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Idarubicin

Product Name
Idarubicin
CAS No.
58957-92-9
Chemical Name
Idarubicin
Synonyms
DMDR;4-DMD;CS-704;IMI-30;IDAMYCIN;nsc-256439;IDARUBICIN;IDARUBICIN HCL;IMI-30：NSC-256439;Idarubicin USP/EP/BP
CBNumber
CB5283235
Molecular Formula
C26H27NO9
Formula Weight
497.49
MOL File
58957-92-9.mol
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Idarubicin Property

Boiling point:
589.46°C (rough estimate)
Density 
1.3477 (rough estimate)
refractive index 
1.6000 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
form 
solid
pka
pKa 4.73± 0.21 (Uncertain)
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Safety

Hazard Codes 
T+
Risk Statements 
60-61-28-40
Safety Statements 
53-45
RIDADR 
UN 2811 6.1/PG 2
WGK Germany 
3
RTECS 
HB7877000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0002970
Product name
Idarubicin
Purity
95.00%
Packaging
10MG
Price
$494.55
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0002970
Product name
Idarubicin
Purity
95.00%
Packaging
25MG
Price
$840.8
Updated
2021/12/16
AvaChem
Product number
2183B
Product name
Idarubicin
Packaging
5mg
Price
$59
Updated
2021/12/16
AvaChem
Product number
2183B
Product name
Idarubicin
Packaging
10mg
Price
$95
Updated
2021/12/16
AvaChem
Product number
2183B
Product name
Idarubicin
Packaging
25mg
Price
$195
Updated
2021/12/16
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Idarubicin Chemical Properties,Usage,Production

Chemical Properties

Idarubicin Hydrochloride: C????H????NO??HCl. [57852-57-0]. Bright orange crystalline powder, melting point 183–185°C; melting point 172–174°C has also been reported. [α]D20+205° (C=0.1, methanol); also reported as [α]D20+188° (C=0.10, methanol).

Uses

Antineoplastic.

Indications

Idarubicin (Idamycin) differs from its parent compound, daunorubicin, by the absence of the methoxy group in the anthracycline ring structure. Its mechanisms of action and resistance are similar to those of doxorubicin and daunorubicin; however, it is more lipophilic and more potent than these other anthracyclines. Idarubicin undergoes extensive hepatic metabolism and biliary excretion. Adverse reactions of idarubicin are similar to those of its congeners.

Definition

ChEBI: Idarubicin is a monosaccharide derivative, an anthracycline antibiotic and a deoxy hexoside. It derives from a hydride of a tetracene.

brand name

Zavedos ; Idamycin/Idamycin PFS

Mechanism of action

Idarubicin is an anthracycline antitumor drug. It mainly exerts its therapeutic effect on acute leukemia by binding to DNA and inhibiting the activity of topoisomerase II, thereby disrupting DNA replication and transcription and causing DNA damage and cell death.

Clinical Use

Idarubicin is a chemotherapy drug used to treat acute myeloid leukaemia (AML) and acute lymphoblastic leukaemia (ALL).

IC 50

Topoisomerase II

Idarubicin Preparation Products And Raw materials

Raw materials

Argon 1,4-Dioxane Dichloromethane Acetic acid DOWEX(R) 50WX4 HYDROGEN FORM Magnesium sulfate

