobutyl)carbamate
Purity
>95%
Packaging
1g
Price
$450
Updated
2021/12/16
SynQuest Laboratories
Product number
4256-1-41
Product name
tert-Butyl (cis-3-aminocyclobutyl)carbamate
Packaging
1g
Price
$575
Updated
2021/12/16
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Carbamic acid, N-(cis-3-aminocyclobutyl)-, 1,1-dimethylethyl ester Chemical Properties,Usage,Production

Synthesis

1239589-57-1

1212395-34-0

Tert-butyl cis-3-azido cyclobutylcarbamate (15.00 g, 70.7 mmol) was used as a feedstock and mixed with 10 wt% palladium/activated carbon catalyst (dry basis) in a 1000 mL three-neck flask. The system was flushed with N2 and sealed with methanol (200 mL) and 2 M ammonia (3.76 mL, 35.3 mmol, Sigma-Aldrich Chemical Company, Inc.). The flask was evacuated and filled with hydrogen (balloon supply). The reaction mixture was stirred at room temperature for 18 hours and subsequently filtered. The filtrate was concentrated under reduced pressure to afford tert-butyl cis-3-amino-1-cyclobutylcarbamate (11.1 g, 59.6 mmol, 84% yield), which could be used in subsequent steps without further purification.

References

[1] Journal of Organic Chemistry, 2010, vol. 75, # 17, p. 5941 - 5952
[2] Patent: US2013/225552, 2013, A1. Location in patent: Paragraph 0990

Carbamic acid, N-(cis-3-aminocyclobutyl)-, 1,1-dimethylethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Carbamic acid, N-(cis-3-aminocyclobutyl)-, 1,1-dimethylethyl ester Suppliers

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1212395-34-0, Carbamic acid, N-(cis-3-aminocyclobutyl)-, 1,1-dimethylethyl esterRelated Search:

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  • cis tert-Butyl N-(3-aminocyclobutyl)carbamate - B0661
  • tert-butyl (cis-3-aMinocyclobutyl)carbaMate
  • tert-Butyl N-(3-aMinocyclobutyl)-carbaMate
  • cis-tert-butyl-3-aMinocyclobutylcarbaMate
  • cis tert-Butyl N-(3-aMinocyclobutyl)carbaMate
  • cis-N-Boc-1,3-diaMinocyclobutane
  • tert-butyl ((1s,3s)-3-aMinocyclobutyl)carbaMate
  • cis-tert-Butyl 3-aMinocyclobutanecarbaMate
  • tert-ButylN-(cis-3-aminocyclobutyl)carbamate
  • cis-N1-Boc-cyclobutane-1,3-diamine
  • real- TERT-BUTYL N-(3-AMINOCYCLOBUTYL)CARBAMATE, cis
  • Carbamic acid, N-(cis-3-aminocyclobutyl)-, 1,1-dimethylethyl ester
  • 1212395-34-0