ChemicalBook > CAS DataBase List > 5-Chloro-3-(trifluoromethyl)-2-pyridinamine

5-Chloro-3-(trifluoromethyl)-2-pyridinamine

Product Name
5-Chloro-3-(trifluoromethyl)-2-pyridinamine
CAS No.
79456-33-0
Chemical Name
5-Chloro-3-(trifluoromethyl)-2-pyridinamine
Synonyms
5-Chloro-3-(trifluoroMethyl)pyridin-2-aMine;5-Chloro-3-(trifluoromethyl)-2-pyridinamine;5-Chloro-3-trifluoroMethyl-pyridin-2-ylaMine;2-Pyridinamine, 5-chloro-3-(trifluoromethyl)-
CBNumber
CB52534597
Molecular Formula
C6H4ClF3N2
Formula Weight
196.56
MOL File
79456-33-0.mol
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5-Chloro-3-(trifluoromethyl)-2-pyridinamine Property

Boiling point:
218℃
Density 
1.507
Flash point:
85℃
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
1.95±0.49(Predicted)
Appearance
Off-white to light yellow Solid
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
C381943
Product name
5-Chloro-3-(trifluoromethyl)pyridin-2-amine
Packaging
500mg
Price
$155
Updated
2021/12/16
Apolloscientific
Product number
PC201309
Product name
5-Chloro-3-(trifluoromethyl)pyridin-2-amine
Purity
95+%
Packaging
1g
Price
$60
Updated
2021/12/16
SynQuest Laboratories
Product number
3H30-7-1E
Product name
5-Chloro-3-(trifluoromethyl)pyridin-2-amine
Purity
95.0%
Packaging
1g
Price
$96
Updated
2021/12/16
AK Scientific
Product number
Z5142
Product name
5-Chloro-3-(trifluoromethyl)pyridin-2-amine
Packaging
5g
Price
$271
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0367259
Product name
5-CHLORO-3-(TRIFLUOROMETHYL)PYRIDIN-2-AMINE
Purity
95.00%
Packaging
5MG
Price
$495.65
Updated
2021/12/16
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5-Chloro-3-(trifluoromethyl)-2-pyridinamine Chemical Properties,Usage,Production

Synthesis

183610-70-0

79456-33-0

General procedure for the synthesis of 5-chloro-3-(trifluoromethyl)pyridin-2-amines from 2-amino-3-trifluoromethylpyridine: Step A Synthesis of 5-chloro-3-(trifluoromethyl)-2-pyridinamine [0120] To a solution of N,N-dimethylformamide (100 mL) containing 3-(trifluoromethyl)-2-pyridinamine (12.2 g, 75 mmol), N-chlorosuccinimide (10.5 g, 79 mmol) was added. The reaction mixture was heated to 60 °C and stirred continuously for 1 hour. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently concentrated. The residue was purified by silica gel column chromatography using dichloromethane as eluent to give 5-chloro-3-(trifluoromethyl)pyridin-2-amine (13.0 g, 88% yield). m/z 197 (M + 1) by LCMS.

References

[1] Patent: WO2010/91411, 2010, A1. Location in patent: Page/Page column 88-89
[2] Patent: WO2011/41713, 2011, A2. Location in patent: Page/Page column 206
[3] Patent: WO2015/79224, 2015, A1. Location in patent: Page/Page column 60; 61

5-Chloro-3-(trifluoromethyl)-2-pyridinamine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 5-Chloro-3-(trifluoromethyl)-2-pyridinamine manufacturers

Career Henan Chemical Co
Product
5-Chloro-3-(trifluoromethyl)pyridin-2-amine 79456-33-0
Price
US $1.00/g
Min. Order
1g
Purity
95--99%
Supply Ability
1ton
Release date
2020-01-09

79456-33-0, 5-Chloro-3-(trifluoromethyl)-2-pyridinamineRelated Search:

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  • 5-Chloro-3-(trifluoromethyl)-2-pyridinamine
  • 5-Chloro-3-(trifluoroMethyl)pyridin-2-aMine
  • 5-Chloro-3-trifluoroMethyl-pyridin-2-ylaMine
  • 2-Pyridinamine, 5-chloro-3-(trifluoromethyl)-
  • 79456-33-0