ChemicalBook > CAS DataBase List > 1,3-Adamantanedicarboxylic acid

1,3-Adamantanedicarboxylic acid

Product Name
1,3-Adamantanedicarboxylic acid
CAS No.
39269-10-8
Chemical Name
1,3-Adamantanedicarboxylic acid
Synonyms
ADAMANTANE-1,3-DICARBOXYLIC ACID;(1s,3s,5r,7r)-AdaMantane-1,3-dicarboxylic acid;AKOS BC-0656;1,3-DICARBOXYADAMANTANE;adamantane-1,3-dicarboxylate;1,3-ADAMANTANEDICARBOXYLIC ACID;1,3-Adamantanedicarboxylic Acid >1,3-Adamantanedicarboxylic acid 98%;Tricyclo[3.3.1.13,7]decane-1,3-dicarboxylic acid;tricyclo(3.3.1.1(sup3,7))decane-1,3-dicarboxylicacid
CBNumber
CB5316047
Molecular Formula
C12H16O4
Formula Weight
224.25
MOL File
39269-10-8.mol
More
Less

1,3-Adamantanedicarboxylic acid Property

Melting point:
276-278 °C (lit.)
Boiling point:
380.6±15.0 °C(Predicted)
Density 
1.461±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Sparingly), Methanol (Slightly, Heated)
form 
Solid
pka
4.24±0.40(Predicted)
color 
White to Off-White
CAS DataBase Reference
39269-10-8(CAS DataBase Reference)
More
Less

Safety

Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
WGK Germany 
3
RTECS 
YD1994000
HS Code 
29172090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
340820
Product name
1,3-Adamantanedicarboxylic acid
Purity
98%
Packaging
1G
Price
$120
Updated
2023/01/07
TCI Chemical
Product number
A1358
Product name
1,3-Adamantanedicarboxylic Acid
Purity
>97.0%(GC)(T)
Packaging
5g
Price
$73
Updated
2024/03/01
TCI Chemical
Product number
A1358
Product name
1,3-Adamantanedicarboxylic Acid
Purity
>97.0%(GC)(T)
Packaging
25g
Price
$246
Updated
2024/03/01
Alfa Aesar
Product number
H60081
Product name
Adamantane-1,3-dicarboxylic acid, 98%
Packaging
1g
Price
$53.65
Updated
2024/03/01
Alfa Aesar
Product number
H60081
Product name
Adamantane-1,3-dicarboxylic acid, 98%
Packaging
5g
Price
$211.65
Updated
2024/03/01
More
Less

1,3-Adamantanedicarboxylic acid Chemical Properties,Usage,Production

Uses

1,3-Adamantanedicarboxylic acid is a carboxylic acid derivative of adamantane. It is widely used in drug industry, polymer synthesis and fine chemicals as key intermediates. It is also used as antidepressants or antiparkinsonic drugs in clinical practice.

Preparation

1,3-Adamantanedicarboxylic acid was synthesized from 1-adamantane carboxylic acid by one-pot method. In this process, the ratio of mixed acid (nitric acid and sulfuric acid) have important effect on the yield, the role of sulfuric acid not only is solvent, but also can improve the oxidate ability of nitric acid.
Efficient Synthesis of 1,3-Adamantanedicarboxylic Acid and 1,3-Diaminoadamantane

