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5(6)-Carboxyfluorescein

Product Name
5(6)-Carboxyfluorescein
CAS No.
72088-94-9
Chemical Name
5(6)-Carboxyfluorescein
Synonyms
5(6)-FAM;DCFA;5(6)-Carboxyfluoresc;5(6)-CARBOXYLUORESCEIN;4(5)-CARBOXYFLUORESCEIN;5(6)-CARBOXYFLUORESCEIN;5(6)-Carboxyfluoresceine];4(5)-Carboxyfluoresceine];Fluoresceincarboxylic Acid;5(6)-CARBOXYFLUORESCEIN 99%
CBNumber
CB5257173
Molecular Formula
C42H24O14
Formula Weight
752.63
MOL File
72088-94-9.mol
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5(6)-Carboxyfluorescein Property

Melting point:
275 °C
Boiling point:
464.9°C (rough estimate)
Density 
1.3418 (rough estimate)
refractive index 
1.6380 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO (Sparingly), Methanol (Slightly, Heated)
form 
Solid
color 
Light Yellow to Dark Brown
Water Solubility 
slightly soluble
InChIKey
CPRVUBZYHZGASQ-UHFFFAOYSA-N
SMILES
C12(OC(=O)C3C=CC(C(=O)O)=CC1=3)C1=CC=C(O)C=C1OC1C=C(O)C=CC2=1.C12(OC(=O)C3C=C(C(=O)O)C=CC1=3)C1=CC=C(O)C=C1OC1C=C(O)C=CC2=1
EPA Substance Registry System
Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-ar-carboxylic acid, 3',6'-dihydroxy-3-oxo- (72088-94-9)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36-36/37/38-20/21/22
Safety Statements 
37/39-26-36-22
WGK Germany 
3
TSCA 
Yes
HS Code 
29322090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.51082
Product name
5(6)-Carboxyfluorescein
Purity
Novabiochem?
Packaging
1g
Price
$58
Updated
2024/03/01
Sigma-Aldrich
Product number
8.51082
Product name
5(6)-Carboxyfluorescein
Purity
Novabiochem?
Packaging
5G
Price
$194
Updated
2024/03/01
Sigma-Aldrich
Product number
21877
Product name
5(6)-Carboxyfluorescein
Purity
BioReagent, suitable for fluorescence, ≥95% (HPLC)
Packaging
1g
Price
$60.9
Updated
2024/03/01
Sigma-Aldrich
Product number
21877
Product name
5(6)-Carboxyfluorescein
Purity
BioReagent, suitable for fluorescence, ≥95% (HPLC)
Packaging
5G
Price
$207
Updated
2024/03/01
Alfa Aesar
Product number
L13439
Product name
5(6)-Carboxyfluorescein, mixture of isomers, 97%
Packaging
250mg
Price
$51.65
Updated
2024/03/01
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5(6)-Carboxyfluorescein Chemical Properties,Usage,Production

Description

5(6)-Carboxyfluorescein is a mixture of 5-carboxy and 6-carboxy derivatives of fluorescein. It is commonly used to label biomolecules through a reaction involving the carboxyl group. Unlike its succinimidyl ester derivative CFSE , 5(6)-carboxyfluorescein is membrane impermeant. As a result, it can be used in studies of membrane permeability. 5(6)-Carboxyfluorescein displays excellent fluorescence (excitation/emission at 492/514 nm, respectively), and its excitation maximum closely matches the 488 nm spectral line of argon-ion lasers.

Chemical Properties

Dark-Orange to Brown Solid

Uses

A popular probe of determination of intracellular pH.

Uses

5(6)-FAM, A useful reagent for the preparation of hydrolytically stable fluorescent conjugates and is a useful starting material for the synthesis of other fluorescein-derives reagent.

Uses

As a popular probe of determination of intracellular pH, 5(6)-Carboxyfluoresceincan be used as useful reagent for the preparation of hydrolytically stable fluorescent conjugates and a useful starting material for the synthesis of other fluorescein-derives reagent

Definition

ChEBI: 5(6)-carboxyfluorescein is a commercially available mixture of 5-carboxyfluorescein and 6-carboxyfluorescein isomers. A fluorescent dye, it is commonly used as a tracer agent. It has a role as a tracer and a fluorescent dye. It contains a 5-carboxyfluorescein and a 6-carboxyfluorescein.

Solubility in organics

5(6)-Carboxyfluorescein is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide. The solubility of 5(6)-carboxyfluorescein in these solvents is approximately 5, 0.5, and 1 mg/ml, respectively.

5(6)-Carboxyfluorescein Preparation Products And Raw materials

Raw materials

Preparation Products

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5(6)-Carboxyfluorescein Suppliers

Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
India
ProdList
6905
Advantage
58
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
CHEMSWORTH
Tel
--
Fax
--
Email
info@chemsworth.com
Country
India
ProdList
6700
Advantage
30
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View Lastest Price from 5(6)-Carboxyfluorescein manufacturers

hebei hongtan Biotechnology Co., Ltd
Product
5(6)-Carboxyfluorescein 72088-94-9
Price
US $30.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
3000kg
Release date
2024-03-22
Hebei Weibang Biotechnology Co., Ltd
Product
5(6)-Carboxyfluorescein 72088-94-9
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-28
Hebei Yanxi Chemical Co., Ltd.
Product
5(6)-Carboxyfluorescein 72088-94-9
Price
US $40.00-15.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10 tons
Release date
2023-09-12

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