3-O-trans-p-CouMaroyltorMentic acid
- Product Name
- 3-O-trans-p-CouMaroyltorMentic acid
- CAS No.
- 121064-78-6
- Chemical Name
- 3-O-trans-p-CouMaroyltorMentic acid
- Synonyms
- 3-O-p-CouMaroyltorMentic acid;3-O-trans-p-Coumaroyltormenticaci;3-O-trans-p-CouMaroyltorMentic acid;Urs-12-en-28-oic acid, 2,19-dihydroxy-3-[[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]oxy]-, (2α,3β)-
- CBNumber
- CB52566525
- Molecular Formula
- C39H54O7
- Formula Weight
- 634.85
- MOL File
- 121064-78-6.mol
3-O-trans-p-CouMaroyltorMentic acid Property
- Melting point:
- 245-247 °C(Solv: methanol (67-56-1))
- Boiling point:
- 745.5±60.0 °C(Predicted)
- Density
- 1.23±0.1 g/cm3(Predicted)
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
- pka
- 4.45±0.70(Predicted)
N-Bromosuccinimide Price
- Product number
- PXT0003546
- Product name
- 3-O-TRANS-PARA-COUMAROYLTORMENTIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.58
- Updated
- 2021/12/16
- Product number
- CFN97843
- Product name
- 3-O-trans-p-Coumaroyltormenticacid
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $593
- Updated
- 2021/12/16
- Product number
- CD32002705
- Product name
- 3-O-p-Coumaroyltormenticacid
- Purity
- 95+%
- Packaging
- 5mg
- Price
- $922
- Updated
- 2021/12/16
3-O-trans-p-CouMaroyltorMentic acid Chemical Properties,Usage,Production
Description
3-O-(E)-p-coumaroyl tormentic acid induces apoptotic cell death in human leukemia (HL60) via mainly mitochondrial pathway by, at least in part, Topo I inhibition, it may be promising lead compound for developing an effective drug for treatment of leukemia. 3-O-trans-p-coumaroyltormentic acid shows cytotoxicity against four human tumor cell lines (A549, SK-OV-3, SK-MEL-2, and HCT-15) in vitro, the IC50 values of 13.72, 14.29,14.61, 14.04 uM, respectively. 3. 3beta-O-cis-p-Coumaroyltormentic acid, and 3beta-O-trans-p-coumaroyltormentic acid are weakly selective for vancomycin-resistant Enterococcus (VRE) compared with eukaryotic cells, with an MIC of 59.4microg/mL and a 50% inhibitory concentration (IC50) of 70microg/mL for monkey kidney epithelial (MA104) cells. 4. A mixture of 3-O-cis-p-coumaroyltormentic acid and 3-O-trans-p-coumaroyltormentic acid shows an inhibitory effect comparable to (-)-epigallocatechin gallate (EGCG) of green tea on the activation of Epstein-Barr virus early antigen (EBV-EA) induced by 12-O-tetradeca--noylphorbol-13-acetate (TPA).
Definition
ChEBI: 3-O-trans-p-coumaroyltormentic acid is a triterpenoid. It has a role as a metabolite.
target
Antifection | Caspase
3-O-trans-p-CouMaroyltorMentic acid Preparation Products And Raw materials
Raw materials
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