Reaction: 1-Adamantane carboxylic acid (20 g), nitric acid (65 %, 20 mL) and sulfuric acid (98 %, 160 mL) were placed in a three-necked roundbottom flask fitted with an efficient magnetic stirrer and a thermometer. Cooled to 0 oC and held at 0 oC, anhydrous formic acid (80 %, 70 mL) was added dropwise in 5 h and reacted for 1 h. poured to crushed ice, filtered and then washed the precipitate several times with water to give a white solid. Then the white solid was dissolved in aqueous NaOH solution and the upper clear solution was separated and acidified by HCl to pH = 3. Filtered, washed with water, dried in vacuum, recrystallized from ethanol. White solid, yield 22.9 g (92 %). m.p.: 275- 276 oC
1H NMR (DMSO-d6, 400 MHz) δ: 1.616 (m, 2H), 1.691-1.727 (m, 4H), 1.759-1.791 (m, 4H), 1.850-1.882 (m, 2H), 2.059 (m, 1H), 12.062 (br, s, 2H, COOH); 13C NMR (100 MHz, DMSO-d6) δ 27.37 (C-5, C-7), 34.98 (C-6), 37.66 (C-4, C-8, C-9, C-10), 39.78 (C-2), 39.89 (C-2, C-3), 177.76 (COOH). IR (KBr, νmax, cm-1) : 2913, 2851, 2636, 1691, 1451, 1410, 1344, 1249, 1103, 1084, 952, 743, 670, 528; Anal. calcd for C12H16O4: C 64.29, H 7.14; found C 64.55, H 7.22.

Purification Methods

Dissolve the acid in aqueous NaOH, treat with charcoal, filter and acidify with dilute HCl. It crystallises from MeOH. [Stetter & Wulff Chem Ber 93 1366 1960, Beilstein 9 III 4066, 9 IV 2997.]

1,3-Adamantanedicarboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1,3-Adamantanedicarboxylic acid Suppliers

Americas 1 China 156 Europe 2 France 1 Germany 5 India 6 Japan 5 Switzerland 1 Ukraine 1 United Kingdom 12 United States 20 Global 210
TIANJIN MINXIANG BIOMEDICAL INC.
Tel
022-59596766 13313219033 18222332696
Fax
86-22-88718329
Email
jinpeng@mxpharm.com
Country
China
ProdList
75
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8415
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
2964
Advantage
65
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
021-51613915-820 13611835272
Fax
021 51613951
Email
mmwang@sunwaypharm.cn
Country
China
ProdList
9734
Advantage
57
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19915
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
+86-28-85122536 85324413
Fax
+86-28-85326443
Email
market@astatech.cn
Country
China
ProdList
8026
Advantage
55
Wuxi Zhangkun Biochemical Technology Co., Ltd.
Tel
+86 0510-85629785
Fax
+86 0510-85625359
Country
China
ProdList
2327
Advantage
58
Quzhou Juhua Friendship Co., Ltd
Tel
0570-3066667
Fax
0570-3063388
Country
China
ProdList
3930
Advantage
58
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Chemwill Asia Co.,Ltd.
Tel
86-21-51086038
Fax
86-21-51861608
Country
China
ProdList
2930
Advantage
58
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Suzhou yacoo science co.,Ltd
Tel
0512-87182056 18013166090
Fax
0512-87182056
Email
lingling.qi@yacoo.com.cn
Country
China
ProdList
7295
Advantage
60
Shanghai AQBioPharma Co., Ltd.
Tel
13764862135
Fax
51370935-8011
Email
yaoliang.ni@aqbiopharma.com.cn
Country
China
ProdList
2759
Advantage
58
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
16166
Advantage
55
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Suzhou Xinkai Bio-Medical Technology Co., Ltd.
Tel
0512-67213637 13952409868
Email
peter19zhang@163.com
Country
China
ProdList
453
Advantage
55
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9951
Advantage
56
Shanghai Qiao Chemical Science Co., Ltd
Tel
021-58892003
Email
info@qiaochem.com
Country
China
ProdList
5902
Advantage
65
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27313
Advantage
60
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9595
Advantage
55
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20806
Advantage
60
Beijing Hechemist Technology CO.,LTD
Tel
18511709189
Email
sales@hechemist.com
Country
China
ProdList
3433
Advantage
58
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-0371-55629727 13323845623
Fax
037155629727
Email
2885676761@qq.com
Country
China
ProdList
10010
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd.
Tel
027-50664929, 13971561712
Fax
027-50664927 / QQ: 3452835437
Email
hubxys2001@163.com
Country
China
ProdList
1437
Advantage
55
Shanghai Jinsheng Pharmaceutical Co., Ltd.
Tel
1365-13651960330 13651960330
Email
xiangfeixia@jspharmatech.com
Country
China
ProdList
309
Advantage
58
Guangzhou Jhd Chemical Reagent Co., Ltd.
Tel
020-84383047
Fax
020-84380294
Email
sales@jhd.com.cn
Country
China
ProdList
9186
Advantage
65
Shanghai Orgchem Co.,Ltd.
Tel
+86-21-5877 1921
Fax
+86-21-5877 1925
Email
info@chemofchina.com
Country
China
ProdList
9653
Advantage
55
Shandong Ono Chemical Co., Ltd.
Tel
0539-6362799 20）
Fax
0539-6362799（To 20）
Country
China
ProdList
10007
Advantage
58
Chongqing Maohuan Chemical Co.Ltd>
Tel
13996103726
Email
info@bschem.com
Country
China
ProdList
172
Advantage
58
Capot Chemical Co.,Ltd.
Tel
+86-（0）57185586718 +86-13336195806
Fax
+86-571-85864795
Email
sales@capot.com
Country
China
ProdList
29791
Advantage
60
Foshan DaoQi Biological Co., Ltd.
Tel
18062666947
Fax
18062666959
Email
2355880548@qq.com
Country
China
ProdList
4228
Advantage
58
QuZhou Rainfull Chemical Co.,Ltd.
Tel
0570-3062289 13819008176 15068926975
Fax
0570-3063388
Email
527757556@qq.com
Country
China
ProdList
2957
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52693
Advantage
58
Hunan chemfish Scientific co.,ltd
Tel
+8618229978283 18229978283
Email
sales@chemfish.com
Country
China
ProdList
4959
Advantage
58
Henan Alpha Chemical Co., Ltd.
Tel
0371-0371-55055611 18137792234
Fax
QQ：3002694073
Email
3002694073@qq.com
Country
China
ProdList
10526
Advantage
58
More
Less

