ChemicalBook > CAS DataBase List > 2-Fluorophenylacetic acid
2-Fluorophenylacetic acid
- Product Name
- 2-Fluorophenylacetic acid
- CAS No.
- 451-82-1
- Chemical Name
- 2-Fluorophenylacetic acid
- Synonyms
- O-fluorine acid;RARECHEM AL BO 0110;2-Fluorophenylacetic;o-flurophenylacetic acid;2-Fluorphenylessigsaeure;2-fluoro-benzeneaceticaci;2-FLUOROPHENYLACETIC ACID;O-FLUOROPHENYLACETIC ACID;2-fluoro-benzeneacetic acid;2-Fluorophenylaceticacid97%
- CBNumber
- CB5297100
- Molecular Formula
- C8H7FO2
- Formula Weight
- 154.14
- MOL File
- 451-82-1.mol
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2-Fluorophenylacetic acid Property
- Melting point:
- 60-62 °C (lit.)
- Boiling point:
- 203.5°C (rough estimate)
- Density
- 1.1850 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Sparingly), Methanol (Slightly)
- form
- Solid
- pka
- 4.01±0.10(Predicted)
- color
- Off-White
- BRN
- 775955
- InChI
- InChI=1S/C8H7FO2/c9-7-4-2-1-3-6(7)5-8(10)11/h1-4H,5H2,(H,10,11)
- InChIKey
- RPTRFSADOICSSK-UHFFFAOYSA-N
- SMILES
- C1(CC(O)=O)=CC=CC=C1F
- CAS DataBase Reference
- 451-82-1(CAS DataBase Reference)
- NIST Chemistry Reference
- O-fluorophenylacetic acid(451-82-1)
- EPA Substance Registry System
- Benzeneacetic acid, 2-fluoro- (451-82-1)
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Safety
- Hazard Codes
- Xi
- Risk Statements
- 38-36/37/38
- Safety Statements
- 22-24/25-36/37/39-27-26
- WGK Germany
- 3
- F
- 13
- TSCA
- T
- HazardClass
- IRRITANT
- HS Code
- 29163990
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 208949
- Product name
- 2-Fluorophenylacetic acid
- Purity
- 98%
- Packaging
- 10g
- Price
- $103
- Updated
- 2023/06/20
TCI Chemical
- Product number
- F0205
- Product name
- 2-Fluorophenylacetic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $27
- Updated
- 2024/03/01
TCI Chemical
- Product number
- F0205
- Product name
- 2-Fluorophenylacetic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $70
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- A10596
- Product name
- 2-Fluorophenylacetic acid, 98+%
- Packaging
- 10g
- Price
- $44.65
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- A10596
- Product name
- 2-Fluorophenylacetic acid, 98+%
- Packaging
- 50g
- Price
- $136.65
- Updated
- 2024/03/01
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2-Fluorophenylacetic acid Chemical Properties,Usage,Production
Chemical Properties
white to off-white shiny crystals or crystalline
Uses
2-Fluorophenylacetic acid was used:
- in the synthesis of thiazolino[3,2-c]pyrimidin-5,7-diones and N-[2-(3,4-dichlorophenyl)-ethyl]-N′-[2-(2-fluorophenyl)-ethyl]-ethane-1,2-diamine
- as chiral derivatizing agent for determination of enantiomeric composition of chiral, nonracemic compounds by 19F NMR spectroscopy
General Description
2-Fluorophenylacetic acid is chiral derivatizing agent for determination of enantiomeric composition of chiral, nonracemic compounds by 19F NMR spectroscopy.
Synthesis
The Schlenk tube was heated under a high vacuum, pre-dried with calcium chloride, and filled with CO2 gas. Bis(4-methoxyphenyl)zinc magnesium chloride lithium chloride (12.8 ml, 0:39 M in THF, 5.0 mmol) was added, and CO2 was passed through the solution for 5 minutes. The reaction mixture was stirred at 25 °C for 6 hours. Diethyl ether (50 ml) was added, and the organic phase was extracted with 2M NaOH (3×50 ml). The combined aqueous phases were acidified with 2M HCl (pH <5) and extracted with diethyl ether (3×50 ml). The combined organic phases were dried over sodium sulfate, and the solvent was removed in vacuo. 2-Fluorophenylacetic acid was obtained in a yield of 100%.
2-Fluorophenylacetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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2-Fluorophenylacetic acid Suppliers
- Tel
- 03-36680489
- Fax
- 03-3668-0520
- Sales-JP@TCIchemicals.com
- Country
- Japan
- ProdList
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- Advantage
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- Fax
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- Country
- Japan
- ProdList
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- Advantage
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- Tel
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- Fax
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- info@shigematsu-bio.com
- Country
- Japan
- ProdList
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- Advantage
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- Tel
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- Country
- Japan
- ProdList
- 6819
- Advantage
- 80
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- Fax
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- reag-info@gms.kanto.co.jp
- Country
- Japan
- ProdList
- 6756
- Advantage
- 74
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View Lastest Price from 2-Fluorophenylacetic acid manufacturers
Speranza Chemical Co., Ltd.
- Product
- 2-Fluorophenylacetic acid 451-82-1
- Price
- US $170.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200tons/ year
- Release date
- 2020-03-11
Hebei Chuanghai Biotechnology Co,.LTD
- Product
- 2-Fluorophenylacetic acid 451-82-1
- Price
- US $9.00/KG
- Min. Order
- 1KG
- Purity
- 99.9
- Supply Ability
- 1 ton
- Release date
- 2024-08-20
Hebei Mojin Biotechnology Co.,Ltd
- Product
- 2-Fluorophenylacetic acid 451-82-1
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2024-08-23
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