ChemicalBook > CAS DataBase List > Kushenol L

Kushenol L

Product Name
Kushenol L
CAS No.
101236-50-4
Chemical Name
Kushenol L
Synonyms
Kushenol L;product/154902;(2R,3R)-2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-6,8-bis(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one;4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-6,8-bis(3-methyl-2-buten-1-yl)-, (2R,3R)-
CBNumber
CB52654633
Molecular Formula
C25H28O7
Formula Weight
440.49
MOL File
101236-50-4.mol
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Kushenol L Property

Boiling point:
715.7±60.0 °C(Predicted)
Density 
1.334±0.06 g/cm3(Predicted)
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Cryst.
pka
8.04±0.60(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

JR MediChem
Product number
JR8-N1217
Product name
KushenolL
Purity
98%(HPLC)
Packaging
5mg
Price
$518
Updated
2021/12/16
Arctom
Product number
CFN92344
Product name
KushenolL
Packaging
5mg
Price
$553
Updated
2021/12/16
Crysdot
Product number
CD32002987
Product name
KushenolL
Purity
95+%
Packaging
5mg
Price
$860
Updated
2021/12/16
JR MediChem
Product number
JR8-N1217
Product name
KushenolL
Purity
98%(HPLC)
Packaging
10mg
Price
$968
Updated
2021/12/16
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Kushenol L Chemical Properties,Usage,Production

Uses

Kushenol L is one of the main components of EtOA cextracts from Kushen, a traditional medicinal herb derived from the dried roots of Sophora flavescens Ait. Kushenol L is a flavonoid and plays an important role in anti-diabeticeffects[1].

in vivo

Kushenol L (1 mg/kg; oral) has a T1/2 of 2.26 hours, a Cmax of 24.17 μg/L and an AUC of 54035 μg/h?L in adult male Sprague-Dawley rats weighing 300 g[1].

References

[1] Lei Chen, et al. An accurate and reproducible method for simultaneous determination of four flavonoids in EtOAc extracts from Sophora flavescens Ait. in rat plasma based on UHPLC Q-Exactive Mass spectrometry: Application to a pharmacokinetics study. Biomed Chromatogr. 2019 Mar;33(3):e4447. DOI:10.1002/bmc.4447

Kushenol L Preparation Products And Raw materials

Raw materials

Preparation Products

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101236-50-4, Kushenol LRelated Search:


  • Kushenol L
  • product/154902
  • 4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-6,8-bis(3-methyl-2-buten-1-yl)-, (2R,3R)-
  • (2R,3R)-2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-6,8-bis(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one
  • 101236-50-4