ChemicalBook > CAS DataBase List > 2-Fluorophenylacetic acid

2-Fluorophenylacetic acid

Product Name
2-Fluorophenylacetic acid
CAS No.
451-82-1
Chemical Name
2-Fluorophenylacetic acid
Synonyms
O-fluorine acid;RARECHEM AL BO 0110;2-Fluorophenylacetic;o-flurophenylacetic acid;2-Fluorphenylessigsaeure;2-fluoro-benzeneaceticaci;2-FLUOROPHENYLACETIC ACID;O-FLUOROPHENYLACETIC ACID;2-fluoro-benzeneacetic acid;2-Fluorophenylaceticacid97%
CBNumber
CB5297100
Molecular Formula
C8H7FO2
Formula Weight
154.14
MOL File
451-82-1.mol
More
Less

2-Fluorophenylacetic acid Property

Melting point:
60-62 °C (lit.)
Boiling point:
203.5°C (rough estimate)
Density 
1.1850 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Sparingly), Methanol (Slightly)
form 
Solid
pka
4.01±0.10(Predicted)
color 
Off-White
BRN 
775955
InChI
InChI=1S/C8H7FO2/c9-7-4-2-1-3-6(7)5-8(10)11/h1-4H,5H2,(H,10,11)
InChIKey
RPTRFSADOICSSK-UHFFFAOYSA-N
SMILES
C1(CC(O)=O)=CC=CC=C1F
CAS DataBase Reference
451-82-1(CAS DataBase Reference)
NIST Chemistry Reference
O-fluorophenylacetic acid(451-82-1)
EPA Substance Registry System
Benzeneacetic acid, 2-fluoro- (451-82-1)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
38-36/37/38
Safety Statements 
22-24/25-36/37/39-27-26
WGK Germany 
3
F 
13
TSCA 
T
HazardClass 
IRRITANT
HS Code 
29163990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
208949
Product name
2-Fluorophenylacetic acid
Purity
98%
Packaging
10g
Price
$103
Updated
2023/06/20
TCI Chemical
Product number
F0205
Product name
2-Fluorophenylacetic Acid
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$27
Updated
2024/03/01
TCI Chemical
Product number
F0205
Product name
2-Fluorophenylacetic Acid
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$70
Updated
2024/03/01
Alfa Aesar
Product number
A10596
Product name
2-Fluorophenylacetic acid, 98+%
Packaging
10g
Price
$44.65
Updated
2024/03/01
Alfa Aesar
Product number
A10596
Product name
2-Fluorophenylacetic acid, 98+%
Packaging
50g
Price
$136.65
Updated
2024/03/01
More
Less

2-Fluorophenylacetic acid Chemical Properties,Usage,Production

Chemical Properties

white to off-white shiny crystals or crystalline

Uses

2-Fluorophenylacetic acid was used:

  • in the synthesis of thiazolino[3,2-c]pyrimidin-5,7-diones and N-[2-(3,4-dichlorophenyl)-ethyl]-N′-[2-(2-fluorophenyl)-ethyl]-ethane-1,2-diamine
  • as chiral derivatizing agent for determination of enantiomeric composition of chiral, nonracemic compounds by 19F NMR spectroscopy

General Description

2-Fluorophenylacetic acid is chiral derivatizing agent for determination of enantiomeric composition of chiral, nonracemic compounds by 19F NMR spectroscopy.

Synthesis

The Schlenk tube was heated under a high vacuum, pre-dried with calcium chloride, and filled with CO2 gas. Bis(4-methoxyphenyl)zinc magnesium chloride lithium chloride (12.8 ml, 0:39 M in THF, 5.0 mmol) was added, and CO2 was passed through the solution for 5 minutes. The reaction mixture was stirred at 25 °C for 6 hours. Diethyl ether (50 ml) was added, and the organic phase was extracted with 2M NaOH (3×50 ml). The combined aqueous phases were acidified with 2M HCl (pH <5) and extracted with diethyl ether (3×50 ml). The combined organic phases were dried over sodium sulfate, and the solvent was removed in vacuo. 2-Fluorophenylacetic acid was obtained in a yield of 100%.

2-Fluorophenylacetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2-Fluorophenylacetic acid Suppliers

