ChemicalBook > CAS DataBase List > Propanoic acid, 2,2-dimethyl-, [[[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]ethoxyphosphinyl]oxy]methyl ester

Propanoic acid, 2,2-dimethyl-, [[[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]ethoxyphosphinyl]oxy]methyl ester

Product Name
Propanoic acid, 2,2-dimethyl-, [[[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]ethoxyphosphinyl]oxy]methyl ester
CAS No.
142341-04-6
Chemical Name
Propanoic acid, 2,2-dimethyl-, [[[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]ethoxyphosphinyl]oxy]methyl ester
Synonyms
Adefovir Impurity E;Mono-POM Ethyl Adefovir;Adefovir Dipivoxil Impurity C;Adefovir Dipivoxyl IMpurity C;Mono(pivaloyloxyMethyl) Ethyl Adefovir;[[[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]ethoxyphosphinyl]oxy]methyl ester;((((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)-(ethoxy)phosphoryl)oxy)methyl pivalate;[2-(6-aminopurin-9-yl)ethoxymethyl-ethoxyphosphoryl]oxymethyl 2,2-dimethylpropanoate;2,2-dimethylpropanoic acid [2-(6-aminopurin-9-yl)ethoxymethyl-ethoxyphosphoryl]oxymethyl ester;Propanoic acid, 2,2-dimethyl-, [[[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]ethoxyphosphinyl]oxy]methy
CBNumber
CB52533914
Molecular Formula
C16H26N5O6P
Formula Weight
415
MOL File
142341-04-6.mol
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Propanoic acid, 2,2-dimethyl-, [[[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]ethoxyphosphinyl]oxy]methyl ester Property

Melting point:
68-70°C
Boiling point:
586.4±60.0 °C(Predicted)
Density 
1.39
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
4.17±0.10(Predicted)
color 
Pale Yellow
Stability:
Moisture Sensitive
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Usbiological
Product number
017828
Product name
Mono-POM Ethyl Adefovir
Packaging
2.5mg
Price
$475
Updated
2021/12/16
Usbiological
Product number
282947
Product name
Mono-POM ethyl adefovir
Packaging
1mg
Price
$475
Updated
2021/12/16
TRC
Product number
M567050
Product name
Mono-POMEthylAdefovir
Packaging
2.5mg
Price
$160
Updated
2021/12/16
Matrix Scientific
Product number
096002
Product name
((((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)-(ethoxy)phosphoryl)oxy)methyl pivalate
Purity
95+%
Packaging
250mg
Price
$265
Updated
2021/12/16
AK Scientific
Product number
6958AA
Product name
((((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)(ethoxy)phosphoryl)oxy)methylpivalate
Packaging
250mg
Price
$407
Updated
2021/12/16
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Propanoic acid, 2,2-dimethyl-, [[[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]ethoxyphosphinyl]oxy]methyl ester Chemical Properties,Usage,Production

Uses

An analogue of the antiviral drug Adefovir (A247500) with a mono-POM ester protecting group.

Propanoic acid, 2,2-dimethyl-, [[[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]ethoxyphosphinyl]oxy]methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Propanoic acid, 2,2-dimethyl-, [[[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]ethoxyphosphinyl]oxy]methyl ester Suppliers

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142341-04-6, Propanoic acid, 2,2-dimethyl-, [[[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]ethoxyphosphinyl]oxy]methyl esterRelated Search:

Adefovir iMpurity [[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]phosphonic acid diethyl ester Adefovir dipivoxyl impuritiesb (adefovir dipivoxyl dimer ) 2-(6-Aminopurin-9-yl)ethanol Diethyl (tosyloxy)methylphosphonate Adefovir dipivoxil (((2-(6-aMino-9H-purin-9-yl)ethoxy)Methyl)phosphoryl)bis(oxy)bis(Methylene) isopropyl dicarbonate Propanoic acid, 2,2-dimethyl-, [[[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]hydroxyphosphinyl]oxy]methyl ester 9-vinyl-9H-purin-6-amine Adefovir ((hydroxy((2-(6-pivalaMido-9H-purin-9-yl)ethoxy)Methyl)phosphoryl)oxy)Methyl pivalate Adefovir Impurity 30 6-(BETA-HYDROXYETHYLAMINO)-PURINE 2,2-Dimethylpropanoic acid 1,1'-[[[[2-[6-[(2,2-dimethyl-1-oxopropyl)amino]-9H-purin-9-yl]ethoxy]methyl]phosphinylidene]bis(oxymethylene)] ester Adefovir Dipivoxil Impurity 20 Ethylene carbonate ADEFOVIR-D4 Adefovir Disoproxil Dimer Impurity

  • Mono(pivaloyloxyMethyl) Ethyl Adefovir
  • Mono-POM Ethyl Adefovir
  • Propanoic acid, 2,2-dimethyl-, [[[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]ethoxyphosphinyl]oxy]methyl ester
  • 2,2-Dimethylpropanoic acid [[[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]ethoxyphosphinyl]oxy]methyl ester
  • [2-(6-aminopurin-9-yl)ethoxymethyl-ethoxyphosphoryl]oxymethyl 2,2-dimethylpropanoate
  • 2,2-dimethylpropanoic acid [2-(6-aminopurin-9-yl)ethoxymethyl-ethoxyphosphoryl]oxymethyl ester
  • Adefovir Dipivoxyl IMpurity C
  • Propanoic acid, 2,2-dimethyl-, [[[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]ethoxyphosphinyl]oxy]methy
  • Adefovir Dipivoxil Impurity C
  • [[[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]ethoxyphosphinyl]oxy]methyl ester
  • Adefovir Impurity E
  • ((((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)-(ethoxy)phosphoryl)oxy)methyl pivalate
  • 142341-04-6
  • C16H26N5O6P
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  • Pharmaceuticals