ChemicalBook > CAS DataBase List > Liquiritin apioside
Liquiritin apioside
- Product Name
- Liquiritin apioside
- CAS No.
- 74639-14-8
- Chemical Name
- Liquiritin apioside
- Synonyms
- Liquiritin apioside-RM;Liquiritin apioside, 10 mM in DMSO;4H-1-Benzopyran-4-one, 2-[4-[(2-O-D-apio-β-D-furanosyl-β-D-glucopyranosyl)oxy]phenyl]-2,3-dihydro-7-hydroxy-, (2S)-;(2S)-2-[4-[(2S,3R,4S,5S,6R)-3-[(2S,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-7-hydroxy-2,3-dihydrochromen-4-one
- CBNumber
- CB52654123
- Molecular Formula
- C26H30O13
- Formula Weight
- 550.51
- MOL File
- 74639-14-8.mol
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Liquiritin apioside Property
- Boiling point:
- 904.5±65.0 °C(Predicted)
- Density
- 1.65±0.1 g/cm3 (20 ºC 760 Torr)
- form
- Solid
- pka
- 7.70±0.40(Predicted)
- color
- White to light yellow
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- PHL84233
- Product name
- Liquiritin apioside
- Purity
- phyproof? Reference Substance
- Packaging
- 10MG
- Price
- $495
- Updated
- 2025/07/31
TRC
- Product number
- L468835
- Product name
- LiquiritinApioside
- Packaging
- 2.5mg
- Price
- $120
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FL71832
- Product name
- Liquiritin apioside
- Packaging
- 5mg
- Price
- $138
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FL71832
- Product name
- Liquiritin apioside
- Packaging
- 10mg
- Price
- $240
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FL71832
- Product name
- Liquiritin apioside
- Packaging
- 2mg
- Price
- $69
- Updated
- 2021/12/16
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Liquiritin apioside Chemical Properties,Usage,Production
Uses
Liquiritin Apioside is one of the main active components in Suan-Zao-Ren decoction as a treatment for insomnia.
Definition
ChEBI: Liquiritin apioside is a member of flavonoids and a glycoside.
in vivo
Liquiritin apioside (10 μg/μL, intralaryngeal or perineural administration; single dose; 10 min, 20 min) significantly attenuates the apnea, hypertension, and bradycardia responses to the laryngeal chemoreflex (LCR) induced by Capsaicin (HY-10448), hydrochloric acid (HCl), and distilled water (DW) in rat pups, but has no significant effect on the laryngeal mechanoreflex (LMR) induced by air pulse (AP) [1].
Liquiritin apioside (0.01 g/kg, 0.2 g/kg; po; once daily for 10 days) ameliorates DSS-induced colitis in mice, and modulates the gut microbial diversity and composition[2].
| Animal Model: | Laryngeal reflexe study in Sprague-Dawley rat (250-350 g) pups[1] |
| Dosage: | 10 μg/μL (diluted in saline) |
| Administration: | Intralaryngeal perfusion for 10 minutes or peri-treatment for 20 minutes, single dose |
| Result: | Significantly reduced the apneic responses to CAP, HCl, and DW, as well as attenuated the hypertension and bradycardia responses to these stimuli. Did not change the cardiorespiratory responses to AP. Peri-SLN treatment with Liquiritin apioside also suppressed the apnea, hypertension, and bradycardia responses to CAP, HCl, and DW, similar to the effect of intralaryngeal treatment. |
| Animal Model: | DSS-induced colitis model in C57BL/6 mice (male, 18–22 g, 8–10 weeks)[2] |
| Dosage: | 0.01 g/kg, 0.02 g/kg (diluted in saline) |
| Administration: | Oral gavaged for 10 days, once daily |
| Result: | Exhibited the same pathological changes as that of the ABX (DSS) group mice, specifically, comparable weight loss, DAI score, colon length, and histology score. |
Liquiritin apioside Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Liquiritin apioside manufacturers
Nanjing Sky Hope Tongyuan Biological Engineering Co., Ltd.
- Product
- apioside 74639-14-8
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100kg
- Release date
- 2021-07-28
Shanghai Standard Technology Co., Ltd.
- Product
- Liquiritin apioside 74639-14-8
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2019-11-07
Career Henan Chemical Co
- Product
- Liquiritin apioside 74639-14-8
- Price
- US $9.80/KG
- Min. Order
- 1KG
- Purity
- ≥98%
- Supply Ability
- 20 tons
- Release date
- 2020-01-09
74639-14-8, Liquiritin apiosideRelated Search:
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