ChemicalBook > CAS DataBase List > 5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one

5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one

Product Name
5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one
CAS No.
947502-66-1
Chemical Name
5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one
Synonyms
Prasugrel Hydroxy Thiolactone;Prasugrel impurity F;Prasugrel EP Impurity F;Prasugrel impurities1182;Desacetyl hydroxyprasugrel;Prasugrel Hydroxy Thiolactone Desacetyl hydroxyprasugrel;5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-7a-hydroxy-6,7-dihydro-4H-thieno[3,2-c]pyridin-2-one;5-(2-CYCLOPROPYL-1-(2-FLUOROPHENYL)-2-OXOETHYL)-5,6,7,7A-TETRAHYDRO-7A-HYDROXYTHIENO[3,2-C]PYRIDIN-2(4H)-ONE;5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one;Thieno[3,2-c]pyridin-2(4H)-one, 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-5,6,7,7a-tetrahydro-7a-hydroxy-
CBNumber
CB52655382
Molecular Formula
C18H18FNO3S
Formula Weight
347.4
MOL File
947502-66-1.mol
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5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one Property

Melting point:
>45°C (dec.)
Boiling point:
547.8±50.0 °C(Predicted)
Density 
1.43±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Acetone (Slightly), DMSO (Slightly), Methanol (Slightly)
pka
10.71±0.20(Predicted)
form 
Solid
color 
Off-White to Pale Yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H225Highly Flammable liquid and vapour

H314Causes severe skin burns and eye damage

Precautionary statements

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P330Rinse mouth.

P331Do NOT induce vomiting.

P363Wash contaminated clothing before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

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N-Bromosuccinimide Price

TRC
Product number
P701160
Product name
PrasugrelHydroxyThiolactone
Packaging
5mg
Price
$670
Updated
2021/12/16
Chemenu
Product number
CM175511
Product name
5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one
Purity
97%
Packaging
10mg
Price
$935
Updated
2021/12/16
Crysdot
Product number
CD11005960
Product name
5-(2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one
Purity
97%
Packaging
10mg
Price
$992
Updated
2021/12/16
Crysdot
Product number
CD11005960
Product name
5-(2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one
Purity
97%
Packaging
25mg
Price
$1984
Updated
2021/12/16
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5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one Chemical Properties,Usage,Production

Uses

Prasugrel Hydroxy Thiolactone, is the metabolite of Prasugrel (P701150), which is a novel thienopyridine. It is also a potent inhibitor of platelet aggregation in vivo.

5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

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5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one Suppliers

China 31 India 5 United States 4 Global 40
Standardpharm Co. Ltd.
Tel
86-714-3992388
Email
overseasales1@yongstandards.com
Country
United States
ProdList
14336
Advantage
58
BOC Sciences
Tel
+1-631-485-4226
Fax
1-631-614-7828
Email
inquiry@bocsci.com
Country
United States
ProdList
19553
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58
Cato Research Chemicals Inc.
Tel
020-81215950 4000-868-328
Email
customer@uwalab.com
Country
United States
ProdList
10413
Advantage
58

947502-66-1, 5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-oneRelated Search:

Prasugrel IMpurity (1-BroMo-5-chloro-1-(2-fluorophenyl)pentan-2-one) YXSRVOWUJUXDLJ-UHFFFAOYSA-N 1,2-Dihydro-4,6-diMethyl-2-thioxo-3-pyridinecarboxaMide Cyclopropyl 2-fluorobenzyl ketone 5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochloride Prasugrel alpha-Hydroxy IMpurity trans-R-138727 5-(5-chloro-1-(2-fluorophenyl)-2-oxopentyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate 5-(2-cyclopropyl-1-(4-fluorophenyl) -2-oxoethyl)-4,5,6,7-tetrahydrothieno [3,2-c]pyridin-2-yl acetate 5-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2(3H)-one 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone Mesna Methyl Ester 2-Bromo Analog DTGLZDAWLRGWQN-GEXSZOTCSA-N Prasugrel Metabolite M5 PRASUGREL METABOLITE R-138727 IZCHRAOWOKMDHU-UHFFFAOYSA-N Cyclopropyl 4-Fluorobenzyl Ketone 2-BroMo-1-cyclopropyl-2-(3-fluorophenyl)ethanone

  • 5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one
  • Prasugrel Hydroxy Thiolactone
  • Prasugrel impurity F
  • 5-(2-CYCLOPROPYL-1-(2-FLUOROPHENYL)-2-OXOETHYL)-5,6,7,7A-TETRAHYDRO-7A-HYDROXYTHIENO[3,2-C]PYRIDIN-2(4H)-ONE
  • 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-7a-hydroxy-6,7-dihydro-4H-thieno[3,2-c]pyridin-2-one
  • Prasugrel impurity 5/Prasugrel Hydroxy Thiolactone/5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one
  • Desacetyl hydroxyprasugrel
  • Prasugrel EP Impurity F
  • Thieno[3,2-c]pyridin-2(4H)-one, 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-5,6,7,7a-tetrahydro-7a-hydroxy-
  • Prasugrel impurities1182
  • Prasugrel Hydroxy Thiolactone Desacetyl hydroxyprasugrel
  • 947502-66-1