Preparation Products

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Idarubicin Suppliers

China 107 Europe 3 Germany 2 India 2 Switzerland 1 United Kingdom 8 United States 14 Global 137
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
Advantage
70
Wuhan Sunrise Technology Development Co., Ltd.
Tel
27-027-83314682 13554138826
Fax
+86 (27) 8331-4682
Email
whsrtech@vip.163.com
Country
China
ProdList
246
Advantage
62
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
NCE Biomedical Co.,Ltd.
Tel
4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
Fax
+86-27-87599188
Country
China
ProdList
1493
Advantage
55
Synchem OHG
Tel
+49 5662 408730
Fax
+49 5662 4087320
Email
info@synchem.de
Country
Germany
ProdList
4705
Advantage
70
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66028182 18626450290
Email
yftan@aikonchem.com
Country
China
ProdList
16679
Advantage
50
AN PharmaTech Co Ltd
Tel
86(21)68097365
Fax
86(21)33321566
Email
sales@anpharma.net
Country
China
ProdList
4891
Advantage
55
Shanghai Biolang biotechnology Co.,Ltd
Tel
17764003753
Fax
13669031409
Email
2326587775@qq.com
Country
China
ProdList
188
Advantage
55
Shanghai Biolang biotechnology Co.,Ltd
Tel
17764003753
Fax
13669031409
Email
2326587775@qq.com
Country
China
ProdList
188
Advantage
55
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View Lastest Price from Idarubicin manufacturers

Shaanxi Xianhe Biotech Co., Ltd
Product
Idarubicin 58957-92-9
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
1000kg
Release date
2025-04-17
Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
Idarubicin 58957-92-9
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20tons
Release date
2024-04-15
Zhuozhou Wenxi import and Export Co., Ltd
Product
idarubicin 58957-92-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-11

58957-92-9, IdarubicinRelated Search:

Acetyl chloride 6-Aminocaproic acid Daunorubicin ALTRENOGEST CHLOROPHOSPHONAZO III Acetylacetone p-Anisaldehyde p-Anisidine Acetyl coenzyme A sodium salt (Trifluoromethoxy)benzene Glycine Anisole Enalaprilat Eplerenone tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate IDARUBICINOL Nemorubicin IDARUBICIN HCL,IDARUBICIN HYDROCHLORIDE,Idarubicin HCL for research

  • 11-trihydroxy-(7s-cis)-alpha-l-lyxo-hexopyranosyl)oxy)-
  • 4-demethoxy-daunomyci
  • 4-demethoxydaunomycin
  • 4-demethoxydaunorubicin
  • 4-Demethoxy-daunorubicin
  • 7,8,9,10-tetrahydro-9-acetyl-7-((3-amino-2,3,6-trideoxy-12-naphthacenedione
  • nsc-256439
  • (7S)-9-Acetyl-7β-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9β,11-trihydroxy-5,12-naphthacenedione
  • (7S,9S)-9-Acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione
  • CS-704
  • Idarubicin ( 4-Demethoxydaunorubicin
  • (7S-CIS)-9-ACETYL-7-[(3-AMINO-2,3,6-TRIDEOXY-ALPHA-L-LYXO-HEXOPYRANOSYL)OXY]-7,8,9,10-TETRAHYDRO-6,9,11-TRIHYDROXY-5,12-NAPHTHACENEDIONE
  • DMDR
  • IMI-30
  • IDAMYCIN
  • IDARUBICIN
  • IDARUBICIN HCL
  • 5,12-Naphthacenedione, 9-acetyl-7-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-, (7S,9S)-
  • 1-Demethoxydaunorubicin
  • 4-DMD
  • 5,12-Naphthacenedione, 9-acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-, (7S,9S)-
  • 5,12-Naphthacenedione, 9-acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-, (7S-cis)-
  • Demethoxydaunorubicin
  • Idarubicin HCL(BICINS)
  • (7S,9S)-9-Acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione
  • (7S-cis)-9-Acetyl-7-[(3-amincr2，3，6-trideoxy-α-L-lyxohexopyranosyl)oxy]-7，8，9，10-tetrahydro-6，9，11-trihydroxy-5，12-naphthacenedione
  • IMI-30：NSC-256439
  • Idarubicin USP/EP/BP
  • IdarubicinQ: What is Idarubicin Q: What is the CAS Number of Idarubicin Q: What is the storage condition of Idarubicin Q: What are the applications of Idarubicin
  • Idarubicin（58957-92-9）
  • 58957-92-9
  • C26H27NO9
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  • Cell Signaling and Neuroscience
  • Cell Biology
  • BioChemical
  • DNA Synthesis Inhibitors
  • DNA metabolism
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