2-Acetylthiophene
Description- Product Name
- 2-Acetylthiophene
- CAS No.
- 88-15-3
- Chemical Name
- 2-Acetylthiophene
- Synonyms
- Ethanone, 1-(2-thienyl)-;AKOS 91936;2-Acetylthioph;2-Acetothienone;2-Acetylthiophen;2-ACETYLTHIOLE;2-ACETOTHIOPHENE;-Acetylthiophene;2-ACETYLTHIOPHENE;AKOS BBS-00000940
- CBNumber
- CB5259889
- Molecular Formula
- C6H6OS
- Formula Weight
- 126.18
- MOL File
- 88-15-3.mol
2-Acetylthiophene Property
- Melting point:
- 10-11 °C (lit.)
- Boiling point:
- 214 °C (lit.)
- Density
- 1.168 g/mL at 25 °C (lit.)
- vapor pressure
- 2.7 hPa (50 °C)
- refractive index
- n20/D 1.565(lit.)
- Flash point:
- 196 °F
- storage temp.
- Store below +30°C.
- solubility
- 14g/l
- form
- Liquid
- color
- Clear pale yellow to light brown
- Odor
- at 100.00 %. sulfurous nutty hazelnut walnut
- Odor Type
- sulfurous
- Water Solubility
- Insoluble in water.
- Sensitive
- Light Sensitive
- BRN
- 107910
- InChIKey
- WYJOVVXUZNRJQY-UHFFFAOYSA-N
- LogP
- 1.250
- CAS DataBase Reference
- 88-15-3(CAS DataBase Reference)
- NIST Chemistry Reference
- Ethanone, 1-(2-thienyl)-(88-15-3)
- EPA Substance Registry System
- Ethanone, 1-(2-thienyl)- (88-15-3)
Safety
- Hazard Codes
- T,Xi,Xn
- Risk Statements
- 25-23/24/25-20/21/22
- Safety Statements
- 45-38-36/37/39-28-36
- RIDADR
- UN 2810 6.1/PG 2
- WGK Germany
- 3
- RTECS
- OB6300000
- F
- 13
- Autoignition Temperature
- 265 °C DIN 51794
- Hazard Note
- Irritant
- TSCA
- Yes
- HazardClass
- 6.1
- PackingGroup
- II
- HS Code
- 29349990
- Toxicity
- LD50 orally in Rabbit: 25 - 200 mg/kg LD50 dermal Rat 370 mg/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H311Toxic in contact with skin
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- A22602
- Product name
- 2-Acetylthiophene
- Purity
- 98%
- Packaging
- 25g
- Price
- $38
- Updated
- 2023/06/20
- Product number
- W503509
- Product name
- 2-Acetylthiophene
- Purity
- ≥98%, FG
- Packaging
- 250g
- Price
- $173
- Updated
- 2023/06/20
- Product number
- W503509
- Product name
- 2-Acetylthiophene
- Purity
- ≥98%, FG
- Packaging
- 1kg
- Price
- $521
- Updated
- 2023/01/07
- Product number
- 8.00175
- Product name
- 2-Acetylthiophene
- Purity
- for synthesis
- Packaging
- 50mL
- Price
- $110
- Updated
- 2023/01/07
- Product number
- 8.00175
- Product name
- 2-Acetylthiophene
- Purity
- for synthesis
- Packaging
- 250ML
- Price
- $450
- Updated
- 2023/01/07
2-Acetylthiophene Chemical Properties,Usage,Production
Description
2-Acetylthiophene occurs naturally in kohlrabi. It has a sulfurous nutty hazelnut odor. It can be used as a food additive. It is also used as an intermediate to produce drugs, such as Tiamonium Iodide, Suprofan, Stepronin, Tenonitrozole, Namirotene, etc.
Chemical Properties
clear colorless to slightly yellow liquid
Uses
2-Acetylthiophene(2AT) is used as an intermediate in the manufacturing of drugs like Tiamonium Iodide, Suprofan, Stepronin, Tenonitrozole, Namirotene, etc. 2AT is used as an important precursor to thiophene-2-acetic acid (T2AA) or its acid chloride (Cl) and thiophene-2-carboxylic acid (T2CA) (Cl). It is important that the process used to synthesize 2AT yields the lowest amount of 3- acetylthiophene isomer.
Definition
ChEBI: 2-Acetylthiophene is an aromatic ketone.
Synthesis Reference(s)
Organic Syntheses, Coll. Vol. 2, p. 8, 1943
The Journal of Organic Chemistry, 36, p. 540, 1971 DOI: 10.1021/jo00803a011
Tetrahedron Letters, 40, p. 3109, 1999 DOI: 10.1016/S0040-4039(99)00476-1
Safety Profile
Poison by intraperitoneal route. A flammable liquid. When heated to decomposition emits toxic fumes of SOx,.
Purification Methods
Fractionally distil the thiophene through a 12-plate column, and fraction b 77o/4mm is collected. Also wet the acetylthiophene in order to remove and free thiophene which forms an azeotrope with H2O, b 68o. Store it in a brown bottle, and the clear colourless liquid remains thus for extended periods. [Kosak & Hartough Org Synth Coll Vol III 14 1955, Hartough & Kosak J Am Chem Soc 69 3093 1947.] The red 4-nitrophenylhydrazone crystallises from EtOH with m 181-182o. [Beilstein 17/9 V 387.]
2-Acetylthiophene Preparation Products And Raw materials
Raw materials
Preparation Products
2-Acetylthiophene Suppliers
- Tel
- 0728-3264711 18672872888
- 724732323@qq.com
- Country
- China
- ProdList
- 1
- Advantage
- 58
- Tel
- 0536-8888106 17663601818
- Fax
- 0536-8888106
- 2354379876@qq.com
- Country
- China
- ProdList
- 246
- Advantage
- 58
- Tel
- 027-59223025 15107168801
- Fax
- 027-59223025
- 1718480011@qq.com
- Country
- China
- ProdList
- 9855
- Advantage
- 58
- Tel
- 023-55703781 15320534687
- Fax
- 023-55703781
- 2022434087@qq.com
- Country
- China
- ProdList
- 4100
- Advantage
- 58
- Tel
- 13506120961
- 1871415438@163.com
- Country
- China
- ProdList
- 25
- Advantage
- 58
- Tel
- 010-82848833 400-666-7788
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 021-61259108 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 400-0066400 13621662912
- Fax
- 021-55660885
- sales@jonln.com
- Country
- China
- ProdList
- 1995
- Advantage
- 65
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- +86 351 7031519
- Fax
- +86 351 7031519
- sales@RHFChem.com
- Country
- China
- ProdList
- 2338
- Advantage
- 56
View Lastest Price from 2-Acetylthiophene manufacturers
- Product
- 2-ACETYLTHIOPHENE 88-15-3
- Price
- US $1.00/PCS
- Min. Order
- 1PCS
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-10-30
- Product
- 2-Acetylthiophene 88-15-3
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-30
- Product
- 2-Acetylthiophene 88-15-3
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20tons
- Release date
- 2023-09-11