3-Hydroxy-4-iodobenzoic acid
- Product Name
- 3-Hydroxy-4-iodobenzoic acid
- CAS No.
- 58123-77-6
- Chemical Name
- 3-Hydroxy-4-iodobenzoic acid
- Synonyms
- RARECHEM AL BE 0964;3-Hydroxy-4-Iodobenzoic;3-HYDROXY-4-IODOBENZOIC ACID;4-IODO-3-HYDROXY BENZOIC ACID;Benzoic acid, 3-hydroxy-4-iodo-;3-Hydroxy-4-iodobenzoic Acid >3-Hydroxy-4-iodobenzoic acid 97%;Acetylchloride,2-[6-(trifluoromethyl)phenoxy]-
- CBNumber
- CB5274653
- Molecular Formula
- C7H5IO3
- Formula Weight
- 264.02
- MOL File
- 58123-77-6.mol
3-Hydroxy-4-iodobenzoic acid Property
- Melting point:
- 225-229 °C
- Boiling point:
- 319.8±32.0 °C(Predicted)
- Density
- 2.155±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- form
- powder to crystal
- pka
- 3.90±0.10(Predicted)
- color
- White to Almost white
- Sensitive
- Light Sensitive
- InChI
- InChI=1S/C7H5IO3/c8-5-2-1-4(7(10)11)3-6(5)9/h1-3,9H,(H,10,11)
- InChIKey
- UABBBWVTEWIIMN-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C1=CC=C(I)C(O)=C1
Safety
- Hazard Codes
- T,Xi
- Risk Statements
- 25-37/38-41-36/37/38
- Safety Statements
- 26-36/39-45-37/39
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- Hazard Note
- Irritant
- HazardClass
- 6.1
- PackingGroup
- Ⅲ
- HS Code
- 29225090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- 664057
- Product name
- 3-Hydroxy-4-iodobenzoic acid
- Purity
- 97%
- Packaging
- 1g
- Price
- $149
- Updated
- 2023/01/07
- Product number
- H1496
- Product name
- 3-Hydroxy-4-iodobenzoic Acid
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $109
- Updated
- 2025/07/31
- Product number
- H1496
- Product name
- 3-Hydroxy-4-iodobenzoic Acid
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $385
- Updated
- 2025/07/31
- Product number
- H943658
- Product name
- 3-Hydroxy-4-iodobenzoic acid
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- H943658
- Product name
- 3-Hydroxy-4-iodobenzoic acid
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
3-Hydroxy-4-iodobenzoic acid Chemical Properties,Usage,Production
Chemical Properties
White solid
Synthesis
99-06-9
58123-77-6
General procedure for the synthesis of 3-hydroxy-4-iodobenzoic acid from m-hydroxybenzoic acid: 21.0 g (0.52 mol, 1.05 eq.) of sodium hydroxide and 78.7 g (0.52 mol, 1.05 eq.) of sodium iodide were sequentially added to a 700 mL methanol solution containing 69.1 g (0.5 mol, 1 eq.) of 3-hydroxybenzoic acid. The reaction mixture was cooled to 0 °C, followed by slow dropwise addition of aqueous sodium hypochlorite (0.52 mol, 1.05 eq.). The reaction system was kept stirred at 0-5 °C for 2 h, after which stirring was continued overnight at room temperature. Upon completion of the reaction, methanol was removed by evaporation followed by acidification of the reaction mixture with concentrated hydrochloric acid solution. The precipitated product was collected by filtration, washed with water and dried to give 121 g of 3-hydroxy-4-iodobenzoic acid as an off-white solid in 92% yield.
References
[1] Patent: WO2006/18325, 2006, A1. Location in patent: Page/Page column 25-26
[2] Patent: WO2006/18326, 2006, A1. Location in patent: Page/Page column 78
[3] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1995, # 9, p. 1103 - 1114
[4] Beilstein Journal of Organic Chemistry, 2009, vol. 5,
[5] Journal of the Chemical Society - Perkin Transactions 1, 1999, # 15, p. 2077 - 2086
3-Hydroxy-4-iodobenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
3-Hydroxy-4-iodobenzoic acid Suppliers
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23671
- Advantage
- 75
View Lastest Price from 3-Hydroxy-4-iodobenzoic acid manufacturers
- Product
- 3-Hydroxy-4-iodobenzoic acid 58123-77-6
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1000kg
- Release date
- 2025-06-29
- Product
- 3-Hydroxy-4-iodobenzoic acid 58123-77-6
- Price
- US $3.00-9.00/KG
- Min. Order
- 0.1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2025-06-19
- Product
- 3-hydroxy-4-iodobenzoic acid 58123-77-6
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27