3-Nitrophenylhydrazine hydrochloride
- Product Name
- 3-Nitrophenylhydrazine hydrochloride
- CAS No.
- 636-95-3
- Chemical Name
- 3-Nitrophenylhydrazine hydrochloride
- Synonyms
- 3-NitrophenylhydrazineHcl;M-NITROPHENYLHYDRAZINE HCL;3-Nitrophenylhydrazine Hcl 98%;M-Nitrophenylhydrazinium chloride;M-NITROPHENYLHYDRAZINE HYDROCHLORIDE;3-NITROPHENYLHYDRAZINE HYDROCHLORIDE;3-nitrophenylhydrazinium(1+) chloride;3-NITROPHENYLHYDRAZINE HYDROCHLORIDE 98%;3-NITROPHENYLHYDRAZINE HYDROCHLORIDE, 98 %;3-Nitrophenylhydrazine Hydrochloride, 97+%
- CBNumber
- CB5284737
- Molecular Formula
- C6H8ClN3O2
- Formula Weight
- 189.6
- MOL File
- 636-95-3.mol
3-Nitrophenylhydrazine hydrochloride Property
- Melting point:
- 210 °C (dec.)(lit.)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- DMSO, Methanol (Slightly)
- form
- Solid
- color
- Yellow to Dark Yellow
- BRN
- 3569013
- CAS DataBase Reference
- 636-95-3(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 26-37/39-36
- RIDADR
- 2811
- WGK Germany
- 3
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 2928009090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- N21804
- Product name
- 3-Nitrophenylhydrazine hydrochloride
- Purity
- 98%
- Packaging
- 5g
- Price
- $52.2
- Updated
- 2025/07/31
- Product number
- N21804
- Product name
- 3-Nitrophenylhydrazine hydrochloride
- Purity
- 98%
- Packaging
- 25g
- Price
- $155
- Updated
- 2025/07/31
- Product number
- N0232
- Product name
- 3-Nitrophenylhydrazine Hydrochloride
- Purity
- >98.0%(T)
- Packaging
- 5g
- Price
- $51
- Updated
- 2025/07/31
- Product number
- N0232
- Product name
- 3-Nitrophenylhydrazine Hydrochloride
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $139
- Updated
- 2025/07/31
- Product number
- N545130
- Product name
- 3-Nitrophenylhydrazine Hydrochloride
- Packaging
- 25g
- Price
- $110
- Updated
- 2021/12/16
3-Nitrophenylhydrazine hydrochloride Chemical Properties,Usage,Production
Chemical Properties
YELLOW CRYSTALLINE POWDER
Uses
3-Nitrophenylhydrazine Hydrochloride acts as a reagent in the preparation of isosteviol-fused pyrazolines and pyrazoles as potential anticancer agents, preparation of pyrazolobenzothiazines as inhibitors of hepatitis C virus replication.
Synthesis
99-09-2
51516-96-2
Example 28: Synthesis of 3-methyl-1H-indol-6-amine 1. 3-Nitroaniline (27.6 g, 0.2 mol) was dissolved in a mixed solution of water (40 mL) and 37% hydrochloric acid (40 mL). 2. A solution of sodium nitrite (NaNO2, 13.8 g, 0.2 mol) in water (60 mL) was slowly added to the above solution at 0 °C. 3. Subsequently, a 37% hydrochloric acid (100 mL) solution of tin chloride dihydrate (SnCl2-2H2O, 135.5 g, 0.6 mol) was added, maintaining the reaction temperature at 0 °C. 4. After continuous stirring of the reaction mixture at 0 °C for 0.5 h, the insoluble solid was separated by filtration and washed with cold water to afford (3-nitrophenyl)hydrazine hydrochloride (27.6 g, 73% yield). Example 49: Synthesis of 6-amino-1H-indole-2-carbonitrile 1. 3-Nitroaniline (28 g, 0.20 mol) was dissolved in a mixture of water (40 mL) and 37% hydrochloric acid (40 mL). 2. A solution of sodium nitrite (NaNO2, 14 g, 0.20 mol) in water (60 mL) was slowly added to the above solution at 0 °C. 3. Subsequently, a 37% hydrochloric acid (100 mL) solution of tin chloride dihydrate (SnCl2-2H2O, 140 g, 0.60 mol) was added, maintaining the reaction temperature at 0 °C. 4. After continuous stirring of the reaction mixture at 0 °C for 0.5 h, the insoluble solid was separated by filtration and washed with cold water to afford (3-nitrophenyl)hydrazine hydrochloride (28 g, 73% yield).
References
[1] Patent: US2007/244159, 2007, A1. Location in patent: Page/Page column 110-111; 138
[2] Patent: US2012/309758, 2012, A1. Location in patent: Page/Page column 67
[3] Patent: US2015/231142, 2015, A1. Location in patent: Paragraph 0397; 1632; 1744
[4] Organic Preparations and Procedures International, 1991, vol. 23, # 3, p. 357 - 364
[5] Journal of Agricultural and Food Chemistry, 2014, vol. 62, # 2, p. 381 - 390
3-Nitrophenylhydrazine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Nitrophenylhydrazine hydrochloride manufacturers
- Product
- 3-Nitrophenylhydrazine hydrochloride 636-95-3
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99.5%
- Supply Ability
- 100 tons
- Release date
- 2022-02-21