View Lastest Price from 1,3-Adamantanedicarboxylic acid manufacturers

Shanghai Qyubiotech Co., Ltd.
Product
1,3-Adamantanedicarboxylic acid 39269-10-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
97%+
Supply Ability
10000kgs per Month
Release date
2023-04-19
Career Henan Chemical Co
Product
1,3-Adamantanedicarboxylic acid 39269-10-8
Price
US $1.00/kg
Min. Order
1g
Purity
99%
Supply Ability
100KG
Release date
2018-12-21

39269-10-8, 1,3-Adamantanedicarboxylic acidRelated Search:

1,3-Adamantanediol Adamantane Folic acid Altrenogest Amantadine OXALIC ACID Decane Ethyl 2-(Chlorosulfonyl)acetate Glycine Cyclohexanepropionic acid 1,3-adamantanedimethanol Azelaic acid Cyclooctanecarbaldehyde 2,2-Dimethylglutaric acid 1,3-Dimethyladamantane Dimethyl 1,3-adamantanedicarboxylate 1,3-Cyclohexanedicarboxylic acid CYCLOOCTANEMETHANOL

  • adamantane-1,3-dicarboxylate
  • tricyclo(3.3.1.1(sup3,7))decane-1,3-dicarboxylicacid
  • ADAMANTANE-1,3-DICARBOXYLIC ACID
  • AKOS BC-0656
  • 1,3-ADAMANTANEDICARBOXYLIC ACID
  • 1,3-DICARBOXYADAMANTANE
  • Tricyclo[3.3.1.13,7]decane-1,3-dicarboxylic acid
  • (1s,3s,5r,7r)-AdaMantane-1,3-dicarboxylic acid
  • 1,3-AdaMantanedicarboxylic acid SynonyMs AdaMantane-1,3-dicarboxylic acid
  • 1,3-Adamantanedicarboxylic acid 98%
  • 1,3-Adamantanedicarboxylic Acid &gt
  • 39269-10-8
  • Adamantanes
  • Carboxylic Acids
  • Fused Ring Systems
  • Alicyclic/Etch-Resistant MonomersPolymer Science
  • Carboxylic Acid Monomers
  • Lithography Monomers
  • Monomers
  • Self Assembly&Contact Printing
  • Adamantane derivatives
  • Carboxylic Acids
  • Adamantanes