ChemicalBook > CAS DataBase List > Polydatin

Polydatin

Product Name
Polydatin
CAS No.
27208-80-6
Chemical Name
Polydatin
Synonyms
Resveratrol 3-O-β-D-glucopyranoside;(2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;Pieceid;Plydatin;Piceid>(E)-Piceid;rans-picei;(E)-Polydatin;Polydatin CRS;trans-Polydatin
CBNumber
CB5328918
Molecular Formula
C20H22O8
Formula Weight
390.39
MOL File
27208-80-6.mol
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Polydatin Property

Melting point:
223-226 °C(lit.)
Boiling point:
707.7±60.0 °C(Predicted)
alpha 
-77.5 º (c=0.2, EtOH)
Density 
1.521±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
DMSO, Ethanol, Methanol
pka
9.21±0.10(Predicted)
form 
Solid
color 
Off-White
λmax
305nm(EtOH)(lit.)
InChI
InChI=1/C20H22O8/c21-10-16-17(24)18(25)19(26)20(28-16)27-15-8-12(7-14(23)9-15)2-1-11-3-5-13(22)6-4-11/h1-9,16-26H,10H2/b2-1+/t16-,17-,18+,19-,20-/s3
InChIKey
HSTZMXCBWJGKHG-RPHGGTSJNA-N
SMILES
O(C1C=C(O)C=C(/C=C/C2C=CC(O)=CC=2)C=1)[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O |&1:17,18,19,21,23,r|
LogP
0.412 (est)
CAS DataBase Reference
27208-80-6(CAS DataBase Reference)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
29389090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL89312
Product name
trans-Polydatin
Purity
phyproof? Reference Substance
Packaging
20MG
Price
$309
Updated
2025/07/31
TCI Chemical
Product number
P1878
Product name
Piceid
Purity
>95.0%(HPLC)
Packaging
1g
Price
$25
Updated
2025/07/31
TCI Chemical
Product number
P1878
Product name
Piceid
Purity
>95.0%(HPLC)
Packaging
5g
Price
$81
Updated
2025/07/31
Cayman Chemical
Product number
13932
Product name
Resveratrol-3-O-D-Glycoside (piceide)
Purity
≥98%
Packaging
250mg
Price
$43
Updated
2024/03/01
Cayman Chemical
Product number
13932
Product name
Resveratrol-3-O-D-Glycoside (piceide)
Purity
≥98%
Packaging
500mg
Price
$81
Updated
2024/03/01
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Polydatin Chemical Properties,Usage,Production

Description

Polydatin is a stilbene glucoside and a precursor to trans-resveratrol (Item No. 70675) that has been found in V. vinifera and has diverse biological activities. It scavenges DPPH radicals and inhibits copper-induced lipid peroxidation (IC50s = 198 and 19.1 μM, respectively). Polydatin inhibits the proliferation of, and induces cell cycle arrest at the S phase in, Caco-2 colon cancer cells. It decreases infarct size, cardiomyocyte fibrosis, and apoptosis in a mouse model of myocardial ischemia-reperfusion injury induced by left anterior descending (LAD) coronary artery occlusion when administered at a dose of 40 mg/kg per day.

Chemical Properties

Off-White Solid

Uses

A Stilbenoid glucoside and is a major Resveratrol derivative.

Uses

antioxidant

Definition

ChEBI: A stilbenoid that is trans-resveratrol substituted at position 3 by a beta-D-glucosyl residue.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

References

[1] PIERRE WAFFO TEGUO. Isolation, Identification, and Antioxidant Activity of Three Stilbene Glucosides Newly Extracted from Vitis vinifera Cell Cultures[J]. Journal of Natural Products , 1998, 61 5: 655-657. DOI: 10.1021/np9704819
[2] SALVATORE DE MARIA. Polydatin, a natural precursor of resveratrol, induces cell cycle arrest and differentiation of human colorectal Caco-2 cell.[J]. Journal of Translational Medicine, 2013: 264. DOI: 10.1186/1479-5876-11-264
[3] MING D, SONGYAN L, YAWEN C, et al. trans-Polydatin protects the mouse heart against ischemia/reperfusion injury via inhibition of the renin–angiotensin system (RAS) and Rho kinase (ROCK) activity?[J]. Food & Function, 2017, 6: 2309-2321. DOI: 10.1039/c6fo01842d

