ChemicalBook > CAS DataBase List > 1H-Pyrazolo[3,4-b]pyridine-3-carboximidamide, 1-[(2-fluorophenyl)methyl]-, hydrochloride (1:1)

1H-Pyrazolo[3,4-b]pyridine-3-carboximidamide, 1-[(2-fluorophenyl)methyl]-, hydrochloride (1:1)

Product Name
1H-Pyrazolo[3,4-b]pyridine-3-carboximidamide, 1-[(2-fluorophenyl)methyl]-, hydrochloride (1:1)
CAS No.
256499-19-1
Chemical Name
1H-Pyrazolo[3,4-b]pyridine-3-carboximidamide, 1-[(2-fluorophenyl)methyl]-, hydrochloride (1:1)
Synonyms
1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide hydrochloride;1-(2-Fluoro-benzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxaMidine hydrochloride;Riociguat-10;Riociguat Impurity 3 HCl;Riociguat EP Impurity 10;Riociguat Impurity 2 HCl;Riociguanidine Intermediate;1-(2-Fluoro-benzyl)-1H-py...;1-(2-fluorobenzyl)-1H-pyrazolo;1-(2-Fluoro-benzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamidine
CBNumber
CB52525708
Molecular Formula
C14H13ClFN5
Formula Weight
305.74
MOL File
256499-19-1.mol
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1H-Pyrazolo[3,4-b]pyridine-3-carboximidamide, 1-[(2-fluorophenyl)methyl]-, hydrochloride (1:1) Property

Melting point:
247-249oC
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
White
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
F588235
Product name
1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamideHydrochloride
Packaging
250mg
Price
$50
Updated
2021/12/16
TRC
Product number
F588235
Product name
1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamideHydrochloride
Packaging
5g
Price
$250
Updated
2021/12/16
Matrix Scientific
Product number
068862
Product name
1-(2-Fluoro-benzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamidine hydrochloride
Purity
>95%
Packaging
5g
Price
$270
Updated
2021/12/16
AK Scientific
Product number
Y8461
Product name
1-(2-Fluoro-benzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamidinehydrochloride
Packaging
5g
Price
$311
Updated
2021/12/16
Matrix Scientific
Product number
068862
Product name
1-(2-Fluoro-benzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamidine hydrochloride
Purity
>95%
Packaging
25g
Price
$710
Updated
2021/12/16
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1H-Pyrazolo[3,4-b]pyridine-3-carboximidamide, 1-[(2-fluorophenyl)methyl]-, hydrochloride (1:1) Chemical Properties,Usage,Production

Uses

1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide Hydrochloride is a key intermediate in the synthesis of Riociguat, a potent, oral stimulator of soluble guanylate cyclase for the treatment of pulmonary hypertension.

1H-Pyrazolo[3,4-b]pyridine-3-carboximidamide, 1-[(2-fluorophenyl)methyl]-, hydrochloride (1:1) Preparation Products And Raw materials

Raw materials

Preparation Products

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1H-Pyrazolo[3,4-b]pyridine-3-carboximidamide, 1-[(2-fluorophenyl)methyl]-, hydrochloride (1:1) Suppliers

China 190 India 5 United States 4 Global 199
Nanjing FuRuisi Medical Technology Co., Ltd.
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025-83221260
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02583221260
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renqing401@163.com
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China
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Hefei Leaf Biotech Co.,Ltd.
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Jia Xing Isenchem Co.,Ltd
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0573-85285100 18627885956
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Adamas Reagent, Ltd.
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Shanghai Sphchem Co., Ltd.
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Changzhou Joyous Chemical Co., Ltd.
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0519-85607258
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0519-85607278
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sales@joyouschem.com
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China
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Shanghai T&W Pharmaceutical Co., Ltd.
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+86 21 61551611
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Beijing Comparison Pharmaceutical Technology Co., Ltd
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View Lastest Price from 1H-Pyrazolo[3,4-b]pyridine-3-carboximidamide, 1-[(2-fluorophenyl)methyl]-, hydrochloride (1:1) manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide hydrochloride 256499-19-1
Price
US $0.00/g
Min. Order
1g
Purity
98.0%
Supply Ability
10kg/month
Release date
2021-12-17
Xinxiang Hongqi District Houyuan Trading Co.,Ltd
Product
Riociguanidine Intermediate 256499-19-1
Price
US $30.00-28.00/Kg
Min. Order
1Kg
Purity
99.0% up
Supply Ability
50 tons per month
Release date
2022-09-16
Career Henan Chemical Co
Product
1-(2-Fluoro-benzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxaMidine hydrochloride 256499-19-1
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
Customized
Release date
2018-12-17