Americas 1 Belgium 3 China 320 Europe 3 France 1 Germany 9 India 16 Italy 1 Japan 5 Slovakia 1 Switzerland 3 Ukraine 1 United Kingdom 20 United States 50 Global 434
Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd.
Tel
133-96369453 18678026865
Fax
0536-2101172
Email
sdfantai@163.com
Country
China
ProdList
869
Advantage
58
Beijing Holiyang Chemical Co. Ltd.
Tel
13718199399
Fax
QQ : 206661479
Email
holiyangchem@163.com
Country
China
ProdList
3381
Advantage
56
Nanjing Dilu Pharmaceutical Co., Ltd
Tel
18014482516
Email
977144864@qq.com
Country
China
ProdList
402
Advantage
58
Zibo Run Hang Seng material Technology Co., LTD
Tel
13561657928 13561657928
Email
2388773670@qq.com
Country
China
ProdList
294
Advantage
58
Cangzhou Enke Pharma Tech Co.,ltd.
Tel
0317-5106596 15533709196
Email
1154424302@qq.com
Country
China
ProdList
2050
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing dtftchem Technology Co., Ltd.
Tel
010-60275820 13031183356
Fax
010-60270825
Email
elainezt@sina.com
Country
China
ProdList
1390
Advantage
62
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44733
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12443
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9407
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8164
Advantage
52
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Nanjing Vital Chemical Co., Ltd.
Tel
Please Send Email 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
4378
Advantage
65
Changzhou Joyous Chemical Co., Ltd.
Tel
0519-85607258
Fax
0519-85607278
Email
sales@joyouschem.com
Country
China
ProdList
294
Advantage
60
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6134
Advantage
55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19915
Advantage
55
SuZhou ShiYa Biopharmaceuticals, Inc.
Tel
86(512)5235 8471 17715136450
Fax
86(512)5235 6881
Email
sales@shiyabiopharm.com
Country
China
ProdList
4169
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 1316706386
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9545
Advantage
55
Bsisun HK Imoprt And Export Company Limited
Tel
+86-18068513926
Fax
0086-519-85153711
Country
China
ProdList
1277
Advantage
55
Cantotech Chemicals, Ltd.
Tel
86-0755-86635001
Fax
86-0755-22642228
Email
cantotech@126.com
Country
China
ProdList
4566
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Hunan Furui Biopharma Technology Co., Ltd.
Tel
15902102743
Fax
0731-57805668
Email
shelley@furuipharma.com
Country
China
ProdList
453
Advantage
55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
+86-28-85122536 85324413
Fax
+86-28-85326443
Email
market@astatech.cn
Country
China
ProdList
8026
Advantage
55
Shanghai Huikai Chemical Technology Co., Ltd.
Tel
021-61995394 18916691159
Email
chemicalsea@163.com
Country
China
ProdList
1972
Advantage
58
Quzhou Juhua Friendship Co., Ltd
Tel
0570-3066667
Fax
0570-3063388
Country
China
ProdList
3930
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828 4008675858
Fax
+86-512-56316826
Email
sales@amateksci.com
Country
China
ProdList
9893
Advantage
55
Beijing Universal Century Technology Co., Ltd.
Tel
400-8706899
Fax
400-8706899
Email
hysj_bj.com
Country
China
ProdList
3583
Advantage
55
Hubei XinyuanShun Chemical Co., Ltd.
Tel
13971561712, 13995564702, 027-50664929
Fax
027-50664927
Email
hbeixys2001@163.com
Country
China
ProdList
3120
Advantage
55
Shanghai Meishui Chemical Technology Co., Ltd
Tel
021-60549325 18616193163
Fax
021-33250306
Country
China
ProdList
4526
Advantage
56
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9978
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41457
Advantage
60
Chemwill Asia Co.,Ltd.
Tel
86-21-51086038
Fax
86-21-51861608
Country
China
ProdList
2930
Advantage
58
More
Less

View Lastest Price from 2-Fluorophenylacetic acid manufacturers

Hebei Mujin Biotechnology Co.,Ltd
Product
2-Fluorophenylacetic acid 451-82-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-09-08
Hebei Mujin Biotechnology Co.,Ltd
Product
2-Fluorophenylacetic acid 451-82-1
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000KG/month
Release date
2024-08-23
Speranza Chemical Co., Ltd.
Product
2-Fluorophenylacetic acid 451-82-1
Price
US $170.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200tons/ year
Release date
2020-03-11

451-82-1, 2-Fluorophenylacetic acidRelated Search:

Stearic acid 2-Fluorobenzonitrile 1,2-Difluorobenzene 2-Hydroxyphenylacetic acid 4-Fluorobenzaldehyde Transfluthrin 2-Chlorophenylacetic acid Florfenicol Ethyl 2-(Chlorosulfonyl)acetate Folic acid Citric acid 2-Fluorobenzyl cyanide 2'-Fluoroacetophenone 2-Fluorobenzoic acid alpha-Chloro-o-fluorotoluene 2-(2'-FLUOROPHENYL)-ACETYL-CHLORIDE 2-Fluoropropiophenone 2-Chlorobenzyl alcohol

  • RARECHEM AL BO 0110
  • O-FLUOROPHENYLACETIC ACID
  • 2-FLUOROPHENYLACETIC ACID
  • 2-fluoro-benzeneaceticaci
  • Acetic acid, (o-fluorophenyl)-
  • Benzeneacetic acid, 2-fluoro-
  • o-Fluorophenylacetic Acid 2-Fluorophenylacetic Acid
  • 2-Fluorophenylacetic acid, 98+%
  • 2-Fluorophenylacetic acid 97%
  • 2-Fluorophenylaceticacid97%
  • 2-fluoro-benzeneacetic acid
  • 2-Fluorophenylacetic
  • O-fluorine acid
  • o-flurophenylacetic acid
  • 2-Fluorophenylacetic acid, 98% 10GR
  • Orthofluorophenyl acetic acid
  • Adjacent fluorine benzene acetic acid
  • o-2-Fluorophenylacetic Acid
  • 2-Fluorphenylessigsaeure
  • 2-Fluorophenylacetic acid ISO 9001：2015 REACH
  • 451-82-1
  • FA - FL
  • Organic Building Blocks
  • C8
  • Carbonyl Compounds
  • Carboxylic Acids
  • Building Blocks
  • Analytical Standards
  • Alphabetic
  • Analytical Chromatography Product Catalog
  • Aryl Fluorinated Building Blocks
  • Building Blocks
  • C7-C8
  • Carbonyl Compounds
  • Carboxylic Acids
  • Chemical Synthesis
  • Fluorinated Building Blocks
  • Organic Building Blocks
  • Organic Fluorinated Building Blocks
  • Other Fluorinated Organic Building Blocks
  • Imidazoles
  • Aromatic Phenylacetic Acids and Derivatives
  • Fluorobenzene
  • Phenylacetic acid
  • C8
  • Carbonyl Compounds
  • Carboxylic Acids
  • Alphabetic
  • F
  • FA - FL
  • Phenylacetic acid series