4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline

Product Name: 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline
CAS No.: 190728-25-7
Chemical Name: 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline
Synonyms: Benzenam;4-(6,7-Dimethoxy-quinoL;Cabozantinib Amine Analog;Intermediate 1 of Cabozantinib;Cabozantinib Genotoxic Impurity I;4-[(6,7-dimethoxy-4-quinolinyl)oxy]-;4-(6,7-dimethoxy quinolinoxy) aniline;4-[(6,7-Dimethoxy-4-quinolyl)oxy]aniline;6,7-Dimethoxy-4-(4-aminophenoxy)quinoline;4-(4-Aminophenoxy)-6,7-dimethoxyquinoline
CBNumber: CB52652846
Molecular Formula: C17H16N2O3
Formula Weight: 296.32
MOL File: 190728-25-7.mol

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4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline Property

Melting point:: 211.0 to 215.0 °C
Boiling point:: 481.8±45.0 °C(Predicted)
Density: 1.246±0.06 g/cm3 (20 ºC 760 Torr)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: DMSO (Slightly, Sonicated), Methanol (Slightly)
form: powder to crystal
pka: 6.79±0.30(Predicted)
color: Light yellow to Brown
InChI: InChI=1S/C17H16N2O3/c1-20-16-9-13-14(10-17(16)21-2)19-8-7-15(13)22-12-5-3-11(18)4-6-12/h3-10H,18H2,1-2H3
InChIKey: VXEQRXJATQUJSN-UHFFFAOYSA-N
SMILES: C1(N)=CC=C(OC2C3C(N=CC=2)=CC(OC)=C(OC)C=3)C=C1

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Safety

HS Code: 2933.49.7000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical

Product number: D5070
Product name: 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline
Packaging: 200mg
Price: $155
Updated: 2024/03/01

TCI Chemical

Product number: D5070
Product name: 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline
Packaging: 1g
Price: $460
Updated: 2024/03/01

Chem-Impex

Product number: 43936
Product name: 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline,≥98%(HPLC)
Purity: ≥98%(HPLC)
Packaging: 1G
Price: $540.8
Updated: 2021/12/16

AK Scientific

Product number: J90694
Product name: 4-(6,7-Dimethoxy-quinolin-4-yloxy)-phenylamine
Packaging: 1g
Price: $20
Updated: 2021/12/16

Ambeed

Product number: A138452
Product name: 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline
Purity: 97%
Packaging: 5g
Price: $54
Updated: 2021/12/16

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4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline Chemical Properties,Usage,Production

Uses

4-(6,7-Dimethoxy-Quinolin-4-Yloxy)-Phenylamine is used in preparation of Cabozantinib Defluorination impurity.

Chemical Reactivity

4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline is a primary alcohol that has been shown to catalyze the reaction of potassium carbonate with an alkali metal hydroxide to produce potassium. It has also been shown to be a base catalyst for the reaction of cyclopropanecarboxylic acid with an alcohol ester to produce high yield.

4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline Preparation Products And Raw materials

Raw materials

Preparation Products

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4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline Suppliers

Americas 1 China 182 Europe 1 India 9 Japan 1 United States 10 Global 204

Shanghai Yuzhicheng Pharmaceutical Technology Co., Ltd.

Tel: 18001856580
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Shandong Xuande Pharmaceutical Technology Co. LTD

Tel: 18866895588
Fax: 0531-82777287
Email: dingjiaying@shiningpharm.com
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shanghai huiyu

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Tianjin Branch Chong pharmaceutical intermediates Co., Ltd.

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Chongqing Longsheng Pharmaceutical Co., Ltd

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TIANJIN PHARMACN MEDICAL TECHNOLOGY CO.,LTD.

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Adamas Reagent, Ltd.

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Shanghai Hanhong Scientific Co.,Ltd.

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Shanghai XueEr Pharmaceutical Technology Co., Ltd

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View Lastest Price from 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline manufacturers

Nanjing Fred Technology Co., Ltd

Product: 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline 190728-25-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1 ton
Release date: 2023-12-26

Henan Fengda Chemical Co., Ltd

Product: 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline 190728-25-7
Price: US $200.00-1.00/KG
Min. Order: 1KG
Purity: 99%, 99.5% Sublimated
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-30

LY Global chemicals co.,ltd .

Product: BenzenaMine, 4-[(6,7-diMethoxy-4-quinolinyl)oxy]- 190728-25-7
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98.0%min
Supply Ability: 100kg
Release date: 2023-03-11

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CAS 190728-25-7 BenzenaMine, 4-[(6,7-diMethoxy-4-quinolinyl)oxy]-

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