256499-19-1, 1H-Pyrazolo[3,4-b]pyridine-3-carboximidamide, 1-[(2-fluorophenyl)methyl]-, hydrochloride (1:1)Related Search:

BENZENEAZOMALONONITRILE 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile methyl (4,6-diamino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b] pyridin-3-yl)pyrimidin-5-yl)(ethyl)carbamate 6-amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)- 7,9-dimethyl-7,9-dihydro-8H-purin-8-one 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid 1-(3-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide 6-amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)- 7,9-dihydro-8H-purin-8-one 2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-N5,N5- dimethylpyrimidine-4,5,6-triamine isopropyl(4,6-diamino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b] pyridin-3-yl)pyrimidin-5-yl)(methyl)carbamate 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxaMide 6-amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl) -7-methyl-7,9-dihydro-8H-purin-8-one Riociguat 4,6-PyriMidinediaMine, 2-[1-[(2-fluorophenyl)Methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-(phenylazo)- 2-[1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyriMidine-4,5,6-triaMine Methyl [4,6-diaMino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyriMidin-5-yl]carbaMate

  • 1-(2-Fluoro-benzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxaMidine hydrochloride
  • 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide hydrochloride
  • 1-[(2-Fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide monohydrochloride
  • 1-(2-fluorobenzyl)-1H-pyrazolo 3,4-b pyridine-3-carboxiMidaMide HCL
  • 1-[(2-Fluorophenyl)Methyl]-1h-pyrazolo[3,4-b]pyridine-3-carboxiMidaMide hydrochloride
  • 1-(2-Fluoro-benzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamidine
  • 1-(2-Flurobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-carboxamidine hydrochloride
  • 1H-Pyrazolo[3,4-b]pyridine-3-carboximidamide,1-[(2-fluorophenyl)methyl]-, monohydrochloride
  • 1-(2-FLUORO-BENZYL)-1H-PYRAZOL[3,4-B]PYRIDINE-3-CARBOXAMIDINE HYDROCHLORIDE
  • 1-(2-FLUORO-BENZYL)-1H-PYRAZOLO[3,4-B]PYRIDINE-3-CARBOXAMIDINE HCL
  • Riociguat-10
  • 1-(2-fluorobenzyl)-1H-pyrazolo
  • 1-[(2-FLUOROPHENYL)METHYL]-1H-PYRAZOLO[3,4-B]PYRIDINE-3-CARBOXIMIDAMIDE ONOHYDROCHLORIDE
  • 1H-Pyrazolo[3,4-b]pyridine-3-carboximidamide,1-[(2-fluorophe...
  • Riociguanidine Intermediate
  • 1H-Pyrazolo[3,4-b]pyridine-3-carboximidamide, 1-[(2-fluorophenyl)methyl]-, hydrochloride (1:1)
  • 1-[(2-fluorophenyl)methyl]-1H-Pyrazolo[3,4-b]pyridine-3-carboximidamide hydrochloride (1:1)
  • Riociguat Impurity 3 HCl
  • 1-(2-Fluoro-benzyl)-1H-py...
  • 1- (2-fluorobenzyl) -1H pyrazolo [3,4-B] pyridine-3-formamidine hydrochloride
  • Riociguat EP Impurity 10
  • IH-Pyrazolo[3,4-b]pyridine-3-carboximidamide,1- [(2-fluorophenyl)methyl]-,monohydrochloride
  • Riociguat Impurity 2 HCl
  • 256499-19-1
  • C14H12FN5ClH
  • C14H12FN5HCl
  • C14H13ClFN5