Polydatin Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Polydatin manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
Polydatin 27208-80-6
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100 mt
Release date
2024-11-13
Hebei Zhuanglai Chemical Trading Co Ltd
Product
Polydatin 27208-80-6
Price
US $60.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 tons
Release date
2024-11-18
Henan Aochuang Chemical Co.,Ltd.
Product
Polydatin 27208-80-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-10-12

27208-80-6, PolydatinRelated Search:

Phenylhydrazine Neosperidin dihydrochalcone PHENYL VALERATE Resveratrol Oxyresveratrol CHLOROPHOSPHONAZO III Ascorbyl glucoside DanshenP.E Aloe emodin RHAPONTIN 3,5-DIHYDROXY-4'-METHOXYSTILBENE 3-O-BETA-D-GLUCOSIDE PHENYL-BETA-D-GLUCOPYRANOSIDE Polydatin Polydatin Piceid(polydatin) ASTRINGIN ISORHAPHONTIN 2,3,5,4'-TETRAHEDROXYSTILBENE-3-O-D-GLUCOSIDE

  • RESVERATROL GLUCOSIDE
  • RESVERATROL-3-B-D-GLUCOSIDE
  • RESVERATROL 3-BETA-MONO-D-GLUCOSIDE
  • TRANS-RESVERATROL 3-O-BETA-D-GLUCURONIDE
  • TRANS-RESVERATROL-O-BETA-GLUCOSIDE
  • 3-Hydroxy-5-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenyl-beta-D-glucopyranoside
  • 3-HYDROXY-5-(2-(4-HYDROXYPHENYL)ETHENYL)PHENYL-BETA-D-GLUCOSIDE
  • 3, 5, 4'-trihydroxystilbene 3-glucoside
  • 4',5-DIHYDROXYSTILBENE-3-O-BETA-D-GLUCOSIDE
  • 3,4',5-TRIHYDROXYSTILBENE-3-BETA-MONOGLUCOSIDE
  • POLYDATIN(PICEID)(P)
  • TRANS-RESVERATROL-3-O-BETA-D-GLUCOSIDE
  • 3-(β-D-Glucopyranosyloxy)-5-[(E)-2-(4-hydroxyphenyl)vinyl]phenol
  • Resveratrol 3-O-glucoside
  • trans-Resveratrol glucoside
  • 4',5-Dihydroxystilben-3-yl β-D-Glucopyranoside
  • 3-b-mono-D-glucoside
  • Polydatin, 98%, from Polygala japonica Houtt.
  • Resveratrol-3-O-D-Glycoside (piceide)
  • Polydatin 27208-80-6
  • Polygonum cuspidatum glycoside
  • Polydatin, ≥95% (HPLC)
  • 2-(hydroxymethyl)-2-[2-(4-hydroxyphenyl)ethenyl]-6-phenoxyoxane-3,4,4,5-tetrol
  • cis Resveratrol 3-O-β-D-glucopyranoside, 98%
  • trans Resveratrol 3-O-β-D-glucopyranoside, 98%
  • 3-Hydroxy-5-(p-hydroxystyryl)phenyl β-D-Glucoside
  • 3-Hydroxy-5-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenyl β-D-Glucopyranoside
  • E-Resveratrol 3-O-Glucopyranoside
  • Resveratrol 3-Glucoside 4',5-Dihydroxystilben-3-yl beta-D-Glucopyranoside
  • Plydatin
  • Reservatrol-3-β-mono-D-glucoside
  • Resveratrol 3-O-β-D-glucopyranoside
  • (E)-Piceid
  • (E)-Polydatin
  • Pieceid
  • Polydotin peceid
  • trans-Polydatin
  • Polydatin, froM Reynoutria japonica
  • Reynoutria japonica Houtt.
  • trans-Polydatin 〔trans-Piceid〕
  • (3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyra
  • Piceid&gt
  • Polydatin CRS
  • β-D-Glucopyranoside, 3-hydroxy-5-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenyl
  • trans-Resveratrol 3-O-β-D-glucopyranoside
  • rans-picei
  • 4',5-Dihydroxystilben-3-yl beta-D-Glucopyranoside
  • Polydatin USP/EP/BP
  • (2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
  • Polydatin trans-piceid
  • Trans-polydation
  • Piceid, ≥ 95.0%
  • 3,4'-5-Trihydroxystilbene-3-beta-D-glucopyranoside
  • trans-Polydatin-RM
  • Polydatin, 10 mM in DMSO
  • <i>trans</i>-Polydatin
  • trans Resveratrol 3-O-β-D-glucopyranoside, CAS 27208-80-6
  • Abmole M3969-20mg Polydatin 27208-80-6