LY-2584702 (tosylate salt)
- Product Name
- LY-2584702 (tosylate salt)
- CAS No.
- 1082949-68-5
- Chemical Name
- LY-2584702 (tosylate salt)
- Synonyms
- LYS6K2;CS-2145;LY2584702 Tosylate;LY-2584702 (tosylate salt);LY-2584702;LY 2584702;LYS6K2;LY2584702 Tosylate (LYS-6K2);LYS6K2(LY2584702) tosylate salt;LY-2584702 (tosylate salt) USP/EP/BP;LY-2584702 tosylate salt, 10 mM in DMSO;4-{4-[4-(4-fluoro-3-trifluoromethyl-phenyl)-1-methyl-1H-imidazol-2-yl]-piperidin-1-yl}-1H-pyrazolo[3,4-d]pyrimidine p-toluenesulfonate
- CBNumber
- CB52735527
- Molecular Formula
- C28H27F4N7O3S
- Formula Weight
- 617.62
- MOL File
- 1082949-68-5.mol
LY-2584702 (tosylate salt) Property
- storage temp.
- Store at -20°C
- solubility
- DMSO:12.55(Max Conc. mg/mL);20.31(Max Conc. mM)
- form
- A crystalline solid
- color
- Light yellow to yellow
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P273Avoid release to the environment.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P391Collect spillage. Hazardous to the aquatic environment
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- SRP0703
- Product name
- LYS6K2
- Purity
- recombinant
- Packaging
- 25MG
- Price
- $511
- Updated
- 2024/03/01
- Product number
- 15320
- Product name
- LY2584702 (tosylate)
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 15320
- Product name
- LY2584702 (tosylate)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $100
- Updated
- 2024/03/01
- Product number
- 15320
- Product name
- LY2584702 (tosylate)
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $184
- Updated
- 2024/03/01
- Product number
- 15320
- Product name
- LY2584702 (tosylate)
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $420
- Updated
- 2024/03/01
LY-2584702 (tosylate salt) Chemical Properties,Usage,Production
Uses
LY-2584702 is a p70 S6 kinase inhibitor with anti-tumor activity.
Biological Activity
LY2584702 is an orally active, ATP-competitive, potent and selective ribosomal protein S6 kinase (p70 S6 kinase, p70S6K, S6K1) inhibitor (IC50 = 4 nM; selective over 83 other kinases and 45 cell surface markers). LY2584702 inhibits HCT116 cellular S6 phosphorylation (IC50 0.1-0.24 μM) and shows anti-tumor efficacy in U87MG glioblastoma and HCT116 colon carcinoma xenograft models in vivo (2.5 mg/kg bid. po.).
LY-2584702 (tosylate salt) Preparation Products And Raw materials
Raw materials
Preparation Products
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